FR2365124A1 - Procede et appareillage pour la detection d'une proteine de fixation specifique ou d'une substance capable de se livrer sur cette proteine - Google Patents

Procede et appareillage pour la detection d'une proteine de fixation specifique ou d'une substance capable de se livrer sur cette proteine

Info

Publication number
FR2365124A1
FR2365124A1 FR7728226A FR7728226A FR2365124A1 FR 2365124 A1 FR2365124 A1 FR 2365124A1 FR 7728226 A FR7728226 A FR 7728226A FR 7728226 A FR7728226 A FR 7728226A FR 2365124 A1 FR2365124 A1 FR 2365124A1
Authority
FR
France
Prior art keywords
protein
detection
specific binding
substance capable
delivery
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7728226A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB3901876A external-priority patent/GB1573627A/en
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Publication of FR2365124A1 publication Critical patent/FR2365124A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/78Thyroid gland hormones, e.g. T3, T4, TBH, TBG or their receptors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/80Fluorescent dyes, e.g. rhodamine
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/804Radioisotope, e.g. radioimmunoassay
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/807Apparatus included in process claim, e.g. physical support structures
    • Y10S436/808Automated or kit
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/826Additives, e.g. buffers, diluents, preservatives

Abstract

Procédé et appareillage pour la détection et le dosage d'un composant de la réaction entre une protéine de fixation spécifique et la substance correspondante capable de fixer sur cette protéine. On envoie dans un courant de liquide contenu successivement des mélanges de la matière à analyser avec une quantité déterminée d'un composant de la réaction sous forme marquée et d'un autre composant fixé sur un support en particules insolubles ou convertibles en particules insolubles en veillant à ce que les mélanges individuels restent séparés, et on mesure la quantité du composé marqué contenu dans l'une des phases séparées.
FR7728226A 1976-09-18 1977-09-19 Procede et appareillage pour la detection d'une proteine de fixation specifique ou d'une substance capable de se livrer sur cette proteine Withdrawn FR2365124A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB3901876A GB1573627A (en) 1976-09-18 1976-09-18 Process and device for the determination and detection of a reaction component
DE19772736527 DE2736527A1 (de) 1976-09-18 1977-08-12 Verfahren und vorrichtung zum nachweis eines spezifischen bindeproteins oder einer damit bindefaehigen substanz

Publications (1)

Publication Number Publication Date
FR2365124A1 true FR2365124A1 (fr) 1978-04-14

Family

ID=25772520

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7728226A Withdrawn FR2365124A1 (fr) 1976-09-18 1977-09-19 Procede et appareillage pour la detection d'une proteine de fixation specifique ou d'une substance capable de se livrer sur cette proteine

Country Status (8)

Country Link
US (1) US4251360A (fr)
JP (1) JPS5366418A (fr)
AT (1) AT357272B (fr)
AU (1) AU513350B2 (fr)
ES (1) ES462365A1 (fr)
FR (1) FR2365124A1 (fr)
IT (1) IT1087524B (fr)
NL (1) NL7710018A (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0054675A1 (fr) * 1980-12-23 1982-06-30 Roche Diagnostics GmbH Procédé de détermination immunoenzymatique en phase hétérogène
EP0210107A1 (fr) * 1985-07-26 1987-01-28 Lyonnaise Des Eaux - Dumez Procédé de dosage immunologique en continu de composés organiques dans un fluide en circulation, et dispositif de mise en oeuvre

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4567150A (en) * 1981-11-20 1986-01-28 Sclavo, S.P.A. Method for determining transferrin and composition therefor
US4895809A (en) * 1984-01-09 1990-01-23 Varian Associates, Inc. Immobilized antigen-antibody displacement process
JPH0665989B2 (ja) * 1984-12-03 1994-08-24 オリンパス光学工業株式会社 免疫学的分析方法
JPS6324161A (ja) * 1987-03-18 1988-02-01 Olympus Optical Co Ltd 酵素免疫自動測定機における結合物質と非結合物質との分離方法
US5045479A (en) * 1988-07-05 1991-09-03 The Johns Hopkins University Continuous flow competitive assay with reference system
US5198340A (en) * 1991-01-17 1993-03-30 Genentech, Inc. Assay for free igf-i, igf-ii, and gh levels in body fluids
US6150123A (en) * 1998-09-03 2000-11-21 Centre Integre De Recherches Biocliniques Sur Le Sida (Cirbs) Affinity biotinylation
US7905433B2 (en) * 2007-06-20 2011-03-15 New Jersey Institute Of Technology Systems and methods for reducing electrostatic charge in a fluidized bed

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2797149A (en) * 1953-01-08 1957-06-25 Technicon International Ltd Methods of and apparatus for analyzing liquids containing crystalloid and non-crystalloid constituents
DE1523058A1 (de) * 1962-09-05 1968-12-12 Technicon Instr Verfahren und Vorrichtung zum Feststellen,welche einer Anzahl von Blutproben mit einem bestimmten Stoff eine Agglutinationsreaktion eingehen
US3896217A (en) * 1973-03-19 1975-07-22 Summa Corp Method and apparatus for radioimmunoassay with regeneration of immunoadsorbent
US3925018A (en) * 1973-06-08 1975-12-09 Technicon Instr Method and apparatus for quantitative analysis utilizing particulate reagent material
GB1420916A (en) * 1971-09-08 1976-01-14 Bagshawe K D Performance of chemical or biological reactions

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3203865A (en) * 1962-11-30 1965-08-31 Dow Chemical Co Hog serum antibody concentrate
US3268441A (en) * 1963-05-21 1966-08-23 Ionics Water recovery by electrodialysis
US3901654A (en) * 1971-06-21 1975-08-26 Biological Developments Receptor assays of biologically active compounds employing biologically specific receptors
FR2225509B1 (fr) * 1973-04-12 1976-05-21 Inst Francais Du Petrole
CH566798A5 (fr) * 1973-05-29 1975-09-30 Battelle Memorial Institute
US4088746A (en) * 1976-11-11 1978-05-09 Bio-Rad Laboratories, Inc. Radioimmunoassay for thyroid-stimulating hormone (TSH)

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2797149A (en) * 1953-01-08 1957-06-25 Technicon International Ltd Methods of and apparatus for analyzing liquids containing crystalloid and non-crystalloid constituents
DE1523058A1 (de) * 1962-09-05 1968-12-12 Technicon Instr Verfahren und Vorrichtung zum Feststellen,welche einer Anzahl von Blutproben mit einem bestimmten Stoff eine Agglutinationsreaktion eingehen
GB1420916A (en) * 1971-09-08 1976-01-14 Bagshawe K D Performance of chemical or biological reactions
US3896217A (en) * 1973-03-19 1975-07-22 Summa Corp Method and apparatus for radioimmunoassay with regeneration of immunoadsorbent
US3925018A (en) * 1973-06-08 1975-12-09 Technicon Instr Method and apparatus for quantitative analysis utilizing particulate reagent material

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0054675A1 (fr) * 1980-12-23 1982-06-30 Roche Diagnostics GmbH Procédé de détermination immunoenzymatique en phase hétérogène
EP0210107A1 (fr) * 1985-07-26 1987-01-28 Lyonnaise Des Eaux - Dumez Procédé de dosage immunologique en continu de composés organiques dans un fluide en circulation, et dispositif de mise en oeuvre
FR2585367A1 (fr) * 1985-07-26 1987-01-30 Lyonnaise Eaux Procede de dosage immunologique en continu de composes organiques dans un fluide en circulation, et dispositif de mise en oeuvre

Also Published As

Publication number Publication date
AT357272B (de) 1980-06-25
ES462365A1 (es) 1978-06-01
IT1087524B (it) 1985-06-04
ATA637377A (de) 1979-11-15
AU2889577A (en) 1979-03-22
US4251360A (en) 1981-02-17
NL7710018A (nl) 1978-03-21
JPS5366418A (en) 1978-06-13
AU513350B2 (en) 1980-11-27

Similar Documents

Publication Publication Date Title
FR2379072A1 (fr) Procede et necessaire de dosage, par chromatographie sur colonne, d'une substance pouvant faire l'objet d'une fixation specifique
FR2447966A1 (fr) Conjugues analogue de ligand-inhibiteur enzymatique irreversible et procedes pour la determination des ligands les utilisant
FR2365124A1 (fr) Procede et appareillage pour la detection d'une proteine de fixation specifique ou d'une substance capable de se livrer sur cette proteine
IT8026882A0 (it) Contenuta in un campione. metodo e dispositivo per determinare in particolare la quantita' di carbonio organico
BR7406253D0 (pt) Processo e aparelho para determinar a concentracao de uma substancia eletroativa numa solucao de amostra de fluxo direto
ES523242A0 (es) "procedimiento de obtencion de un elemento analitico para determinar un analito en una muestra liquida".
DE3575471D1 (de) Behandlungskarte fuer eine zentrifuge.
FR2357896A1 (fr) Procede et appareil d'entretien d'une matiere dans un etat chimique det
BE849183A (fr) Cuve a plusieurs chambres, notamment pour l'analyse automatique d'echantillons biologiques liquides
FR2412067A1 (fr) Dispositif pour suivre les variations de la composition d'un melange liquide heterogene en ecoulement
IT8348715A0 (it) Contenitore per piccole quantita'di liquidi in particolare per analisi di liquidi biologici
BE900588A (fr) Procede pour concentrer le solute lors de l'injection dans une colonne de chromatographie en phase gazeuse.
SE8603428D0 (sv) Analyssystem
BE837122A (fr) Appareil et procede de regulation de l'alimentation en reactif dans l'analyse automatique des liquides
CH527417A (fr) Procédé de préparation d'un plusieurs échantillons sous forme liquide, destinés à l'analyse ou au dosage d'éléments radioactifs
HUT42703A (en) Sample holding device for discrete analysis of liquid materials to be analysed
FR2274038A1 (fr) Methode photometrique pour la determination quantitative d'un corps dans une substance a analyser
BR7703146A (pt) Composicao de materia;processo de preparacao de uma composicao de materia,util para analise quantitativa ou semelhantes;processo para a realizacao de um radio-ensaio aglutinante;e derivados,compostos e isocianatos relativos ao processo
FR2355293A2 (fr) Procede de determination du degre d'insaturation d'un support d'un compose biologiquement actif dans un fluide biologique
OA05813A (fr) Procédé et dispositif de traitement de matière multiphase comprenant une phase solide et une phase liquide ou pâteuse.
BE863043A (fr) Reactif et procede d'analyse de la creatinine dans les liquides biologiques
FR2454097B1 (fr) Composition renfermant l'ion ferrocyanure et ses applications au dosage d'acide urique dans un echantillon liquide
FR2390724A1 (fr) Dispositif perfectionne pour preparer un liquide destine a des mesures dans des appareils d'analyse optiques
FR2432047A1 (fr) Procede d'analyse chimique et dispositif pour le mettre en oeuvre
FR2428256A1 (fr) Procede pour le dosage enzymatique de l'acide ascorbique

Legal Events

Date Code Title Description
ST Notification of lapse