FR2378796A1 - Derives de l'ethoxyquine 6-ethoxy-1,2-dihydro-2,2,4-trimethylquinoleine, leur preparation et compositions en contenant - Google Patents

Derives de l'ethoxyquine 6-ethoxy-1,2-dihydro-2,2,4-trimethylquinoleine, leur preparation et compositions en contenant

Info

Publication number
FR2378796A1
FR2378796A1 FR7802294A FR7802294A FR2378796A1 FR 2378796 A1 FR2378796 A1 FR 2378796A1 FR 7802294 A FR7802294 A FR 7802294A FR 7802294 A FR7802294 A FR 7802294A FR 2378796 A1 FR2378796 A1 FR 2378796A1
Authority
FR
France
Prior art keywords
preparation
derivatives
dihydro
ethoxy
compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7802294A
Other languages
English (en)
Other versions
FR2378796B1 (fr
Inventor
Emil Menachemoff
Oded Awerbuch
Raphael R G Haber
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abic Ltd
Original Assignee
Abic Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abic Ltd filed Critical Abic Ltd
Publication of FR2378796A1 publication Critical patent/FR2378796A1/fr
Application granted granted Critical
Publication of FR2378796B1 publication Critical patent/FR2378796B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/12—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by acids having the group -X-C(=X)-X-, or halides thereof, in which each X means nitrogen, oxygen, sulfur, selenium or tellurium, e.g. carbonic acid, carbamic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/048—Pyridine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Fodder In General (AREA)
  • Quinoline Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Anti-Oxidant Or Stabilizer Compositions (AREA)

Abstract

L'invention concerne des dérivés de la 6-éthoxy-1,2-dihydro-2,2,4-triméthylquinoléine. Elle vise également la préparation de ces composés. Les dérivés susmentionnés possèdent, par rapport à l'éthoxyquine, de nombreux avantages étant donné que l'on peut les obtenir sous une forme pure convenant à la préparation de compositions pharmaceutiques et qu'ils ne présentent ni odeur, ni saveur.
FR7802294A 1977-01-27 1978-01-27 Derives de l'ethoxyquine 6-ethoxy-1,2-dihydro-2,2,4-trimethylquinoleine, leur preparation et compositions en contenant Granted FR2378796A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL51342A IL51342A (en) 1977-01-27 1977-01-27 Ethoxyquin derivatives,their preparation and pharmaceutical and veterinary compositions comprising them

Publications (2)

Publication Number Publication Date
FR2378796A1 true FR2378796A1 (fr) 1978-08-25
FR2378796B1 FR2378796B1 (fr) 1983-07-29

Family

ID=11049365

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7802294A Granted FR2378796A1 (fr) 1977-01-27 1978-01-27 Derives de l'ethoxyquine 6-ethoxy-1,2-dihydro-2,2,4-trimethylquinoleine, leur preparation et compositions en contenant

Country Status (15)

Country Link
US (2) US4305932A (fr)
JP (1) JPS5395979A (fr)
AU (1) AU523183B2 (fr)
BE (1) BE863293A (fr)
DE (1) DE2802630A1 (fr)
DK (1) DK39778A (fr)
ES (1) ES466940A1 (fr)
FR (1) FR2378796A1 (fr)
GB (1) GB1577391A (fr)
IE (1) IE46499B1 (fr)
IL (1) IL51342A (fr)
IT (1) IT7819738A0 (fr)
NL (1) NL7801022A (fr)
NZ (1) NZ186212A (fr)
ZA (1) ZA78292B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6316012B1 (en) 1992-09-01 2001-11-13 L'oreal Cosmetic or pharmaceutical composition comprising, in combination, a peroxidase and an anti-singlet oxygen agent

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL51342A (en) 1977-01-27 1980-11-30 Abic Ltd Ethoxyquin derivatives,their preparation and pharmaceutical and veterinary compositions comprising them
EP0028765B1 (fr) * 1979-11-09 1983-05-04 Bayer Ag Dérivés de l'alkylurée pour le traitement des maladies du métabolisme des graisses; procédé pour leur préparation, leur application dans des médicaments pour le traitement des altérations du métabolisme des graisses, médicaments les contenant, procédé pour leur préparation, ainsi que quelques dérivés de l'alkylurée
DE2945238A1 (de) * 1979-11-09 1981-05-21 Bayer Ag, 5090 Leverkusen Verwendung von alkylharnstoffderivaten in arzneimitteln zur behandlung von fettstoffwechselstoerungen
US5891491A (en) * 1997-07-25 1999-04-06 Solutia Inc. Use of dihydroxyquinoline compounds to extend the shelf life of products of mammals and fish
EP1051165A2 (fr) 1998-01-26 2000-11-15 Mitokor Agents protegeant les mitochondries et utilises dans le traitement des maladies associees aux mitochondries
US6017564A (en) * 1998-04-14 2000-01-25 Solutia Inc. Treatment of stressed animals with dihydroxyquinoline compounds
FR2784988B1 (fr) * 1998-10-23 2002-09-20 Adir Nouveaux composes dihydro et tetrahydroquinoleiniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US7335669B2 (en) * 2002-02-27 2008-02-26 Novus International, Inc. Use of dihydroquinoline to aid in increasing milk production and feed utilization
CN1296358C (zh) * 2003-07-18 2007-01-24 宜兴市天石饲料有限公司 一种合成乙氧基喹啉的方法
US7910604B2 (en) * 2006-07-12 2011-03-22 Novus International, Inc. Antioxidant combinations for use in feed rations to increase milk production and milk fat
US8691843B2 (en) * 2006-07-12 2014-04-08 Novus International, Inc. Antioxidant combinations for use in ruminant feed rations
US8404714B2 (en) * 2008-01-04 2013-03-26 Novus International, Inc. Combinations to improve animal health and performance
UA117095C2 (uk) 2011-12-22 2018-06-25 Аліос Біофарма, Інк. Нуклеозидна сполука або її фармацевтично прийнятна сіль
USRE48171E1 (en) 2012-03-21 2020-08-25 Janssen Biopharma, Inc. Substituted nucleosides, nucleotides and analogs thereof
US9441007B2 (en) 2012-03-21 2016-09-13 Alios Biopharma, Inc. Substituted nucleosides, nucleotides and analogs thereof
RU2677883C1 (ru) * 2017-10-13 2019-01-22 федеральное государственное бюджетное образовательное учреждение высшего образования "Воронежский государственный университет" (ФГБОУ ВО "ВГУ") Применение 6-гидрокси-2,2,4-триметил-1,2-дигидрохинолина в качестве гепатопротектора

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB909599A (en) * 1960-04-06 1962-10-31 Monsanto Chemicals Mycobacteriostatic compositions
GB945530A (en) * 1961-11-08 1964-01-02 Church & Company Fittings Ltd Improvements in supporting structures for display, storage and like purposes
FR1404848A (fr) * 1963-08-07 1965-07-02 Monsanto Co Procédé de préparation d'antioxydants utiles dans les aliments pour animaux et nouvelles compositions alimentaires ainsi obtenues
FR1542278A (fr) * 1966-11-05 1968-10-11 Bayer Ag Composés hétérocycliques

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2426012A (en) * 1945-11-14 1947-08-19 Pyridium Corp Glucosidamino compounds of alkoxy pyridine
US2637727A (en) * 1951-09-12 1953-05-05 Us Agriculture Nu-(3, 4, 6-triacetyl-d-glucosyl) piperidine and method of preparing same
FR3153M (fr) * 1963-03-01 1965-03-01 Houde Lab Médicament pour le traitement des affections des coronaires, a base d'isopropylidene-2',3' adénosine.
DE1905606A1 (de) * 1969-02-05 1970-08-20 Basf Ag 1-Acyl-hydro-chinoline
GB1260234A (en) 1969-06-12 1972-01-12 Beecham Group Ltd Veterinary methods and compositions
US3705147A (en) * 1969-08-22 1972-12-05 Univ Utah 3-deazapyrimidine nucleosides and method of preparation thereof
US4006178A (en) * 1971-09-24 1977-02-01 Ciba-Geigy Corporation Process for the manufacture of dicyanovinyl compounds
IL51342A (en) 1977-01-27 1980-11-30 Abic Ltd Ethoxyquin derivatives,their preparation and pharmaceutical and veterinary compositions comprising them

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB909599A (en) * 1960-04-06 1962-10-31 Monsanto Chemicals Mycobacteriostatic compositions
GB945530A (en) * 1961-11-08 1964-01-02 Church & Company Fittings Ltd Improvements in supporting structures for display, storage and like purposes
FR1404848A (fr) * 1963-08-07 1965-07-02 Monsanto Co Procédé de préparation d'antioxydants utiles dans les aliments pour animaux et nouvelles compositions alimentaires ainsi obtenues
FR1542278A (fr) * 1966-11-05 1968-10-11 Bayer Ag Composés hétérocycliques

