ES462576A1 - Procedimiento para la estabilizacion de composiciones que contienen peroxidas. - Google Patents

Procedimiento para la estabilizacion de composiciones que contienen peroxidas.

Info

Publication number
ES462576A1
ES462576A1 ES462576A ES462576A ES462576A1 ES 462576 A1 ES462576 A1 ES 462576A1 ES 462576 A ES462576 A ES 462576A ES 462576 A ES462576 A ES 462576A ES 462576 A1 ES462576 A1 ES 462576A1
Authority
ES
Spain
Prior art keywords
enzyme immunoassay
peroxidase reagent
compositions
novel
stabilized peroxidase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES462576A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Akzo NV
Original Assignee
Akzo NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo NV filed Critical Akzo NV
Publication of ES462576A1 publication Critical patent/ES462576A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/28—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving peroxidase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/44—Oxidoreductases (1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y111/00—Oxidoreductases acting on a peroxide as acceptor (1.11)
    • C12Y111/01—Peroxidases (1.11.1)
    • C12Y111/01017—Glutathione amide-dependent peroxidase (1.11.1.17)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/963—Methods of stopping an enzyme reaction or stabilizing the test materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Procedimiento para la estabilización de composiciones que contienen peroxidasa, que comprende añadir a una composición de esta naturaleza un ión de metal polivalente, preferiblemente en forma de una sal, en una cantidad de 1 nanogramo a 25 microgramos por mililitro, después de lo cual se puede liofilizar la composición.
ES462576A 1976-09-24 1977-09-23 Procedimiento para la estabilizacion de composiciones que contienen peroxidas. Expired ES462576A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL7610608A NL7610608A (nl) 1976-09-24 1976-09-24 Werkwijze voor het stabiliseren van peroxidase- -bevattende composities.

Publications (1)

Publication Number Publication Date
ES462576A1 true ES462576A1 (es) 1978-12-01

Family

ID=19826964

Family Applications (1)

Application Number Title Priority Date Filing Date
ES462576A Expired ES462576A1 (es) 1976-09-24 1977-09-23 Procedimiento para la estabilizacion de composiciones que contienen peroxidas.

Country Status (17)

Country Link
US (3) US4169012A (es)
JP (1) JPS5352686A (es)
AU (1) AU519391B2 (es)
BE (1) BE859007A (es)
CA (1) CA1098824A (es)
CH (1) CH629851A5 (es)
DE (1) DE2742699A1 (es)
DK (1) DK417877A (es)
ES (1) ES462576A1 (es)
FI (1) FI772747A (es)
FR (1) FR2365582A1 (es)
GB (1) GB1592371A (es)
HU (1) HU175006B (es)
IT (1) IT1090003B (es)
NL (1) NL7610608A (es)
SE (1) SE428608B (es)
ZA (1) ZA775392B (es)

Families Citing this family (65)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7610608A (nl) * 1976-09-24 1978-03-29 Akzo Nv Werkwijze voor het stabiliseren van peroxidase- -bevattende composities.
DE2831580C2 (de) * 1978-07-18 1980-09-18 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren und Reagens zur Bestimmung von Glycerin
JPS5549801U (es) * 1978-09-19 1980-04-01
JPS5554895A (en) * 1978-10-16 1980-04-22 Sanyo Chem Ind Ltd Stable peroxidase-containing composition
US4289748A (en) * 1979-05-31 1981-09-15 United States Of America Ultrasensitive enzymatic radioimmunoassay method
US4234680A (en) * 1979-08-03 1980-11-18 Calbiochem-Behring Corp. Method for terminating a peroxidase catalyzed reaction
US4282316A (en) * 1979-09-11 1981-08-04 Modrovich Ivan Endre Stabilized enzymic solutions for determining urea
US4465770A (en) * 1979-09-11 1984-08-14 Modrovich Ivan Endre Stabilized enzymic solutions for determining urea
US4378430A (en) * 1979-09-11 1983-03-29 Modrovich Ivan Endre Method of forming stabilized urease solutions
SE448882B (sv) * 1979-12-28 1987-03-23 Green Cross Corp Forfarande for utvinning av myeloperoxidas och farmaceutisk komposition innehallande enzymet
US4252896A (en) * 1980-01-07 1981-02-24 Abbott Laboratories Method of stabilizing peroxidase in a serum protein based medium
GB2070767B (en) * 1980-03-03 1983-07-27 Abbott Lab Stabilizing the reaction product formed in enzyme immunoassays
US4310626A (en) * 1980-06-02 1982-01-12 Miles Laboratories, Inc. Interference-resistant composition, device and method for determining a peroxidatively active substance in a test sample
US4447527A (en) * 1980-09-02 1984-05-08 Syva Company Single test formulations for enzyme immunoassays and method for preparation
US4350659A (en) * 1981-07-30 1982-09-21 Corning Glass Works Stabilization of sensitive biologically active intermediate metabolites such as folic acid derivatives
US4578265A (en) * 1981-08-13 1986-03-25 Laclede Professional Products, Inc. Di-enzymatic dentifrice
US4419453A (en) * 1981-09-28 1983-12-06 The Dow Chemical Company Immunological agglutination assays with dyed or colored latex and kits
US4454226A (en) * 1982-03-17 1984-06-12 Majid Ali Enzymatic immunoassay
JPS592686A (ja) * 1982-06-25 1984-01-09 Green Cross Corp:The ミエロペルオキシダ−ゼの粉末製剤
US4587220A (en) * 1983-03-28 1986-05-06 Miles Laboratories, Inc. Ascorbate interference-resistant composition, device and method for the determination of peroxidatively active substances
DE3315389A1 (de) * 1983-04-28 1984-10-31 Flemming GmbH, 6204 Taunusstein Verfahren und mittel zur quantitativen bestimmung von wasserstoffperoxid und deren anwendung
JPS59205999A (ja) * 1983-05-10 1984-11-21 Wako Pure Chem Ind Ltd 還元型補酵素の定量方法
JPS59230161A (ja) * 1983-06-13 1984-12-24 Wako Pure Chem Ind Ltd 還元性物質の分解方法及び分解用試薬
US4615972A (en) * 1983-11-04 1986-10-07 Immuno Concepts, Inc. Stabilization of indicators for detecting enzyme activity
JPS60162957A (ja) * 1984-02-03 1985-08-24 Kyowa Medetsukusu Kk セルロプラスミン活性の測定法
US4891311A (en) * 1984-02-03 1990-01-02 Abbott Laboratories Stabilized enzyme conjugate composition
DD247808C2 (de) * 1984-04-09 1989-01-11 Dresden Arzneimittel Teststreifen zur aufnahme von blutzuckertagesprofilen und verfahren zu seiner herstellung
JPH0614879B2 (ja) * 1984-04-27 1994-03-02 株式会社ヤトロン ビリルビンの干渉を回避して行なう生体成分の測定方法
DK8502857A (es) * 1984-06-25 1985-12-26
US4686182A (en) * 1984-10-17 1987-08-11 Minnesota Mining And Manufacturing Company Method and kit for detecting antibiotics in a liquid sample
EP0196743A3 (en) * 1985-01-31 1988-10-19 Savyon Diagnostics Ltd. Stable chemical compositions containing chromogenic materials and peroxides, and method for obtaining them
WO1986004610A1 (en) * 1985-02-11 1986-08-14 Travenol-Genentech Diagnostics Stabilized enzyme substrate solutions
DE3511327A1 (de) * 1985-03-28 1986-10-02 Boehringer Mannheim Gmbh, 6800 Mannheim Stabilisierung der aktivitaet von peroxidase in loesung
US4824784A (en) * 1985-04-08 1989-04-25 Hygeia Sciences, Incorporated Chromogenic solution for immunoassay
US4931385A (en) * 1985-06-24 1990-06-05 Hygeia Sciences, Incorporated Enzyme immunoassays and immunologic reagents
