FR2373558A1 - Nouveaux esters de spiramycine, leur preparation et la composition pharmaceutique les contenant - Google Patents

Nouveaux esters de spiramycine, leur preparation et la composition pharmaceutique les contenant

Info

Publication number
FR2373558A1
FR2373558A1 FR7736836A FR7736836A FR2373558A1 FR 2373558 A1 FR2373558 A1 FR 2373558A1 FR 7736836 A FR7736836 A FR 7736836A FR 7736836 A FR7736836 A FR 7736836A FR 2373558 A1 FR2373558 A1 FR 2373558A1
Authority
FR
France
Prior art keywords
spiramycin
esters
preparation
new
pharmaceutical composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7736836A
Other languages
English (en)
Other versions
FR2373558B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
May and Baker Ltd
Original Assignee
May and Baker Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by May and Baker Ltd filed Critical May and Baker Ltd
Publication of FR2373558A1 publication Critical patent/FR2373558A1/fr
Application granted granted Critical
Publication of FR2373558B1 publication Critical patent/FR2373558B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

L'invention a trait à de nouveaux esters de spiramycine, de formule ci-dessous dans laquelle R**1 = H, acétyle ou propionyle, A = buténylène ou butadiénylène avec doubles liaisons trans, et R**2 = -COZCOYR**3 (Z = alcoylène, Y = S ou 0, R**3 = alcoyle, cycloalcoyle, aryle ou aralcoyle), et à leurs sels d'addition d'acide. Applications comme antibiotiques contre Staphylococcus aureus, les pneumocoques, les streptocoques, en médecine vétérinaire pour traiter la mycoplasmose, et comme facteurs de stimulation de croissance pour les animaux.
FR7736836A 1976-12-08 1977-12-07 Nouveaux esters de spiramycine, leur preparation et la composition pharmaceutique les contenant Granted FR2373558A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB51257/76A GB1540397A (en) 1976-12-08 1976-12-08 Spiramycin esters

Publications (2)

Publication Number Publication Date
FR2373558A1 true FR2373558A1 (fr) 1978-07-07
FR2373558B1 FR2373558B1 (fr) 1980-04-25

Family

ID=10459281

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7736836A Granted FR2373558A1 (fr) 1976-12-08 1977-12-07 Nouveaux esters de spiramycine, leur preparation et la composition pharmaceutique les contenant

Country Status (7)

Country Link
US (1) US4174391A (fr)
JP (1) JPS5371092A (fr)
BE (1) BE861603A (fr)
DE (1) DE2754323A1 (fr)
FR (1) FR2373558A1 (fr)
GB (1) GB1540397A (fr)
NL (1) NL7713320A (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2029147B1 (fr) 2006-06-12 2010-05-19 Ramot at Tel-Aviv University Ltd. Méthodes de traitement du cancer
CN105456283B (zh) * 2015-12-30 2018-08-28 中山大学 大环内酯类抗生素或其药用盐在制备抗手足口病药物中的应用
ES2912734T3 (es) * 2017-07-04 2022-05-27 Shenyang Fuyang Pharmaceutical Tech Co Ltd Uso de isovaleril espiramicina I o III en la preparación de fármaco para tratar y/o prevenir el tumor y fármaco

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR5537M (fr) * 1966-01-06 1967-11-13

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB785191A (en) * 1955-04-13 1957-10-23 Rhone Poulenc Sa Hydrogenated spiramycins
GB796311A (en) * 1955-12-01 1958-06-11 Rhone Poulenc Sa Improvements in or relating to esters of spiramycins
US3000786A (en) * 1957-06-14 1961-09-19 Ciba Pharm Prod Inc Process for making tetrahydro-spiramycin a
FR2100881A1 (fr) * 1970-07-09 1972-03-24 Kyowa Hakko Kogyo Kk

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR5537M (fr) * 1966-01-06 1967-11-13

