FR2384262A1 - IMMUNOLOGICAL DETERMINATION PROCESS - Google Patents

IMMUNOLOGICAL DETERMINATION PROCESS

Info

Publication number
FR2384262A1
FR2384262A1 FR7807271A FR7807271A FR2384262A1 FR 2384262 A1 FR2384262 A1 FR 2384262A1 FR 7807271 A FR7807271 A FR 7807271A FR 7807271 A FR7807271 A FR 7807271A FR 2384262 A1 FR2384262 A1 FR 2384262A1
Authority
FR
France
Prior art keywords
active material
determination process
immunologically active
immunological determination
reagent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7807271A
Other languages
French (fr)
Other versions
FR2384262B1 (en
Inventor
Douglas E Hawley
Peter G Tonke
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of FR2384262A1 publication Critical patent/FR2384262A1/en
Application granted granted Critical
Publication of FR2384262B1 publication Critical patent/FR2384262B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • C07D475/06—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4
    • C07D475/08—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4 with a nitrogen atom directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

La présente invention concerne notamment la détermination immunologique. Il s'agit d'un réactif pour la détermination d'une matière immunologiquement active, comprenant la matière immunolo giquement active ou un récepteur qui peut fixer spécifiquement cette matière immunologiquement active, marqués par une substance capable de modifier le degré ou le mode d'activité d'une enzyme. Ce réactif est utile dans une grande variété de dosages immunologiques.The present invention relates in particular to immunological determination. It is a reagent for the determination of an immunologically active material, comprising the immunologically active material or a receptor which can specifically bind this immunologically active material, labeled with a substance capable of modifying the degree or the mode of activity of an enzyme. This reagent is useful in a wide variety of immunoassays.

FR7807271A 1977-03-15 1978-03-14 IMMUNOLOGICAL DETERMINATION PROCESS Granted FR2384262A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB10859/77A GB1595101A (en) 1977-03-15 1977-03-15 Enzyme modifier immunoassay

Publications (2)

Publication Number Publication Date
FR2384262A1 true FR2384262A1 (en) 1978-10-13
FR2384262B1 FR2384262B1 (en) 1983-04-08

Family

ID=9975639

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7807271A Granted FR2384262A1 (en) 1977-03-15 1978-03-14 IMMUNOLOGICAL DETERMINATION PROCESS

Country Status (16)

Country Link
JP (1) JPS53115814A (en)
AT (1) AT367203B (en)
AU (1) AU519326B2 (en)
BE (1) BE864856A (en)
CA (1) CA1102789A (en)
CH (1) CH641570A5 (en)
DE (1) DE2811257A1 (en)
DK (1) DK152313C (en)
ES (2) ES467831A1 (en)
FR (1) FR2384262A1 (en)
GB (1) GB1595101A (en)
IL (1) IL54234A0 (en)
IT (1) IT1158665B (en)
NL (1) NL7802845A (en)
NO (2) NO152955C (en)
SE (1) SE447026B (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0027036A1 (en) * 1979-10-03 1981-04-15 Colin Henry Self Assay method using enzymes as labeling substances
EP0034775A2 (en) * 1980-02-22 1981-09-02 Hans A. Dr. Thoma Homogeneous process for the competitive determination of ligands
EP0063064A1 (en) * 1981-03-24 1982-10-20 Laboratoire Des Stallergenes Reagent for the radio-or enzymo-immunological determination of IgE
EP0117648A2 (en) * 1983-01-31 1984-09-05 Boots-Celltech Diagnostics Limited Immunoassay
EP0590109A1 (en) * 1992-03-04 1994-04-06 Akzo Nobel N.V. $i(IN VIVO) BINDING PAIR PRETARGETING
US5965106A (en) * 1992-03-04 1999-10-12 Perimmune Holdings, Inc. In vivo binding pair pretargeting

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4273866A (en) * 1979-02-05 1981-06-16 Abbott Laboratories Ligand analog-irreversible enzyme inhibitor conjugates and methods for use
US4341865A (en) 1980-07-21 1982-07-27 Abbott Laboratories Determination of thyroxine binding globulin
GB2116979B (en) * 1982-02-25 1985-05-15 Ward Page Faulk Conjugates of proteins with anti-tumour agents
AU574646B2 (en) * 1982-07-19 1988-07-14 Cooperbiomedical Inc. Enzyme assay method
US4650751A (en) * 1983-04-29 1987-03-17 Technicon Instruments Corporation Protected binding assay avoiding non-specific protein interference
JPS607362A (en) * 1983-06-27 1985-01-16 Fujirebio Inc Measurement of antigen determinant-containing substance using enzyme
US4837395A (en) * 1985-05-10 1989-06-06 Syntex (U.S.A.) Inc. Single step heterogeneous assay
CA1330378C (en) * 1986-05-08 1994-06-21 Daniel J. Coughlin Amine derivatives of folic acid analogs
US4939264A (en) * 1986-07-14 1990-07-03 Abbott Laboratories Immunoassay for opiate alkaloids and their metabolites; tracers, immunogens and antibodies
IL85596A (en) * 1987-05-18 1992-06-21 Technicon Instr Method for a specific binding enzyme immunoassay
US5972630A (en) * 1991-08-19 1999-10-26 Dade Behring Marburg Gmbh Homogeneous immunoassays using enzyme inhibitors
WO1999060401A1 (en) * 1998-05-15 1999-11-25 Sekisui Chemical Co., Ltd. Immunoassay reagents and immunoassay method
US6811998B2 (en) 1999-06-25 2004-11-02 Roche Diagnostics Operations, Inc. Conjugates of uncompetitive inhibitors of inosine monophosphate dehydrogenase
US8394813B2 (en) * 2000-11-14 2013-03-12 Shire Llc Active agent delivery systems and methods for protecting and administering active agents
US8664181B2 (en) * 2007-02-16 2014-03-04 Ktb Tumorforschungsgesellschaft Mbh Dual acting prodrugs

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2308005A1 (en) * 1975-04-15 1976-11-12 Hadaway Robert Drive in wall plug fastener - has body provided with indentations and covered with pliable externally smooth coating

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0027036A1 (en) * 1979-10-03 1981-04-15 Colin Henry Self Assay method using enzymes as labeling substances
WO1981001057A1 (en) * 1979-10-03 1981-04-16 C Self Assay method using enzymes as labelling substances
EP0034775A2 (en) * 1980-02-22 1981-09-02 Hans A. Dr. Thoma Homogeneous process for the competitive determination of ligands
EP0034775A3 (en) * 1980-02-22 1981-09-09 Hans A. Dr. Thoma Homogeneous process for the competitive determination of ligands
EP0063064A1 (en) * 1981-03-24 1982-10-20 Laboratoire Des Stallergenes Reagent for the radio-or enzymo-immunological determination of IgE
EP0117648A2 (en) * 1983-01-31 1984-09-05 Boots-Celltech Diagnostics Limited Immunoassay
EP0117648A3 (en) * 1983-01-31 1988-02-03 Boots-Celltech Diagnostics Limited Immunoassay
EP0590109A1 (en) * 1992-03-04 1994-04-06 Akzo Nobel N.V. $i(IN VIVO) BINDING PAIR PRETARGETING
EP0590109A4 (en) * 1992-03-04 1995-04-19 Akzo Nv -i(IN VIVO) BINDING PAIR PRETARGETING.
US5578289A (en) * 1992-03-04 1996-11-26 Akzo N.V. In vivo binding pair pretargeting
US5807534A (en) * 1992-03-04 1998-09-15 Akzo Nobel N.V. In vivo binding pair pretargeting
US5965106A (en) * 1992-03-04 1999-10-12 Perimmune Holdings, Inc. In vivo binding pair pretargeting

Also Published As

Publication number Publication date
ES475984A1 (en) 1979-06-16
NO780902L (en) 1978-09-18
AU3396578A (en) 1979-09-13
BE864856A (en) 1978-09-14
IL54234A0 (en) 1978-06-15
NO844764L (en) 1978-09-18
DK152313C (en) 1988-09-26
DK152313B (en) 1988-02-15
ATA182178A (en) 1981-10-15
NO152955B (en) 1985-09-09
DE2811257A1 (en) 1978-09-21
NO152955C (en) 1985-12-18
NO154814B (en) 1986-09-15
CA1102789A (en) 1981-06-09
NO154814C (en) 1986-12-29
SE7802923L (en) 1978-09-16
JPS53115814A (en) 1978-10-09
NL7802845A (en) 1978-09-19
IT1158665B (en) 1987-02-25
FR2384262B1 (en) 1983-04-08
CH641570A5 (en) 1984-02-29
AT367203B (en) 1982-06-11
SE447026B (en) 1986-10-20
DK114778A (en) 1978-09-16
ES467831A1 (en) 1979-09-01
GB1595101A (en) 1981-08-05
IT7821256A0 (en) 1978-03-15
AU519326B2 (en) 1981-11-26

Similar Documents

Publication Publication Date Title
FR2384262A1 (en) IMMUNOLOGICAL DETERMINATION PROCESS
US4470925A (en) Immunoglobulin half-molecules and process for producing hybrid antibodies
IT8249401A0 (en) METHOD FOR DETERMINING THE PRESENCE OF ANALYTE IN SOLUTION, PARTICULARLY FOR IMMUNOLOGICAL ASSAYS
AU3777989A (en) Heterofunctional cellular immunological reagents, vaccines containing same and methods for the use of same
DE59108149D1 (en) UNIVERSAL BINDING FILM
FR2366568A1 (en) METHOD FOR DETERMINING AN IMMUNOLOGICALLY ACTIVE SUBSTANCE
FR2412870A1 (en) HOT-DEVELOPABLE PHOTOSENSITIVE MATERIALS
NO822853L (en) Antigen Assay.
EP0151320A3 (en) Pure alkaline phosphatase, its preparation and use
ATE112630T1 (en) REAGENT INCLUDING ENZYME DONOR.
IT7920592A0 (en) DETERMINATION OF ANTIGENS OR ANTIBODIES.
DE3485289D1 (en) MONOCLONAL ANTIBODY VERSION FOR DIAGNOSTIC USE.
IT1207589B (en) COMPOSITION OF CROSS-PROTECTIVE HUMAN MONOCLONAL ANTIBODIES.
ES511156A0 (en) A METHOD OF DETERMINING THE PRESENCE OF AN ANTIGEN IN A LIQUID MEDIUM SUSPECTED TO CONTAIN IT.
KR850002385A (en) Method and reagent for measuring PIVKA-II
Talal et al. Immunochemical evidence for multiple molecular forms of crystalline glutamic dehydrogenase
FR2373795A1 (en) IMMUNOLOGICAL DOSAGE BY FIXED ENZYME
NL7705996A (en) PROCESS FOR PREPARATION OF MADE INSOLUBLE ENZYME.
EP0096463A1 (en) Immunoglobulin half-molecules and process for producing hybrid antibodies
ES8504257A1 (en) Determination of streptococci.
ES2094784T3 (en) PROCEDURE FOR THE DETERMINATION OF AN ANALYTE.
FR2418464A1 (en) IMMUNOCHEMICAL DOSAGE
FR2383919A1 (en) DETERMINATION OF B-ENDORPHINE
GB1540728A (en) Polyiodothyronine immunoassay
ES8401261A1 (en) Procedure for immunological determinations using two antibodies, the second antibody being purified by affinity chromatography, and supports therefor.

Legal Events

Date Code Title Description
ST Notification of lapse