US4868108A (en) * 1985-12-12 1989-09-19 Hygeia Sciences, Incorporated Multiple-antibody detection of antigen
US4806343A (en) * 1986-03-13 1989-02-21 University Of Southwestern Louisiana Cryogenic protectant for proteins
US4897353A (en) * 1986-03-13 1990-01-30 University Of Southwestern Louisiana Cryogenic protection of phosphofructokinase using amino acids and zinc ions
US5155024A (en) * 1986-07-10 1992-10-13 Eastman Kodak Company Binder composition and analytical element having stabilized peroxidase in layer containing the composition
US4897346A (en) * 1986-07-15 1990-01-30 Beckman Instruments, Inc. Stabilized liquid enzyme composition for glucose determination
US5177192A (en) * 1987-04-02 1993-01-05 Centocor, Incorporated Method for labeling antibodies with a metal ion
US4874692A (en) * 1987-07-20 1989-10-17 Eastman Kodak Company Binder composition and analytical element having stabilized peroxidase in layer containing the composition
US5102788A (en) * 1988-11-21 1992-04-07 Hygeia Sciences, Inc. Immunoassay including lyophilized reactant mixture
US4992372A (en) * 1989-02-02 1991-02-12 Pokora Alexander R Method for removing impurities from peroxidase solutions
US5308604A (en) * 1989-04-19 1994-05-03 Deutsches Krebsforschungsinstitut Conjugates for tumor localization and/or tumor therapy
US5318894A (en) * 1990-01-30 1994-06-07 Miles Inc. Composition, device and method of assaying for peroxidatively active substances
US5468622A (en) * 1990-04-03 1995-11-21 Immunomatrix, Inc. Salt stabilization of antibody-enzyme conjugates heat-dried into paper
DE4103220A1 (de) * 1991-02-02 1992-08-06 Boehringer Mannheim Gmbh Verfahren zur stabilisierung von 1-methylhydantoinase, verwendung einer stabilisierten 1-methylhydantoinase zur bestimmung eines analyten, entsprechendes bestimmungsverfahren sowie hierfuer geeignete mittel
US5491085A (en) * 1991-05-14 1996-02-13 Enzymol International, Inc. Method of recovering peroxidase from seed hulls using a freeze-thaw technique
US5460944A (en) * 1991-10-28 1995-10-24 Boehringer Mannheim Gmbh Storable protein solution
DE4135542A1 (de) * 1991-10-28 1993-04-29 Boehringer Mannheim Gmbh Lagerfaehige proteinloesungen
WO1993011226A1 (en) * 1991-11-27 1993-06-10 Novo Nordisk A/S Activation of peroxidase or haloperoxidase
CA2114163C (en) * 1993-01-29 2002-04-30 Nobuo Nishiki Method for stabilizing antigenicity of myeloperoxidase
US5516645A (en) * 1994-04-25 1996-05-14 Johnson & Johnson Clinical Diagnostics, Inc. Immunoassay analytical elements containing vanadium IV(V+4)ions
US5696193A (en) * 1994-04-25 1997-12-09 Clinical Diagnostic Systems, Inc. Immunoassay elements comprising polymers containing vandium IV (V+4) ions
US5962340A (en) * 1994-11-02 1999-10-05 Wako Pure Chemical Industries Ltd. Homogeneous immunoassay method utilizing 5-300 mM magnesium
US5928886A (en) * 1995-06-07 1999-07-27 Johnson & Johnson Clinical Diagnostics, Inc. Reduction in first slide bias and improved enzyme stability by incorporation of diaryl tellurides in the gravure layer of dry-film, immunoassay elements
US5686254A (en) * 1995-06-07 1997-11-11 Johnson & Johnson Clinical Diagnostics, Inc. Reduction in first slide bias and improved enzyme stability by the incorporation of diaryl tellurides in thin-film immunoassay elements
NL1007085C2 (nl) * 1997-09-19 1999-03-22 Inst Voor Agrotech Onderzoek Werkwijze voor de oxidatie van koolhydraten.
EP1030931A4 (en) * 1998-08-06 2004-05-26 Syntron Biores Inc URIC ACID TEST DEVICE HAVING A STABILIZED URICASE REACTIVE COMPOSITION
US6753159B1 (en) 1998-08-06 2004-06-22 Jin Po Lee Uric acid assay device with stabilized uricase reagent composition
WO2001020326A2 (en) 1999-09-13 2001-03-22 Equitech Laboratories, Inc. Materials and methods for the determination of an analyte
US20040178714A1 (en) * 2003-03-11 2004-09-16 Pan Wun Fang Decorative bulb of a series connected light string
US8101403B2 (en) 2006-10-04 2012-01-24 University Of Washington Method and device for rapid parallel microfluidic molecular affinity assays
EP2584044B1 (en) 2007-07-26 2015-04-22 Agamatrix, Inc. Electrochemical analyte detections apparatus and method

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GB626848A (en) 1945-11-21 1949-07-22 Dwight Lynds Baker Method of and means for protecting foodstuffs from the deleterious action of free oxygen
US3019171A (en) * 1957-11-25 1962-01-30 Ethicon Inc Activated enzyme compositions
US3005714A (en) * 1959-08-26 1961-10-24 Univ Northwestern Galactose oxidase
US2990338A (en) * 1959-11-24 1961-06-27 Gibson Jacob John Composition for determination of glucose in body fluids
US3371081A (en) 1963-08-29 1968-02-27 Sankyo Co Process for the purification of cytochrome c
US3367842A (en) * 1965-02-17 1968-02-06 Miles Lab Test composition and device for the detection of galactose in fluids
US3413198A (en) * 1966-06-30 1968-11-26 Calbiochem Reagents and method for assaying biological samples
USRE29169E (en) 1971-02-10 1977-04-05 Akzona Incorporated Process for the demonstration and determination of reaction components having specific binding affinity for each other
GB1293227A (en) 1970-02-18 1972-10-18 Squibb & Sons Inc Process for the production of antimicrobial agents
US3953295A (en) * 1971-10-20 1976-04-27 Mallinckrodt, Inc. Reagent formulations for glucose assay
GB1447751A (en) * 1972-09-06 1976-09-02 Gist Brocades Nv Chelates of nitrogen-containing organic substances
US3947324A (en) * 1975-04-21 1976-03-30 G. D. Searle And Co. Method for isolating high purity peroxidase
NL7610608A (nl) * 1976-09-24 1978-03-29 Akzo Nv Werkwijze voor het stabiliseren van peroxidase- -bevattende composities.

Also Published As

Publication number Publication date
US4331761A (en) 1982-05-25
SE428608B (sv) 1983-07-11
AU519391B2 (en) 1981-12-03
FI772747A (fi) 1978-03-25
ZA775392B (en) 1978-07-26
JPS5352686A (en) 1978-05-13
NL7610608A (nl) 1978-03-29
IT1090003B (it) 1985-06-18
GB1592371A (en) 1981-07-08
DK417877A (da) 1978-03-25
CH629851A5 (de) 1982-05-14
CA1098824A (en) 1981-04-07
HU175006B (hu) 1980-04-28
FR2365582A1 (fr) 1978-04-21
DE2742699A1 (de) 1978-03-30
AU2871777A (en) 1979-03-22
US4228240A (en) 1980-10-14
BE859007A (fr) 1978-03-23
US4169012A (en) 1979-09-25
SE7710678L (sv) 1978-03-25
FR2365582B1 (es) 1980-05-16

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