GB1420916A - Performance of chemical or biological reactions - Google Patents

Performance of chemical or biological reactions

Info

Publication number
GB1420916A
GB1420916A GB4197271A GB4197271A GB1420916A GB 1420916 A GB1420916 A GB 1420916A GB 4197271 A GB4197271 A GB 4197271A GB 4197271 A GB4197271 A GB 4197271A GB 1420916 A GB1420916 A GB 1420916A
Authority
GB
Grant status
Application
Patent type
Prior art keywords
pad
pads
digoxin
upper
matrix
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB4197271A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bagshawe K D
Original Assignee
Bagshawe K D
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01TMEASUREMENT OF NUCLEAR OR X-RADIATION
    • G01T7/00Details of radiation-measuring instruments
    • G01T7/02Collecting means for receiving or storing samples to be investigated and possibly directly transporting the samples to the measuring arrangement; particularly for investigating radioactive fluids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing

Abstract

1420916 Analytical filter K D BAGSHAWE 8 Dec 1972 [8 Sept 1971 12 Sept 1972] 41972/71 and 42383/72 Heading B1D [Also in Division Gl] A reaction cell, for use in for example radioimmunoassay, comprises a tubular element 11 having enlarged upper and lower parts 12, 13 and a central region containing a matrix pad 17 lodged on an apertured support 16, the matrix pad comprising a porous absorptive material, for example glass fibre filter material. The pad may contain a predetermined amount of antigen or antibody and a pad of fibrous material may be coated before introduction of the reagent with inert maoromolecular material such as albumin. The cell may contain more than one matrix pad. The cell may be fitted to upper member 14, which has prongs 20 which hold the pads in position when wash liquid is introduced at the upper end of the assembly and to lower member 15, which may contain cellulose wadding or absorbent tissue extending slightly above member 15 to touch the matrix pad through aperture 25 and so aid filtration. In use, for example in the determination of digoxin, preprepared matrix pads containing a mixture of rabbit anti-digoxin serum and donkey anti-rabbit serum are inserted into respective reaction cells. Plasma samples being tested and standard solutions are mixed I-125 labelled digoxin and aliquots of of the mixtures pipetted into respective reaction, cells. The upper tubes 14 are attached, the assemblies incubated, the lower tubes 15 are attached, phosphate albumin buffer is introduced into the upper tubes to wash unreacted I-125-labelled digoxin from the pads and the amount of radioactivity left in the pads is determined.
GB4197271A 1971-09-08 1971-09-08 Performance of chemical or biological reactions Expired GB1420916A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
GB4197271A GB1420916A (en) 1971-09-08 1971-09-08 Performance of chemical or biological reactions
GB4238372 1972-09-12

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
GB4197271A GB1420916A (en) 1971-09-08 1971-09-08 Performance of chemical or biological reactions
IT2891572A IT1006557B (en) 1971-09-08 1972-09-07 particularly useful in tests radioimmunita reaction Cella
CA 151114 CA983358A (en) 1971-09-08 1972-09-07 Performance of chemical or biological reactions
DE19722244080 DE2244080A1 (en) 1971-09-08 1972-09-08 A method and apparatus for performing chemical and / or biological reactions
CH1327172A CH575122A5 (en) 1971-09-08 1972-09-08
FR7231880A FR2158810A6 (en) 1970-05-13 1972-09-08 Reaction tube
JP9086872A JPS595863B2 (en) 1971-09-08 1972-09-08
US3888629A US3888629A (en) 1971-09-08 1972-09-08 Performance of chemical or biological reactions within an absorbent matrix pad

Publications (1)

Publication Number Publication Date
GB1420916A true true GB1420916A (en) 1976-01-14

Family

ID=26264792

Family Applications (1)

Application Number Title Priority Date Filing Date
GB4197271A Expired GB1420916A (en) 1971-09-08 1971-09-08 Performance of chemical or biological reactions

Country Status (1)

Country Link
GB (1) GB1420916A (en)

Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2344020A1 (en) * 1976-03-12 1977-10-07 Univ Virginia Method and automatic immunoassay apparatus
FR2365124A1 (en) * 1976-09-18 1978-04-14 Boehringer Mannheim Gmbh Method and apparatus for detection of a specific binding protein or a substance capable of delivery on this protein
EP0200381A1 (en) * 1985-04-04 1986-11-05 Hybritech Incorporated A solid phase system for use in ligand-receptor assays
EP0249877A2 (en) * 1986-06-20 1987-12-23 Boehringer Mannheim Gmbh Process for the preparation of an immunoreactive support material for heterogeneous immunological analysis
EP0290921A2 (en) * 1987-05-09 1988-11-17 Boehringer Mannheim Gmbh Test-piece for the analysis of a liquid sample and method for its preparation
GB2218200A (en) * 1988-03-31 1989-11-08 Cambridge Biomedical Limited Determining analytes
WO1989010979A1 (en) * 1988-05-10 1989-11-16 E.I. Du Pont De Nemours And Company Process for rapid nucleic acid detection
EP0369361A2 (en) * 1988-11-17 1990-05-23 Becton Dickinson and Company Immunoassay on a preblocked solid surface
EP0379347A2 (en) * 1989-01-17 1990-07-25 Eastman Kodak Company Enzyme-labeled receptor composition, diagnostic kit and use in method to determine a ligand
EP0389003A1 (en) * 1985-10-04 1990-09-26 Abbott Laboratories Solid-phase analytical device and method for using same
EP0395430A2 (en) * 1989-04-28 1990-10-31 Sangstat Medical Corporation Matrix controlled device and method
GB2206964B (en) * 1986-12-04 1991-04-24 David Michael Kemeny Solid phase immunoassay
US5160701A (en) * 1986-02-18 1992-11-03 Abbott Laboratories Solid-phase analytical device and method for using same
US5162238A (en) * 1987-11-28 1992-11-10 Boehringer Mannheim Gmbh Test carrier for analysis of a liquid sample
US5374524A (en) * 1988-05-10 1994-12-20 E. I. Du Pont De Nemours And Company Solution sandwich hybridization, capture and detection of amplified nucleic acids
EP0415983B1 (en) * 1988-05-10 1995-11-22 E.I. Du Pont De Nemours And Company Assay device and immunoassay
WO1996014931A1 (en) * 1994-11-10 1996-05-23 Minnesota Mining And Manufacturing Company Solid phase extraction using composite sheet for direct measurement of radioactivity

Cited By (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2344020A1 (en) * 1976-03-12 1977-10-07 Univ Virginia Method and automatic immunoassay apparatus
FR2365124A1 (en) * 1976-09-18 1978-04-14 Boehringer Mannheim Gmbh Method and apparatus for detection of a specific binding protein or a substance capable of delivery on this protein
EP0200381A1 (en) * 1985-04-04 1986-11-05 Hybritech Incorporated A solid phase system for use in ligand-receptor assays
EP0437287A3 (en) * 1985-04-04 1991-07-24 Hybritech Incorporated A solid phase system for use in ligand-receptor assays
EP0437287A2 (en) * 1985-04-04 1991-07-17 Hybritech Incorporated A solid phase system for use in ligand-receptor assays
EP0389003A1 (en) * 1985-10-04 1990-09-26 Abbott Laboratories Solid-phase analytical device and method for using same
US5008080A (en) * 1985-10-04 1991-04-16 Abbott Laboratories Solid-phase analytical device and method for using same
US5160701A (en) * 1986-02-18 1992-11-03 Abbott Laboratories Solid-phase analytical device and method for using same
EP0249877A2 (en) * 1986-06-20 1987-12-23 Boehringer Mannheim Gmbh Process for the preparation of an immunoreactive support material for heterogeneous immunological analysis
EP0249877A3 (en) * 1986-06-20 1989-02-01 Boehringer Mannheim Gmbh Process for the preparation of an immunoreactive support material for heterogeneous immunological analysis
GB2206964B (en) * 1986-12-04 1991-04-24 David Michael Kemeny Solid phase immunoassay
EP0290921A2 (en) * 1987-05-09 1988-11-17 Boehringer Mannheim Gmbh Test-piece for the analysis of a liquid sample and method for its preparation
EP0290921A3 (en) * 1987-05-09 1990-10-17 Boehringer Mannheim Gmbh Test-piece for the analysis of a liquid sample and method for its preparation
US5162238A (en) * 1987-11-28 1992-11-10 Boehringer Mannheim Gmbh Test carrier for analysis of a liquid sample
GB2218200A (en) * 1988-03-31 1989-11-08 Cambridge Biomedical Limited Determining analytes
GB2218200B (en) * 1988-03-31 1992-01-29 Cambridge Biomedical Limited Test for analytes, using an immobilised binding partner, with washing step; and apparatus therefor.
US5234840A (en) * 1988-03-31 1993-08-10 Porton Cambridge Limited Assay with backwash
US5374524A (en) * 1988-05-10 1994-12-20 E. I. Du Pont De Nemours And Company Solution sandwich hybridization, capture and detection of amplified nucleic acids
WO1989010979A1 (en) * 1988-05-10 1989-11-16 E.I. Du Pont De Nemours And Company Process for rapid nucleic acid detection
EP0415983B1 (en) * 1988-05-10 1995-11-22 E.I. Du Pont De Nemours And Company Assay device and immunoassay
EP0369361A2 (en) * 1988-11-17 1990-05-23 Becton Dickinson and Company Immunoassay on a preblocked solid surface
EP0369361A3 (en) * 1988-11-17 1991-06-05 Becton Dickinson and Company Immunoassay on a preblocked solid surface
EP0379347A3 (en) * 1989-01-17 1992-04-08 Eastman Kodak Company Enzyme-labeled receptor composition, diagnostic kit and use in method to determine a ligand
EP0379347A2 (en) * 1989-01-17 1990-07-25 Eastman Kodak Company Enzyme-labeled receptor composition, diagnostic kit and use in method to determine a ligand
US5135872A (en) * 1989-04-28 1992-08-04 Sangstat Medical Corporation Matrix controlled method of delayed fluid delivery for assays
EP0395430A3 (en) * 1989-04-28 1992-01-29 Sangstat Medical Corporation Matrix controlled device and method
EP0395430A2 (en) * 1989-04-28 1990-10-31 Sangstat Medical Corporation Matrix controlled device and method
WO1996014931A1 (en) * 1994-11-10 1996-05-23 Minnesota Mining And Manufacturing Company Solid phase extraction using composite sheet for direct measurement of radioactivity
US5637506A (en) * 1994-11-10 1997-06-10 Minnesota Mining And Manufacturing Company Solid phase extraction using composite sheet for direct measurement of radioactivity
US5891559A (en) * 1994-11-10 1999-04-06 Minnesota Mining And Manufacturing Co. Solid phase extraction using composite sheet for direct measurement of radioactivity

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Legal Events

Date Code Title Description
PS Patent sealed
PE20 Patent expired after termination of 20 years

Effective date: 19921207