FR2373558A1 - Nouveaux esters de spiramycine, leur preparation et la composition pharmaceutique les contenant - Google Patents
Nouveaux esters de spiramycine, leur preparation et la composition pharmaceutique les contenantInfo
- Publication number
- FR2373558A1 FR2373558A1 FR7736836A FR7736836A FR2373558A1 FR 2373558 A1 FR2373558 A1 FR 2373558A1 FR 7736836 A FR7736836 A FR 7736836A FR 7736836 A FR7736836 A FR 7736836A FR 2373558 A1 FR2373558 A1 FR 2373558A1
- Authority
- FR
- France
- Prior art keywords
- spiramycin
- esters
- preparation
- new
- pharmaceutical composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- ACTOXUHEUCPTEW-BWHGAVFKSA-N 2-[(4r,5s,6s,7r,9r,10r,11e,13e,16r)-6-[(2s,3r,4r,5s,6r)-5-[(2s,4r,5s,6s)-4,5-dihydroxy-4,6-dimethyloxan-2-yl]oxy-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-10-[(2s,5s,6r)-5-(dimethylamino)-6-methyloxan-2-yl]oxy-4-hydroxy-5-methoxy-9,16-dimethyl-2-o Chemical class O([C@H]1/C=C/C=C/C[C@@H](C)OC(=O)C[C@@H](O)[C@@H]([C@H]([C@@H](CC=O)C[C@H]1C)O[C@H]1[C@@H]([C@H]([C@H](O[C@@H]2O[C@@H](C)[C@H](O)[C@](C)(O)C2)[C@@H](C)O1)N(C)C)O)OC)[C@@H]1CC[C@H](N(C)C)[C@@H](C)O1 ACTOXUHEUCPTEW-BWHGAVFKSA-N 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 241001465754 Metazoa Species 0.000 abstract 1
- 239000004187 Spiramycin Substances 0.000 abstract 1
- 241000191967 Staphylococcus aureus Species 0.000 abstract 1
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000005569 butenylene group Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 125000001501 propionyl group Chemical group O=C([*])C([H])([H])C([H])([H])[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229960001294 spiramycin Drugs 0.000 abstract 1
- 229930191512 spiramycin Natural products 0.000 abstract 1
- 235000019372 spiramycin Nutrition 0.000 abstract 1
- 230000004936 stimulating effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB51257/76A GB1540397A (en) | 1976-12-08 | 1976-12-08 | Spiramycin esters |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2373558A1 true FR2373558A1 (fr) | 1978-07-07 |
| FR2373558B1 FR2373558B1 (en, 2012) | 1980-04-25 |
Family
ID=10459281
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7736836A Granted FR2373558A1 (fr) | 1976-12-08 | 1977-12-07 | Nouveaux esters de spiramycine, leur preparation et la composition pharmaceutique les contenant |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US4174391A (en, 2012) |
| JP (1) | JPS5371092A (en, 2012) |
| BE (1) | BE861603A (en, 2012) |
| DE (1) | DE2754323A1 (en, 2012) |
| FR (1) | FR2373558A1 (en, 2012) |
| GB (1) | GB1540397A (en, 2012) |
| NL (1) | NL7713320A (en, 2012) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE468119T1 (de) | 2006-06-12 | 2010-06-15 | Univ Ramot | Verfahren zur behandlung von krebs |
| CN105456283B (zh) * | 2015-12-30 | 2018-08-28 | 中山大学 | 大环内酯类抗生素或其药用盐在制备抗手足口病药物中的应用 |
| KR102375444B1 (ko) * | 2017-07-04 | 2022-03-17 | 쉔양 푸양 파마슈티컬 테크놀로지 컴퍼니 리미티드 | 종양을 치료 및/또는 예방하는 약물 제조에서 이소발레릴 스피라마이신i, ii 및/또는 iii의 응용 및 약물 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR5537M (en, 2012) * | 1966-01-06 | 1967-11-13 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB785191A (en) * | 1955-04-13 | 1957-10-23 | Rhone Poulenc Sa | Hydrogenated spiramycins |
| GB796311A (en) * | 1955-12-01 | 1958-06-11 | Rhone Poulenc Sa | Improvements in or relating to esters of spiramycins |
| US3000786A (en) * | 1957-06-14 | 1961-09-19 | Ciba Pharm Prod Inc | Process for making tetrahydro-spiramycin a |
| FR2100880B1 (en, 2012) * | 1970-07-09 | 1975-03-14 | Kyowa Hakko Kogyo Kk |
-
1976
- 1976-12-08 GB GB51257/76A patent/GB1540397A/en not_active Expired
-
1977
- 1977-12-01 NL NL7713320A patent/NL7713320A/xx not_active Application Discontinuation
- 1977-12-06 DE DE19772754323 patent/DE2754323A1/de active Granted
- 1977-12-06 US US05/857,999 patent/US4174391A/en not_active Expired - Lifetime
- 1977-12-06 JP JP14579277A patent/JPS5371092A/ja active Granted
- 1977-12-07 FR FR7736836A patent/FR2373558A1/fr active Granted
- 1977-12-07 BE BE183253A patent/BE861603A/xx not_active IP Right Cessation
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR5537M (en, 2012) * | 1966-01-06 | 1967-11-13 |
Also Published As
| Publication number | Publication date |
|---|---|
| NL7713320A (nl) | 1978-06-12 |
| US4174391A (en) | 1979-11-13 |
| JPS6131114B2 (en, 2012) | 1986-07-17 |
| DE2754323A1 (de) | 1978-06-15 |
| BE861603A (fr) | 1978-06-07 |
| FR2373558B1 (en, 2012) | 1980-04-25 |
| JPS5371092A (en) | 1978-06-24 |
| DE2754323C2 (en, 2012) | 1988-01-21 |
| GB1540397A (en) | 1979-02-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |