FR2357563A1 - Nouvelles 7h-pyrrolo(3,2-f) quinazoline-1,3-diamines substituees en position 7, leur procede de preparation et medicament les contenant - Google Patents
Nouvelles 7h-pyrrolo(3,2-f) quinazoline-1,3-diamines substituees en position 7, leur procede de preparation et medicament les contenantInfo
- Publication number
- FR2357563A1 FR2357563A1 FR7721232A FR7721232A FR2357563A1 FR 2357563 A1 FR2357563 A1 FR 2357563A1 FR 7721232 A FR7721232 A FR 7721232A FR 7721232 A FR7721232 A FR 7721232A FR 2357563 A1 FR2357563 A1 FR 2357563A1
- Authority
- FR
- France
- Prior art keywords
- quinazoline
- pyrrolo
- preparation
- new
- product containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229940126601 medicinal product Drugs 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 229910052783 alkali metal Inorganic materials 0.000 abstract 2
- AMQWKZUAOLLUPP-UHFFFAOYSA-N 7h-pyrrolo[3,2-f]quinazoline-1,3-diamine Chemical class C1=CC2=NC(N)=NC(N)=C2C2=C1NC=C2 AMQWKZUAOLLUPP-UHFFFAOYSA-N 0.000 abstract 1
- 241000894006 Bacteria Species 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- -1 alkali metal salt Chemical class 0.000 abstract 1
- 150000001340 alkali metals Chemical class 0.000 abstract 1
- 239000002585 base Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
- C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Nutrition Science (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US70400176A | 1976-07-09 | 1976-07-09 | |
| US70400276A | 1976-07-09 | 1976-07-09 | |
| GB5382176 | 1976-12-23 | ||
| US78498777A | 1977-04-06 | 1977-04-06 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2357563A1 true FR2357563A1 (fr) | 1978-02-03 |
| FR2357563B1 FR2357563B1 (enrdf_load_stackoverflow) | 1983-03-11 |
Family
ID=27449036
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7721232A Granted FR2357563A1 (fr) | 1976-07-09 | 1977-07-08 | Nouvelles 7h-pyrrolo(3,2-f) quinazoline-1,3-diamines substituees en position 7, leur procede de preparation et medicament les contenant |
Country Status (13)
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0639075A4 (en) * | 1990-11-14 | 1993-09-29 | Chiron Corp | SPECIFIC INHIBITION OF DIHYDROFOLATE REDUCTASE AND COMPOUNDS PROVIDED THEREFOR. |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100810468B1 (ko) * | 2001-10-10 | 2008-03-07 | 씨제이제일제당 (주) | 사이클로옥시게나제-2의 저해제로서 선택성이 뛰어난1ｈ-인돌 유도체 |
| US7262297B2 (en) * | 2003-05-15 | 2007-08-28 | Hoffmann-La Roche Inc. | Diaminopyrroloquinazolines compounds as protein tyrosine phosphatase inhibitors |
| US11077109B2 (en) * | 2017-08-01 | 2021-08-03 | The Trustees Of Princeton University | Compounds having antibacterial activity and methods of use |
| JP2023535527A (ja) * | 2020-07-02 | 2023-08-17 | ザ トラスティーズ オブ プリンストン ユニバーシティ | 抗菌活性を有する化合物 |
-
1977
- 1977-06-29 IE IE1345/77A patent/IE45427B1/en unknown
- 1977-07-01 AU AU26687/77A patent/AU507828B2/en not_active Expired
- 1977-07-04 CA CA281,981A patent/CA1093555A/en not_active Expired
- 1977-07-07 PH PH19967A patent/PH13539A/en unknown
- 1977-07-08 NL NL7707658A patent/NL7707658A/xx not_active Application Discontinuation
- 1977-07-08 CH CH850677A patent/CH634069A5/de not_active IP Right Cessation
- 1977-07-08 DK DK309977A patent/DK309977A/da not_active Application Discontinuation
- 1977-07-08 DE DE19772731039 patent/DE2731039A1/de not_active Withdrawn
- 1977-07-08 BE BE179213A patent/BE856647A/xx not_active IP Right Cessation
- 1977-07-08 MX MX775882U patent/MX5133E/es unknown
- 1977-07-08 FR FR7721232A patent/FR2357563A1/fr active Granted
- 1977-07-09 JP JP8247077A patent/JPS539796A/ja active Granted
- 1977-11-15 IN IN1610/CAL/77A patent/IN147488B/en unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0639075A4 (en) * | 1990-11-14 | 1993-09-29 | Chiron Corp | SPECIFIC INHIBITION OF DIHYDROFOLATE REDUCTASE AND COMPOUNDS PROVIDED THEREFOR. |
Also Published As
| Publication number | Publication date |
|---|---|
| DE2731039A1 (de) | 1978-01-19 |
| IE45427B1 (en) | 1982-08-25 |
| JPS6254111B2 (enrdf_load_stackoverflow) | 1987-11-13 |
| CA1093555A (en) | 1981-01-13 |
| AU507828B2 (en) | 1980-02-28 |
| PH13539A (en) | 1980-06-26 |
| BE856647A (fr) | 1978-01-09 |
| FR2357563B1 (enrdf_load_stackoverflow) | 1983-03-11 |
| AU2668777A (en) | 1979-01-04 |
| DK309977A (da) | 1978-01-10 |
| NL7707658A (nl) | 1978-01-11 |
| MX5133E (es) | 1983-03-28 |
| JPS539796A (en) | 1978-01-28 |
| IN147488B (enrdf_load_stackoverflow) | 1980-03-15 |
| IE45427L (en) | 1978-10-06 |
| CH634069A5 (en) | 1983-01-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |