FR2365582A1 - Procede pour stabiliser des compositions contenant des peroxydases - Google Patents
Procede pour stabiliser des compositions contenant des peroxydasesInfo
- Publication number
- FR2365582A1 FR2365582A1 FR7728433A FR7728433A FR2365582A1 FR 2365582 A1 FR2365582 A1 FR 2365582A1 FR 7728433 A FR7728433 A FR 7728433A FR 7728433 A FR7728433 A FR 7728433A FR 2365582 A1 FR2365582 A1 FR 2365582A1
- Authority
- FR
- France
- Prior art keywords
- compositions containing
- stabilizing compositions
- peroxidase
- containing peroxidases
- peroxidases
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
- C12Q1/28—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving peroxidase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/44—Oxidoreductases (1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y111/00—Oxidoreductases acting on a peroxide as acceptor (1.11)
- C12Y111/01—Peroxidases (1.11.1)
- C12Y111/01017—Glutathione amide-dependent peroxidase (1.11.1.17)
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/963—Methods of stopping an enzyme reaction or stabilizing the test materials
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Enzymes And Modification Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
L'invention concerne un procédé pour stabiliser des compositions renfermant une peroxydase. On stabilise des compositions contenant une peroxydase en ajoutant comme stabilisant un ion métallique polyvalent et éventuellement également un agent séquestrant L'invention s'applique en particulier à des compositions lyophilisées servant à effectuer des déterminations immunologiques.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NL7610608A NL7610608A (nl) | 1976-09-24 | 1976-09-24 | Werkwijze voor het stabiliseren van peroxidase- -bevattende composities. |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2365582A1 true FR2365582A1 (fr) | 1978-04-21 |
FR2365582B1 FR2365582B1 (fr) | 1980-05-16 |
Family
ID=19826964
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7728433A Granted FR2365582A1 (fr) | 1976-09-24 | 1977-09-21 | Procede pour stabiliser des compositions contenant des peroxydases |
Country Status (17)
Country | Link |
---|---|
US (3) | US4169012A (fr) |
JP (1) | JPS5352686A (fr) |
AU (1) | AU519391B2 (fr) |
BE (1) | BE859007A (fr) |
CA (1) | CA1098824A (fr) |
CH (1) | CH629851A5 (fr) |
DE (1) | DE2742699A1 (fr) |
DK (1) | DK417877A (fr) |
ES (1) | ES462576A1 (fr) |
FI (1) | FI772747A (fr) |
FR (1) | FR2365582A1 (fr) |
GB (1) | GB1592371A (fr) |
HU (1) | HU175006B (fr) |
IT (1) | IT1090003B (fr) |
NL (1) | NL7610608A (fr) |
SE (1) | SE428608B (fr) |
ZA (1) | ZA775392B (fr) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2472609A1 (fr) * | 1979-12-28 | 1981-07-03 | Green Cross Corp | Procede pour separer la myeloperoxydase et composition pharmaceutique contenant de la myeloperoxydase |
EP0098073A2 (fr) * | 1982-06-25 | 1984-01-11 | Green Cross Corporation | Composition pharmaceutique en poudre, contenant de la myéloperoxidase |
Families Citing this family (63)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL7610608A (nl) * | 1976-09-24 | 1978-03-29 | Akzo Nv | Werkwijze voor het stabiliseren van peroxidase- -bevattende composities. |
DE2831580C2 (de) * | 1978-07-18 | 1980-09-18 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verfahren und Reagens zur Bestimmung von Glycerin |
JPS5549801U (fr) * | 1978-09-19 | 1980-04-01 | ||
JPS5554895A (en) * | 1978-10-16 | 1980-04-22 | Sanyo Chem Ind Ltd | Stable peroxidase-containing composition |
US4289748A (en) * | 1979-05-31 | 1981-09-15 | United States Of America | Ultrasensitive enzymatic radioimmunoassay method |
US4234680A (en) * | 1979-08-03 | 1980-11-18 | Calbiochem-Behring Corp. | Method for terminating a peroxidase catalyzed reaction |
US4282316A (en) * | 1979-09-11 | 1981-08-04 | Modrovich Ivan Endre | Stabilized enzymic solutions for determining urea |
US4465770A (en) * | 1979-09-11 | 1984-08-14 | Modrovich Ivan Endre | Stabilized enzymic solutions for determining urea |
US4378430A (en) * | 1979-09-11 | 1983-03-29 | Modrovich Ivan Endre | Method of forming stabilized urease solutions |
US4252896A (en) * | 1980-01-07 | 1981-02-24 | Abbott Laboratories | Method of stabilizing peroxidase in a serum protein based medium |
GB2070767B (en) * | 1980-03-03 | 1983-07-27 | Abbott Lab | Stabilizing the reaction product formed in enzyme immunoassays |
US4310626A (en) * | 1980-06-02 | 1982-01-12 | Miles Laboratories, Inc. | Interference-resistant composition, device and method for determining a peroxidatively active substance in a test sample |
US4447527A (en) * | 1980-09-02 | 1984-05-08 | Syva Company | Single test formulations for enzyme immunoassays and method for preparation |
US4350659A (en) * | 1981-07-30 | 1982-09-21 | Corning Glass Works | Stabilization of sensitive biologically active intermediate metabolites such as folic acid derivatives |
US4578265A (en) * | 1981-08-13 | 1986-03-25 | Laclede Professional Products, Inc. | Di-enzymatic dentifrice |
US4419453A (en) * | 1981-09-28 | 1983-12-06 | The Dow Chemical Company | Immunological agglutination assays with dyed or colored latex and kits |
US4454226A (en) * | 1982-03-17 | 1984-06-12 | Majid Ali | Enzymatic immunoassay |
US4587220A (en) * | 1983-03-28 | 1986-05-06 | Miles Laboratories, Inc. | Ascorbate interference-resistant composition, device and method for the determination of peroxidatively active substances |
DE3315389A1 (de) * | 1983-04-28 | 1984-10-31 | Flemming GmbH, 6204 Taunusstein | Verfahren und mittel zur quantitativen bestimmung von wasserstoffperoxid und deren anwendung |
JPS59205999A (ja) * | 1983-05-10 | 1984-11-21 | Wako Pure Chem Ind Ltd | 還元型補酵素の定量方法 |
JPS59230161A (ja) * | 1983-06-13 | 1984-12-24 | Wako Pure Chem Ind Ltd | 還元性物質の分解方法及び分解用試薬 |
US4615972A (en) * | 1983-11-04 | 1986-10-07 | Immuno Concepts, Inc. | Stabilization of indicators for detecting enzyme activity |
US4891311A (en) * | 1984-02-03 | 1990-01-02 | Abbott Laboratories | Stabilized enzyme conjugate composition |
JPS60162957A (ja) * | 1984-02-03 | 1985-08-24 | Kyowa Medetsukusu Kk | セルロプラスミン活性の測定法 |
DD247808C2 (de) * | 1984-04-09 | 1989-01-11 | Dresden Arzneimittel | Teststreifen zur aufnahme von blutzuckertagesprofilen und verfahren zu seiner herstellung |
JPH0614879B2 (ja) * | 1984-04-27 | 1994-03-02 | 株式会社ヤトロン | ビリルビンの干渉を回避して行なう生体成分の測定方法 |
DK8502857A (fr) * | 1984-06-25 | 1985-12-26 | ||
US4686182A (en) * | 1984-10-17 | 1987-08-11 | Minnesota Mining And Manufacturing Company | Method and kit for detecting antibiotics in a liquid sample |
EP0196743A3 (fr) * | 1985-01-31 | 1988-10-19 | Savyon Diagnostics Ltd. | Compositions chimiques stables contenant des matériaux chromogènes et des peroxydes et procédé pour leur obtention |
JPS62502653A (ja) * | 1985-02-11 | 1987-10-15 | トラベノ−ル‐ジエネンテツク、ダイアグノスチクス | 安定化された酵素基質溶液 |
DE3511327A1 (de) * | 1985-03-28 | 1986-10-02 | Boehringer Mannheim Gmbh, 6800 Mannheim | Stabilisierung der aktivitaet von peroxidase in loesung |
US4824784A (en) * | 1985-04-08 | 1989-04-25 | Hygeia Sciences, Incorporated | Chromogenic solution for immunoassay |
US4931385A (en) * | 1985-06-24 | 1990-06-05 | Hygeia Sciences, Incorporated | Enzyme immunoassays and immunologic reagents |
US4868108A (en) * | 1985-12-12 | 1989-09-19 | Hygeia Sciences, Incorporated | Multiple-antibody detection of antigen |
US4897353A (en) * | 1986-03-13 | 1990-01-30 | University Of Southwestern Louisiana | Cryogenic protection of phosphofructokinase using amino acids and zinc ions |
US4806343A (en) * | 1986-03-13 | 1989-02-21 | University Of Southwestern Louisiana | Cryogenic protectant for proteins |
US5155024A (en) * | 1986-07-10 | 1992-10-13 | Eastman Kodak Company | Binder composition and analytical element having stabilized peroxidase in layer containing the composition |
US4897346A (en) * | 1986-07-15 | 1990-01-30 | Beckman Instruments, Inc. | Stabilized liquid enzyme composition for glucose determination |
US5177192A (en) * | 1987-04-02 | 1993-01-05 | Centocor, Incorporated | Method for labeling antibodies with a metal ion |
US4874692A (en) * | 1987-07-20 | 1989-10-17 | Eastman Kodak Company | Binder composition and analytical element having stabilized peroxidase in layer containing the composition |
US5102788A (en) * | 1988-11-21 | 1992-04-07 | Hygeia Sciences, Inc. | Immunoassay including lyophilized reactant mixture |
US4992372A (en) * | 1989-02-02 | 1991-02-12 | Pokora Alexander R | Method for removing impurities from peroxidase solutions |
US5308604A (en) * | 1989-04-19 | 1994-05-03 | Deutsches Krebsforschungsinstitut | Conjugates for tumor localization and/or tumor therapy |
US5318894A (en) * | 1990-01-30 | 1994-06-07 | Miles Inc. | Composition, device and method of assaying for peroxidatively active substances |
US5468622A (en) * | 1990-04-03 | 1995-11-21 | Immunomatrix, Inc. | Salt stabilization of antibody-enzyme conjugates heat-dried into paper |
DE4103220A1 (de) * | 1991-02-02 | 1992-08-06 | Boehringer Mannheim Gmbh | Verfahren zur stabilisierung von 1-methylhydantoinase, verwendung einer stabilisierten 1-methylhydantoinase zur bestimmung eines analyten, entsprechendes bestimmungsverfahren sowie hierfuer geeignete mittel |
US5491085A (en) * | 1991-05-14 | 1996-02-13 | Enzymol International, Inc. | Method of recovering peroxidase from seed hulls using a freeze-thaw technique |
US5460944A (en) * | 1991-10-28 | 1995-10-24 | Boehringer Mannheim Gmbh | Storable protein solution |
DE4135542A1 (de) | 1991-10-28 | 1993-04-29 | Boehringer Mannheim Gmbh | Lagerfaehige proteinloesungen |
WO1993011226A1 (fr) * | 1991-11-27 | 1993-06-10 | Novo Nordisk A/S | Activation d'une peroxydase ou d'une haloperoxydase |
CA2114163C (fr) * | 1993-01-29 | 2002-04-30 | Nobuo Nishiki | Methode de stabilisation de l'antigenicite de la myeloperoxydase |
US5696193A (en) * | 1994-04-25 | 1997-12-09 | Clinical Diagnostic Systems, Inc. | Immunoassay elements comprising polymers containing vandium IV (V+4) ions |
US5516645A (en) * | 1994-04-25 | 1996-05-14 | Johnson & Johnson Clinical Diagnostics, Inc. | Immunoassay analytical elements containing vanadium IV(V+4)ions |
US5962340A (en) * | 1994-11-02 | 1999-10-05 | Wako Pure Chemical Industries Ltd. | Homogeneous immunoassay method utilizing 5-300 mM magnesium |
US5928886A (en) * | 1995-06-07 | 1999-07-27 | Johnson & Johnson Clinical Diagnostics, Inc. | Reduction in first slide bias and improved enzyme stability by incorporation of diaryl tellurides in the gravure layer of dry-film, immunoassay elements |
US5686254A (en) * | 1995-06-07 | 1997-11-11 | Johnson & Johnson Clinical Diagnostics, Inc. | Reduction in first slide bias and improved enzyme stability by the incorporation of diaryl tellurides in thin-film immunoassay elements |
NL1007085C2 (nl) * | 1997-09-19 | 1999-03-22 | Inst Voor Agrotech Onderzoek | Werkwijze voor de oxidatie van koolhydraten. |
US6753159B1 (en) | 1998-08-06 | 2004-06-22 | Jin Po Lee | Uric acid assay device with stabilized uricase reagent composition |
EP1030931A4 (fr) * | 1998-08-06 | 2004-05-26 | Syntron Biores Inc | Dispositif de test d'acide urique presentant une composition reactive d'uricase stabilisee |
US6500629B1 (en) | 1999-09-13 | 2002-12-31 | Equitech Laboratories, Inc. | Materials and methods for detection and quantitation of an analyte |
US20040178714A1 (en) * | 2003-03-11 | 2004-09-16 | Pan Wun Fang | Decorative bulb of a series connected light string |
WO2008043041A1 (fr) | 2006-10-04 | 2008-04-10 | University Of Washington | Procédé et dispositif permettant des analyses par affinité moléculaire microfluidique parallèle rapide |
EP2584044B1 (fr) | 2007-07-26 | 2015-04-22 | Agamatrix, Inc. | Appareil de détection d'analyte électrochimique et procédé |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB626848A (en) | 1945-11-21 | 1949-07-22 | Dwight Lynds Baker | Method of and means for protecting foodstuffs from the deleterious action of free oxygen |
