FR2355293A2 - Procede de determination du degre d'insaturation d'un support d'un compose biologiquement actif dans un fluide biologique - Google Patents
Procede de determination du degre d'insaturation d'un support d'un compose biologiquement actif dans un fluide biologiqueInfo
- Publication number
- FR2355293A2 FR2355293A2 FR7718670A FR7718670A FR2355293A2 FR 2355293 A2 FR2355293 A2 FR 2355293A2 FR 7718670 A FR7718670 A FR 7718670A FR 7718670 A FR7718670 A FR 7718670A FR 2355293 A2 FR2355293 A2 FR 2355293A2
- Authority
- FR
- France
- Prior art keywords
- unsaturation
- carrier
- determining
- degree
- active compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
- G01N33/78—Thyroid gland hormones, e.g. T3, T4, TBH, TBG or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
- G01N33/545—Synthetic resin
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/82—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving vitamins or their receptors
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/807—Apparatus included in process claim, e.g. physical support structures
- Y10S436/808—Automated or kit
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/807—Apparatus included in process claim, e.g. physical support structures
- Y10S436/81—Tube, bottle, or dipstick
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Endocrinology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
L'invention concerne un procédé de détermination du degré d'insaturation d'un support d'un composé biologiquement actif dans un fluide biologique, pour mesurer par exemple la capacité de fixation insaturée d'une globuline et d'autres protéines fixant des hormones, en incubant une quantité de substance biologique radioactivement marquée ajoutée à un échantillon du fluide biologique tamponné dans un tube à essai en plastique sur la paroi duquel on a appliqué du glutaraldéhyde avec une protéine spécifique de la substance biologique, accouplée de façon covalente, puis en mesurant la quantité de substance biologique marquée fixée par la protéine spécifique sur la paroi du tube, ou la quantité de substance biologique marquée restée dans le liquide séparé.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/696,959 US4225784A (en) | 1976-06-17 | 1976-06-17 | Covalently bound biological substances to plastic materials and use in radioassay |
Publications (1)
Publication Number | Publication Date |
---|---|
FR2355293A2 true FR2355293A2 (fr) | 1978-01-13 |
Family
ID=24799205
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7718670A Pending FR2355293A2 (fr) | 1976-06-17 | 1977-06-17 | Procede de determination du degre d'insaturation d'un support d'un compose biologiquement actif dans un fluide biologique |
Country Status (4)
Country | Link |
---|---|
US (1) | US4225784A (fr) |
JP (1) | JPS52156696A (fr) |
DE (1) | DE2727206A1 (fr) |
FR (1) | FR2355293A2 (fr) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2436396A1 (fr) * | 1978-09-12 | 1980-04-11 | Baxter Travenol Lab | Procede d'analyse pour determiner directement la concentration d'un composant libre dans un echantillon |
EP0171871A1 (fr) * | 1984-05-29 | 1986-02-19 | Warner-Lambert Company | Procédé pour déterminer la capacité de fixation insaturée d'une protéine de sérum |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4451571A (en) * | 1981-04-06 | 1984-05-29 | University Patents, Inc. | Preparation of samples for vitamin B12 and/or folate assay and assay |
US4604348A (en) * | 1981-11-19 | 1986-08-05 | New York Blood Center, Inc. | Composition for use in immunoassays |
US4477578A (en) * | 1982-03-04 | 1984-10-16 | Medical & Scientific, Inc. | Method and apparatus for performing assays |
US6936694B1 (en) * | 1982-05-06 | 2005-08-30 | Intermune, Inc. | Manufacture and expression of large structural genes |
US4652639A (en) * | 1982-05-06 | 1987-03-24 | Amgen | Manufacture and expression of structural genes |
DE3311889A1 (de) * | 1983-03-31 | 1984-10-11 | Byk-Mallinckrodt Chemische Produkte Gmbh, 6057 Dietzenbach | Verfahren zur irreversiblen bindung von protein an polystyroloberflaechen unter erhaltung der biologischen aktivitaet, so erhaltene polystyroloberflaechen und ihre verwendung |
US4623629A (en) | 1983-10-31 | 1986-11-18 | Daniel Kerschensteiner | Solid-phase immunoassay support and method of use thereof |
US6326136B1 (en) | 1988-04-01 | 2001-12-04 | Digene Corporation | Macromolecular conjugate made using unsaturated aldehydes |
US5053054A (en) * | 1988-09-12 | 1991-10-01 | Ortho Pharmaceutical Corporation | Methods and reagents for staining intracellular components |
US5354692A (en) * | 1992-09-08 | 1994-10-11 | Pacific Biotech, Inc. | Analyte detection device including a hydrophobic barrier for improved fluid flow |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3414383A (en) * | 1965-08-09 | 1968-12-03 | Canadian Patents Dev | Determination of thyroxine |
SE326845B (fr) * | 1966-10-21 | 1970-08-03 | Pharmacia Ab | |
SE337223B (fr) * | 1967-05-23 | 1971-08-02 | Pharmacia Ab | |
CH564031A5 (fr) * | 1968-03-29 | 1975-07-15 | Anvar | |
US3646346A (en) * | 1968-12-26 | 1972-02-29 | Pharmacia Ab | Antibody-coated tube system for radioimmunoassay |
US3666854A (en) * | 1969-07-30 | 1972-05-30 | Nuclear Med Lab | Test for thyroid hormone |
GB1392181A (en) * | 1971-04-16 | 1975-04-30 | Rech Et Dapplications Soc Gen | Fixation of nitrogenous materials |
US3826619A (en) * | 1971-12-21 | 1974-07-30 | Abbott Lab | Test apparatus for direct radioimmuno-assay for antigens and their antibodies |
US3941876A (en) * | 1973-04-25 | 1976-03-02 | Gte New Ventures Corporation | In vitro method for determining allergic hypersensitivity |
US3949064A (en) * | 1973-10-26 | 1976-04-06 | Baxter Laboratories, Inc. | Method of detecting antigens or antibodies |
US3951748A (en) * | 1974-11-11 | 1976-04-20 | Medical Products, Inc. | Sensitized matrix for detection of disease |
-
1976
- 1976-06-17 US US05/696,959 patent/US4225784A/en not_active Expired - Lifetime
-
1977
- 1977-06-16 DE DE19772727206 patent/DE2727206A1/de not_active Withdrawn
- 1977-06-16 JP JP7198977A patent/JPS52156696A/ja active Pending
- 1977-06-17 FR FR7718670A patent/FR2355293A2/fr active Pending
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2436396A1 (fr) * | 1978-09-12 | 1980-04-11 | Baxter Travenol Lab | Procede d'analyse pour determiner directement la concentration d'un composant libre dans un echantillon |
EP0171871A1 (fr) * | 1984-05-29 | 1986-02-19 | Warner-Lambert Company | Procédé pour déterminer la capacité de fixation insaturée d'une protéine de sérum |
Also Published As
Publication number | Publication date |
---|---|
US4225784A (en) | 1980-09-30 |
DE2727206A1 (de) | 1977-12-29 |
JPS52156696A (en) | 1977-12-27 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
FR2355293A2 (fr) | Procede de determination du degre d'insaturation d'un support d'un compose biologiquement actif dans un fluide biologique | |
FR2373063A1 (fr) | Procede de dosage avec fixation specifique, en utilisant un modulateur d'enzyme comme substance de marquage | |
DE3705686C2 (de) | Verfahren zur Bestimmung von Antikörpern | |
FR2458072A1 (fr) | Procede, equipement et composition pour l'analyse qualitative et le dosage immuno-enzymatique de substances biologiques | |
LV10538A (lv) | Imunologiski saistamas vielas noteiksanas panemiens biologiska skidruma un diagnostikas lidzeklis | |
FR2447966A1 (fr) | Conjugues analogue de ligand-inhibiteur enzymatique irreversible et procedes pour la determination des ligands les utilisant | |
ES2034245T3 (es) | Determinacion de concentraciones ambiente de varios analitos. | |
FR2415301A1 (fr) | Procede et composition pour determination par fixation specifique avec un recepteur double d'un ligand echantillon | |
FR2436396A1 (fr) | Procede d'analyse pour determiner directement la concentration d'un composant libre dans un echantillon | |
FR2366568A1 (fr) | Procede pour la determination d'une substance immunologiquement active | |
BE849183A (fr) | Cuve a plusieurs chambres, notamment pour l'analyse automatique d'echantillons biologiques liquides | |
FR2449895A1 (fr) | Determination d'iso-enzymes de creatine kinase au moyen de complexes anticorps-isoenzyme immobilises | |
FR2445527A1 (fr) | Procede et reactifs pour la determination de l'hemoglobine glucosylee dans le sang | |
GB1524372A (en) | Radioassay of oestrogens | |
ES481208A1 (es) | Un metodo para detectar anticuerpos. | |
KR890702039A (ko) | 1,25-디하이드록시 비타민 d의 분석 방법 | |
FR2396976A1 (fr) | Methode de dosage de cortisol sans extraction | |
FR2396975A1 (fr) | Procede de dosage d'hormones ou de produits pharmaceutiques non lies | |
FR2373795A1 (fr) | Dosage immunologique par enzyme fixee | |
NO943759L (no) | Fremgangsmåte for bestemmelse av mengden av en ligand i et biologisk fluid, samt et analysesett for utförelse av en slik fremgangsmåte | |
Gitlin | SOME CONCEPTS OF PLASMA PROTEIN METABOLISM, AD 1956: E. Mead Johnson Award Address | |
FR2365800A1 (fr) | Procede de determination d'un reactif d'une reaction immunologique | |
FR2378281A1 (fr) | Reactif et procede d'analyse de la creatinine dans les liquides biologiques | |
BE903810A (fr) | Procede de diagnostic pour l'evaluation de parametres cliniques, et dispositif pour sa mise en oeuvre. | |
ATE146596T1 (de) | Diagnostisches verfahren und reagenz für hiv |