FR2378521A1 - Derives du carbostyrile, utiles notamment comme stimulants des centres b- adrenorecepteurs, et leur procede de preparation - Google Patents

Derives du carbostyrile, utiles notamment comme stimulants des centres b- adrenorecepteurs, et leur procede de preparation

Info

Publication number
FR2378521A1
FR2378521A1 FR7638918A FR7638918A FR2378521A1 FR 2378521 A1 FR2378521 A1 FR 2378521A1 FR 7638918 A FR7638918 A FR 7638918A FR 7638918 A FR7638918 A FR 7638918A FR 2378521 A1 FR2378521 A1 FR 2378521A1
Authority
FR
France
Prior art keywords
adrenoreceptor
stimulants
centers
useful
preparation process
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7638918A
Other languages
English (en)
French (fr)
Other versions
FR2378521B1 (en, 2012
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Co Ltd
Original Assignee
Otsuka Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharmaceutical Co Ltd filed Critical Otsuka Pharmaceutical Co Ltd
Publication of FR2378521A1 publication Critical patent/FR2378521A1/fr
Application granted granted Critical
Publication of FR2378521B1 publication Critical patent/FR2378521B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/24—Oxygen atoms attached in position 8
    • C07D215/26—Alcohols; Ethers thereof
    • C07D215/32—Esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/24—Oxygen atoms attached in position 8
    • C07D215/26—Alcohols; Ethers thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FR7638918A 1976-10-08 1976-12-23 Derives du carbostyrile, utiles notamment comme stimulants des centres b- adrenorecepteurs, et leur procede de preparation Granted FR2378521A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP51121423A JPS609713B2 (ja) 1976-10-08 1976-10-08 カルボスチリル誘導体

Publications (2)

Publication Number Publication Date
FR2378521A1 true FR2378521A1 (fr) 1978-08-25
FR2378521B1 FR2378521B1 (en, 2012) 1979-06-29

Family

ID=14810767

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7638918A Granted FR2378521A1 (fr) 1976-10-08 1976-12-23 Derives du carbostyrile, utiles notamment comme stimulants des centres b- adrenorecepteurs, et leur procede de preparation

Country Status (10)

Country Link
US (1) US4223137A (en, 2012)
JP (1) JPS609713B2 (en, 2012)
BE (1) BE849794A (en, 2012)
CA (1) CA1074801A (en, 2012)
CH (1) CH618431A5 (en, 2012)
DE (1) DE2658544C2 (en, 2012)
FR (1) FR2378521A1 (en, 2012)
GB (1) GB1540628A (en, 2012)
NL (1) NL174041C (en, 2012)
SE (1) SE434395B (en, 2012)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH17194A (en) * 1980-03-06 1984-06-19 Otsuka Pharma Co Ltd Novel carbostyril derivatives,and pharmaceutical composition containing the same
US4322425A (en) * 1980-03-14 1982-03-30 Otsuka Pharmaceutical Co., Ltd. Compositions for treating glaucoma
FI77852C (fi) * 1981-02-17 1989-05-10 Otsuka Pharma Co Ltd Foerfarande foer framstaellning av nya, saosom hjaertmediciner anvaendbara substituerade amid- och (maettad heterocykel)karbonylkarbostyrilderivat.
US4456757A (en) * 1981-03-20 1984-06-26 Asahi Kasei Kogyo Kabushiki Kaisha Isoquinolinesulfonyl derivatives and process for the preparation thereof
ATE27451T1 (de) * 1981-03-24 1987-06-15 Ciba Geigy Ag Acyl-chinolinonderivate, verfahren zu ihrer herstellung, diese enthaltende pharmazeutische praeparate und ihre verwendung.
GB8334494D0 (en) * 1983-12-24 1984-02-01 Tanabe Seiyaku Co Carbostyril derivatives
JPS60173736U (ja) * 1984-04-25 1985-11-18 株式会社昭和製作所 緩衝器用サブタンク
JPS61191767A (ja) * 1985-02-20 1986-08-26 辻本　夘太郎 植物張り家屋
JPS62113672A (ja) * 1985-11-12 1987-05-25 本田技研工業株式会社 リヤクツシヨン用リザ−ブタンク
JPS6348401U (en, 2012) * 1986-09-17 1988-04-01
JPS63106132A (ja) * 1986-10-24 1988-05-11 Mazda Motor Corp 車両のサスペンシヨン装置
US4687776A (en) * 1986-10-24 1987-08-18 Warner-Lambert Company Drug stabilization
JPS6374545U (en, 2012) * 1986-10-31 1988-05-18
JPS6417047U (en, 2012) * 1987-07-21 1989-01-27
US4894219A (en) * 1988-03-29 1990-01-16 University Of Florida Beta-agonist carbostyril derivatives, assay method and pharmacological composition
JPH026831U (en, 2012) * 1988-06-28 1990-01-17
US6653323B2 (en) 2001-11-13 2003-11-25 Theravance, Inc. Aryl aniline β2 adrenergic receptor agonists
TWI249515B (en) 2001-11-13 2006-02-21 Theravance Inc Aryl aniline beta2 adrenergic receptor agonists
US20030229058A1 (en) 2001-11-13 2003-12-11 Moran Edmund J. Aryl aniline beta2 adrenergic receptor agonists
JP2005527618A (ja) 2002-05-28 2005-09-15 セラヴァンス インコーポレーテッド アルコキシアリールβ２アドレナリン作動性レセプターアゴニスト
MXPA05005661A (es) * 2002-11-27 2005-11-23 Artesian Therapeutics Inc Compuestos con actividad antagonista o antagonista parcial mixta inhibidora de fosfodiesterasa y beta-adrenergica para el tratamiento de insuficiencia cardiaca.
TW200526547A (en) 2003-09-22 2005-08-16 Theravance Inc Amino-substituted ethylamino β2 adrenergic receptor agonists
TW200531692A (en) 2004-01-12 2005-10-01 Theravance Inc Aryl aniline derivatives as β2 adrenergic receptor agonists
FR2869893B1 (fr) * 2004-05-06 2006-07-28 Rhodia Chimie Sa Nouveaux granules de phosphates de calcium de type hydroxyapatite, leur procede de preparation et leurs applications
US7307076B2 (en) 2004-05-13 2007-12-11 Boehringer Ingelheim International Gmbh Beta agonists for the treatment of respiratory diseases
WO2005110990A1 (de) * 2004-05-13 2005-11-24 Boehringer Ingelheim International Gmbh Hydroxy-substituierte benzkondensierte heterozyklen als betaagonisten zur behandlung von atemwegserkrankungen
CN1984876A (zh) 2004-06-03 2007-06-20 施万制药 二胺类β2肾上腺素能受体激动剂
JP2008512470A (ja) 2004-09-10 2008-04-24 セラヴァンス， インコーポレーテッド アミジン置換アリールアニリン化合物
GB0624757D0 (en) * 2006-12-12 2007-01-17 Sosei R & D Ltd Novel compounds
US9090618B2 (en) 2012-12-27 2015-07-28 Purdue Pharma L.P. Substituted benzimidazole-type piperidine compounds and uses thereof
WO2014108449A1 (en) 2013-01-08 2014-07-17 Atrogi Ab A screening method, a kit, a method of treatment and a compound for use in a method of treatment
GB201714736D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714740D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714734D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714745D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201903832D0 (en) 2019-03-20 2019-05-01 Atrogi Ab New compounds and methods
GB202205895D0 (en) 2022-04-22 2022-06-08 Atrogi Ab New medical uses
WO2024153813A1 (en) 2023-01-20 2024-07-25 Atrogi Ab Beta 2-adrenergic receptor agonists for treatment or prevention of muscle wasting
GB202302225D0 (en) 2023-02-16 2023-04-05 Atrogi Ab New medical uses
GB202303229D0 (en) 2023-03-06 2023-04-19 Atrogi Ab New medical uses

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2461595A1 (de) * 1974-01-31 1976-05-13 Otsuka Pharma Co Ltd Carbostyril- und 3,4-dihydrocarbostyril-derivate, verfahren zu ihrer herstellung und arzneimittel

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3975391A (en) * 1973-12-26 1976-08-17 Otsuka Pharmaceutical Company Limited 5-[1-Hydroxy-2-(substituted-amino)]ethyl-8-hydroxy-3,4-dihydrocarbostyril derivatives
JPS539227B2 (en, 2012) * 1973-12-26 1978-04-04
US4026897A (en) * 1974-01-31 1977-05-31 Otsuka Pharmaceutical Company 5-[1-Hydroxy-2-(substituted-amino)]alkyl-8-hydroxycarbostyril derivatives
US3994901A (en) * 1974-06-13 1976-11-30 Otsuka Pharmaceutical Company Limited 5-[1-Hydroxy-2-(substituted-amino)]alkyl-8-hydroxy-3,4-dihydrocarbostyril derivatives
FI58329C (fi) * 1974-11-08 1981-01-12 Otsuka Pharma Co Ltd Foerfarande foer framstaellning av i 8-staellning substituerade 5-(3'-alkylamino-2'-hydroxi)propoxi-3,4-dihydrokarbostyrilderivat

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2461595A1 (de) * 1974-01-31 1976-05-13 Otsuka Pharma Co Ltd Carbostyril- und 3,4-dihydrocarbostyril-derivate, verfahren zu ihrer herstellung und arzneimittel

Also Published As

Publication number Publication date
JPS609713B2 (ja) 1985-03-12
AU2085576A (en) 1978-04-06
NL174041C (nl) 1984-04-16
FR2378521B1 (en, 2012) 1979-06-29
CA1074801A (en) 1980-04-01
NL7614329A (nl) 1978-04-11
DE2658544C2 (de) 1985-10-03
SE434395B (sv) 1984-07-23
CH618431A5 (en, 2012) 1980-07-31
BE849794A (fr) 1977-04-15
JPS5346983A (en) 1978-04-27
GB1540628A (en) 1979-02-14
DE2658544A1 (de) 1978-04-13
NL174041B (nl) 1983-11-16
US4223137A (en) 1980-09-16
SE7614539L (sv) 1978-04-09

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