FR2353543B1 - Analogues de 5,6-dihydro-prostacycline et leur preparation - Google Patents

Analogues de 5,6-dihydro-prostacycline et leur preparation

Info

Publication number
FR2353543B1
FR2353543B1 FR7716615A FR7716615A FR2353543B1 FR 2353543 B1 FR2353543 B1 FR 2353543B1 FR 7716615 A FR7716615 A FR 7716615A FR 7716615 A FR7716615 A FR 7716615A FR 2353543 B1 FR2353543 B1 FR 2353543B1
Authority
FR
France
Prior art keywords
dihydro
preparation
prostacycline analogs
prostacycline
analogs
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7716615A
Other languages
English (en)
Other versions
FR2353543A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of FR2353543A1 publication Critical patent/FR2353543A1/fr
Application granted granted Critical
Publication of FR2353543B1 publication Critical patent/FR2353543B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0041—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F3/00—Compounds containing elements of Groups 2 or 12 of the Periodic Table
    • C07F3/10—Mercury compounds

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FR7716615A 1976-06-01 1977-05-31 Analogues de 5,6-dihydro-prostacycline et leur preparation Expired FR2353543B1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US69140076A 1976-06-01 1976-06-01
US69139976A 1976-06-01 1976-06-01
US78814677A 1977-04-19 1977-04-19
US78814777A 1977-04-19 1977-04-19

Publications (2)

Publication Number Publication Date
FR2353543A1 FR2353543A1 (fr) 1977-12-30
FR2353543B1 true FR2353543B1 (fr) 1986-02-21

Family

ID=27505431

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7716615A Expired FR2353543B1 (fr) 1976-06-01 1977-05-31 Analogues de 5,6-dihydro-prostacycline et leur preparation

Country Status (13)

Country Link
JP (1) JPS5936912B2 (fr)
AU (1) AU508891B2 (fr)
BE (1) BE855224A (fr)
CA (1) CA1196632A (fr)
CH (1) CH640847A5 (fr)
DE (1) DE2724555A1 (fr)
FR (1) FR2353543B1 (fr)
GB (1) GB1554048A (fr)
IE (1) IE45604B1 (fr)
IL (1) IL52099A (fr)
MX (1) MX4813E (fr)
NL (1) NL7705991A (fr)
SE (3) SE436744B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL51189A (en) * 1976-02-04 1985-08-30 Upjohn Co Prostaglandin analogs
FI71138C (fi) 1976-12-31 1986-11-24 Erba Farmitalia Foerfarande foer framstaellning av terapeutiskt aktiva bisykliska prostaglandiner
AU524786B2 (en) * 1977-03-07 1982-10-07 The Upjohn Company Prostacyclins
DE2743283A1 (de) * 1977-09-27 1979-04-05 Hoechst Ag Neue prostacyclin-analoga
DE2811950A1 (de) * 1978-03-18 1979-12-13 Hoechst Ag Neue analoga von prostacyclin
US4237060A (en) 1979-03-23 1980-12-02 Hoffmann-La Roche Inc. Prostacyclin analogs
CA2382759A1 (fr) 1999-08-05 2001-02-15 Teijin Limited Ameliorant contre la neuropathie contenant des composes azotes en tant que principe actif

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1079025B (it) * 1976-05-11 1985-05-08 Wellcome Found Perfezionamento nella preparazione di eteri

Also Published As

Publication number Publication date
AU508891B2 (en) 1980-04-03
IL52099A (en) 1985-03-31
DE2724555A1 (de) 1977-12-15
IE45604L (en) 1977-12-01
NL7705991A (nl) 1977-12-05
IL52099A0 (en) 1977-07-31
SE7706245L (sv) 1977-12-16
BE855224A (fr) 1977-11-30
GB1554048A (en) 1979-10-17
CA1196632A (fr) 1985-11-12
AU2508677A (en) 1978-11-16
MX4813E (es) 1982-10-19
JPS52156854A (en) 1977-12-27
SE8201649L (sv) 1982-03-16
FR2353543A1 (fr) 1977-12-30
SE436744B (sv) 1985-01-21
SE7811142L (sv) 1978-11-28
SE432101B (sv) 1984-03-19
CH640847A5 (en) 1984-01-31
JPS5936912B2 (ja) 1984-09-06
IE45604B1 (en) 1982-10-06

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Legal Events

Date Code Title Description
ST Notification of lapse