Also Published As

Publication number Publication date
NL7713320A (nl) 1978-06-12
DE2754323A1 (de) 1978-06-15
FR2373558B1 (fr) 1980-04-25
GB1540397A (en) 1979-02-14
JPS6131114B2 (fr) 1986-07-17
JPS5371092A (en) 1978-06-24
BE861603A (fr) 1978-06-07
US4174391A (en) 1979-11-13
DE2754323C2 (fr) 1988-01-21

Similar Documents

Publication Publication Date Title
BE836672A (fr) Procede de preparation d'acides organiques par hydrolyse biologique
FR2293928A1 (fr) Nouveaux derives d'acide 3-amino-indazolecarboxylique, leur procede de preparation et medicament les contenant
BE828666A (fr) Procede pour la preparation d'une preparation pharmaceutique contenant du zinc convenant pour emplois medicaux
BE818989A (fr) Amides n -(1-(omega)-phenylalcoyl-piperidyl-4)-n -(alpha -pyriyl)- carboxyliques, leurs sels d'addition d'acide, leur procede de preparation et leur application comme medicaments
FR2411839B1 (fr) Derives de l'acide cephalosporanique, procedes pour leur preparation et composition pharmaceutique les contenant
FR2650504B1 (fr) Hydrochlorure monohydrate de l'ester ethylique de l'acide 6-bromo-5-hydroxy-4-dimethylaminomethyl-1-methyl-2-phenylthiomethylindole-3-carbonique, procede pour son obtention et medicament antiviral comprenant ce produit
FR2373558A1 (fr) Nouveaux esters de spiramycine, leur preparation et la composition pharmaceutique les contenant
BE819294A (fr) Nouvelles compositions pharmaceutiques contenant de l'acide n-(2-furfuryl)-4-chloro-5-sulfamoyl-antranilique et leur procede de preparation
FR2450820A1 (fr) Nouveaux derives d'acides 1- (o-mercaptoacyl) -4,5-dihydropyrazole-5-carboxyliques, utiles notamment comme agents hypotenseurs, et leur procede de preparation
FR2384779A1 (fr) Nouvelles oximes derivees de l'acide 3-chloro ou 3-methoxy 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
FR2490491B1 (fr) Composition pharmaceutique analgesique contenant comme ingredient actif l'acide 3-amino-2-hydroxy-4 phenylbutanoique et ses derives et application
FR2343730A1 (fr) Derives d'acide amidinoformique ou d'acide amidinosulfinique, leur preparation et compositions pharmaceutiques les contenant
FR2515175B1 (fr) Nouveaux derives de l'acide 4-phenyl 4-oxo 2-butenoique, leurs sels, leur preparation, leur application comme medicaments et les compositions les renfermant
BE823770A (fr) Procede de preparation d'o-esters de l'acide thiocarbamique
PT84312A (fr) Procede de preparation de nouveaux derives du cyano-2 benzimidazole de compositions fungicides les contenant et de leurs associations avec d:autres fongicides
BE878836A (fr) Derives d'acide hydroxamique, leur procede de preparation et medicament les contenant
DK14490A (da) Joderede estere
FR2451918A1 (fr) Composes de 6-aryl pyrimidine, leur preparation et leur utilisation comme medicament
FR2470110B1 (fr) Derives de la decrapenylamine, leurs sels acides d'addition et composition pharmaceutique renfermant ces produits
PT67623B (pt) Procede pour la preparation d'une composition pharmaceutique contenant des nouveaux composes organiques
FR2655989B1 (fr) Nouveaux derives d'amino-acides substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
FR2315917A1 (fr) Nouveaux sels d'acide 2-p-chlorophenoxy-2-methyl-propionique d'aminoacides basiques, leur procede de preparation et medicament les contenant
BE864027A (fr) Procede de preparation de l'alpha-2,5,9-trimethylbenzo-(b)-thieno-(2,3,f)-morphane, produit obtenu et composition pharmaceutique le contenant
BE788152A (fr) Thiadiazoles utilisables pour la desinfection des semences et comme medicament antiseptique
FR2316928A1 (fr) Acide 2,4,6-triiodo-5-methoxyacetamido-n-methylisophtalamique et ses derives et composition pharmaceutique les contenant

Legal Events

Date Code Title Description
ST Notification of lapse