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CA1977 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6316012B1 (en) 1992-09-01 2001-11-13 L'oreal Cosmetic or pharmaceutical composition comprising, in combination, a peroxidase and an anti-singlet oxygen agent

Also Published As

Publication number Publication date
ZA78292B (en) 1979-02-28
AU523183B2 (en) 1982-07-15
IL51342A0 (en) 1977-03-31
IT7819738A0 (it) 1978-01-27
DK39778A (da) 1978-07-28
NL7801022A (nl) 1978-07-31
IL51342A (en) 1980-11-30
ES466940A1 (es) 1978-10-01
US4305932A (en) 1981-12-15
IE46499B1 (en) 1983-06-29
IE780180L (en) 1978-07-27
FR2378796B1 (fr) 1983-07-29
GB1577391A (en) 1980-10-22
DE2802630A1 (de) 1978-08-03
NZ186212A (en) 1980-10-24
JPS5395979A (en) 1978-08-22
AU3263178A (en) 1979-08-02
US4402945A (en) 1983-09-06
BE863293A (fr) 1978-07-25

Similar Documents

Publication Publication Date Title
FR2378796A1 (fr) Derives de l'ethoxyquine 6-ethoxy-1,2-dihydro-2,2,4-trimethylquinoleine, leur preparation et compositions en contenant
FR2714378B1 (fr) Dérivés de l'indol-2-one substitués en 3 par un groupe azoté, leur préparation, les compositions pharmaceutiques en contenant.
ATE153855T1 (de) Zusammensetzungen zur behandlung von glaukoma die prostaglandine und clonidinderivate enthalten
DE69706566D1 (de) Verwendung von dem chelatbildner clioquinol zur herstellung eines arzneimittelszur behandlung von alzheimerschen krankheit
AR022008A1 (es) Una composicion de liberacion controlada de galantamina, un proceso para la preparacion de la misma, y el uso de dicha composicion para la preparacion de un medicamento
DE59009351D1 (de) Neue arylpyridazine, ihre herstellung, verwendung und sie enthaltende arzneimittel.
GR890100467A (el) Μεθοδος δια την παρασκευη ενδοφλεβιου φαρμακευτικης συνθεσεως.
MX9102582A (es) Derivados de indol 3,7-disubstituidos, procedimiento para su preparacion y composicion farmaceutica que los contiene.
ATE210147T1 (de) Glycokonjugate von modifizierten camptothecin- derivaten(a- oder b-ring-verknüpfung)
YU30092A (sr) Bis-naftalimidi koji sadrže amino kiseline izvedene linkere kao antokancerogenska sredstva
ES2108129T3 (es) Nuevos derivados de pirazina, su preparacion y empleo.
CO4770947A1 (es) Composiciones antimicrobianas que contienen alcohol c3-c6
TR200002078T2 (tr) Sentetik polisakkaridler, hazırlanmaları için proses ve bunları içeren farmasötik kompozisyonlar.
EP0281070A3 (fr) Composé pharmaceutique pour le traitement du cancer
OA09352A (fr) "Méthode de préparation de dérivés de furo (3,4-c) pyridine sous forme non-racémique".
IL74138A (en) 4,6,6a,7,8,12b-hexahydro-indolo(4,3-ab)phenanthridines,their production and pharmaceutical compositions containing them
KR970032819A (ko) 미백화장료 조성물
FR2687154B1 (fr) Nouveau derive de l'isoindolinone, sa preparation et les compositions pharmaceutiques qui le contiennent.
AU6724581A (en) Plenylpiperazine derivatives of 1,3,4-oxiadiazolylphends
ATE159511T1 (de) Derivate von n,n,n',n'-tetrasubstituierten 1,2- ethylendiamin-verbindungen
KR910002792A (ko) 1-치환된-2-(3-아미노-1-프로피닐)피롤리딘 유도체, 그에 의한 중추 콜린성 기능 장해 치료 방법 및 그로구성되는 제약학적 조성물
HUT54969A (en) Process for producing substituted biphenyl derivatives and pharmaceutical compositions containing them
AU1621888A (en) Pharmaceutical compositions for the treatment of cerebral psycho-organic syndromes
JPS51139620A (en) A preventive method against pine weevils
KR920700641A (ko) 클로르메티아졸의 신경 변성 예방 및(또는) 치료용 용도

Legal Events

Date Code Title Description
ST Notification of lapse