US3019171A (en) * | 1957-11-25 | 1962-01-30 | Ethicon Inc | Activated enzyme compositions |
US3005714A (en) * | 1959-08-26 | 1961-10-24 | Univ Northwestern | Galactose oxidase |
US2990338A (en) * | 1959-11-24 | 1961-06-27 | Gibson Jacob John | Composition for determination of glucose in body fluids |
US3371081A (en) | 1963-08-29 | 1968-02-27 | Sankyo Co | Process for the purification of cytochrome c |
US3367842A (en) * | 1965-02-17 | 1968-02-06 | Miles Lab | Test composition and device for the detection of galactose in fluids |
US3413198A (en) * | 1966-06-30 | 1968-11-26 | Calbiochem | Reagents and method for assaying biological samples |
USRE29169E (en) | 1971-02-10 | 1977-04-05 | Akzona Incorporated | Process for the demonstration and determination of reaction components having specific binding affinity for each other |
GB1293227A (en) | 1970-02-18 | 1972-10-18 | Squibb & Sons Inc | Process for the production of antimicrobial agents |
US3953295A (en) * | 1971-10-20 | 1976-04-27 | Mallinckrodt, Inc. | Reagent formulations for glucose assay |
GB1447751A (en) * | 1972-09-06 | 1976-09-02 | Gist Brocades Nv | Chelates of nitrogen-containing organic substances |
US3947324A (en) * | 1975-04-21 | 1976-03-30 | G. D. Searle And Co. | Method for isolating high purity peroxidase |
NL7610608A (nl) * | 1976-09-24 | 1978-03-29 | Akzo Nv | Werkwijze voor het stabiliseren van peroxidase- -bevattende composities. |
-
1976
- 1976-09-24 NL NL7610608A patent/NL7610608A/xx not_active Application Discontinuation
-
1977
- 1977-09-07 GB GB37326/77A patent/GB1592371A/en not_active Expired
- 1977-09-07 ZA ZA00775392A patent/ZA775392B/xx unknown
- 1977-09-09 US US05/831,817 patent/US4169012A/en not_active Expired - Lifetime
- 1977-09-12 AU AU28717/77A patent/AU519391B2/en not_active Expired
- 1977-09-19 FI FI772747A patent/FI772747A/fi not_active Application Discontinuation
- 1977-09-19 CH CH1141677A patent/CH629851A5/de not_active IP Right Cessation
- 1977-09-21 DK DK417877A patent/DK417877A/da not_active Application Discontinuation
- 1977-09-21 FR FR7728433A patent/FR2365582A1/fr active Granted
- 1977-09-22 JP JP11450777A patent/JPS5352686A/ja active Pending
- 1977-09-22 IT IT51120/77A patent/IT1090003B/it active
- 1977-09-22 DE DE19772742699 patent/DE2742699A1/de not_active Withdrawn
- 1977-09-23 BE BE181164A patent/BE859007A/fr unknown
- 1977-09-23 ES ES462576A patent/ES462576A1/es not_active Expired
- 1977-09-23 CA CA287,392A patent/CA1098824A/fr not_active Expired
- 1977-09-23 HU HU77AO451A patent/HU175006B/hu unknown
- 1977-09-23 SE SE7710678A patent/SE428608B/xx unknown
-
1979
- 1979-01-25 US US06/006,934 patent/US4228240A/en not_active Expired - Lifetime
-
1980
- 1980-01-04 US US06/109,627 patent/US4331761A/en not_active Expired - Lifetime
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2472609A1 (fr) * | 1979-12-28 | 1981-07-03 | Green Cross Corp | Procede pour separer la myeloperoxydase et composition pharmaceutique contenant de la myeloperoxydase |
EP0098073A2 (fr) * | 1982-06-25 | 1984-01-11 | Green Cross Corporation | Composition pharmaceutique en poudre, contenant de la myéloperoxidase |
EP0098073A3 (en) * | 1982-06-25 | 1985-09-25 | The Green Cross Corporation | Powdery pharmaceutical composition of myeloperoxidase |
Also Published As
Publication number | Publication date |
---|---|
CA1098824A (fr) | 1981-04-07 |
BE859007A (fr) | 1978-03-23 |
DE2742699A1 (de) | 1978-03-30 |
US4228240A (en) | 1980-10-14 |
FR2365582B1 (fr) | 1980-05-16 |
AU519391B2 (en) | 1981-12-03 |
US4169012A (en) | 1979-09-25 |
GB1592371A (en) | 1981-07-08 |
JPS5352686A (en) | 1978-05-13 |
AU2871777A (en) | 1979-03-22 |
FI772747A (fi) | 1978-03-25 |
DK417877A (da) | 1978-03-25 |
ZA775392B (en) | 1978-07-26 |
NL7610608A (nl) | 1978-03-29 |
HU175006B (hu) | 1980-04-28 |
US4331761A (en) | 1982-05-25 |
SE428608B (sv) | 1983-07-11 |
SE7710678L (sv) | 1978-03-25 |
CH629851A5 (de) | 1982-05-14 |
ES462576A1 (es) | 1978-12-01 |
IT1090003B (it) | 1985-06-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |