FR2328473A1 - Nouveaux derives de la cephalosporine utiles comme antibiotiques et leurs procedes de preparation - Google Patents

Nouveaux derives de la cephalosporine utiles comme antibiotiques et leurs procedes de preparation

Info

Publication number
FR2328473A1
FR2328473A1 FR7631922A FR7631922A FR2328473A1 FR 2328473 A1 FR2328473 A1 FR 2328473A1 FR 7631922 A FR7631922 A FR 7631922A FR 7631922 A FR7631922 A FR 7631922A FR 2328473 A1 FR2328473 A1 FR 2328473A1
Authority
FR
France
Prior art keywords
antibiotics
preparation methods
derivatives useful
cephalosporin derivatives
new cephalosporin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7631922A
Other languages
English (en)
Other versions
FR2328473B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yeda Research and Development Co Ltd
Original Assignee
Yeda Research and Development Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yeda Research and Development Co Ltd filed Critical Yeda Research and Development Co Ltd
Publication of FR2328473A1 publication Critical patent/FR2328473A1/fr
Application granted granted Critical
Publication of FR2328473B1 publication Critical patent/FR2328473B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00—Compounds containing azido groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/64—Acyl halides
    • C07C57/76—Acyl halides containing halogen outside the carbonyl halide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Saccharide Compounds (AREA)
FR7631922A 1975-10-24 1976-10-22 Nouveaux derives de la cephalosporine utiles comme antibiotiques et leurs procedes de preparation Granted FR2328473A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/625,558 US4045438A (en) 1975-10-24 1975-10-24 Cephalosporin antibiotics

Publications (2)

Publication Number Publication Date
FR2328473A1 true FR2328473A1 (fr) 1977-05-20
FR2328473B1 FR2328473B1 (fr) 1980-04-18

Family

ID=24506643

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7631922A Granted FR2328473A1 (fr) 1975-10-24 1976-10-22 Nouveaux derives de la cephalosporine utiles comme antibiotiques et leurs procedes de preparation

Country Status (16)

Country Link
US (2) US4045438A (fr)
JP (1) JPS5253891A (fr)
AU (1) AU503552B2 (fr)
BE (1) BE847550A (fr)
CA (1) CA1074783A (fr)
DE (1) DE2647515A1 (fr)
DK (1) DK479976A (fr)
ES (1) ES452638A1 (fr)
FR (1) FR2328473A1 (fr)
GB (1) GB1509500A (fr)
IE (1) IE43874B1 (fr)
NL (1) NL7611706A (fr)
NO (1) NO763601L (fr)
NZ (1) NZ182399A (fr)
SE (1) SE7611778L (fr)
ZA (1) ZA766306B (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1527109A (en) * 1974-12-28 1978-10-04 Asahi Chemical Ind Cephalosporin derivatives and process for preparing same
US4200744A (en) * 1976-01-22 1980-04-29 Toyama Chemical Company, Limited Substituted 7α-methoxy-7β[(2,3-dioxo-1-piperazinyl)carbonylaminophenylacetamido]cephalosporins
AU498968B2 (en) * 1976-03-03 1979-03-29 Sumitomo Chemical Company, Limited Cephalosporins
US4144248A (en) * 1976-03-04 1979-03-13 Sagami Chemical Research Center Aromatic acetic acid derivatives having sulfur atom at alpha-position and process for their preparation
US4180571A (en) * 1976-03-25 1979-12-25 Shionogi & Co., Ltd. Arylmalonamido-1-oxadethiacephalosporins
US4148817A (en) * 1976-03-25 1979-04-10 Eli Lilly And Company Process and intermediates for preparing cephalosporin antibiotics
CA1100962A (fr) * 1977-04-28 1981-05-12 Yoshio Hamashima Haloarylmalonamidooxacephalosporines
US4117123A (en) * 1977-06-09 1978-09-26 Smithkline Corporation 7-Acylamino-3-[1-(2-sulfamidoethyl)tetrazol-5-ylthiomethyl]-3-cephem-4-carboxylic acids
US4117125A (en) * 1977-06-24 1978-09-26 Smithkline Corporation 7-Acylamino-3-[1-[2-(carboxymethylamino]ethyl) tetrazol-5-ylthiomethyl]-3-cephem-4-carboxylic acids
US4117124A (en) * 1977-06-30 1978-09-26 Smithkline Corporation 7-Acylamino-3-[[3-(carboxymethyl)thio-1H-1,2,4-triazol-5-yl]thiomethyl]-3-cephem-4-carboxylic acids
JPS609718B2 (ja) * 1977-08-25 1985-03-12 塩野義製薬株式会社 チアジアゾリルチオセフアロスポリン類縁抗生物質
US4118563A (en) * 1977-11-25 1978-10-03 Bristol-Myers Company Production of 7-(2-aminomethylphenylacetamido-3-(1-carboxymethyltetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid
US4236002A (en) * 1977-12-23 1980-11-25 Yeda Research & Development Co., Ltd. Cephalosporin derivatives
US4263292A (en) * 1978-06-13 1981-04-21 Toyama Chemical Co., Ltd. 7α-methoxycephalosporins and pharmaceutical composition comprising the same
JPS5690088A (en) * 1979-11-02 1981-07-21 Meiji Seika Kaisha Ltd Novel cephalosporin analog compound
GB9520355D0 (en) * 1995-10-05 1995-12-06 Zeneca Ltd Chemical process
AU2014218598B2 (en) 2013-02-25 2016-08-04 The Board Of Regents Of The University Of Texas System Neoseptins: small molecule adjuvants

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA892580A (en) 1972-02-08 Patchornik Avraham Polymer acylation of penicillins
US3341531A (en) * 1967-02-15 1967-09-12 American Cyanamid Co Substituted 7-acetylamino cephalosporanic acids
GB1229453A (fr) 1968-01-30 1971-04-21
US3657232A (en) 1970-06-19 1972-04-18 R & L Molecular Research Ltd 7-((o-aminomethylphenylthio)-acetamido) cephalosporanic acid
US3855213A (en) * 1971-02-18 1974-12-17 Smith Kline French Lab 3-heterocyclic thiomethyl-cephalosporins
DE2118635A1 (de) * 1971-04-17 1972-11-02 Farbwerke Hoechst AG, vormals Meister Lucius & Brüning, 6000 Frankfurt Acylaminocephalosporansäuren und Verfahren zu ihrer Herstellung
US3812116A (en) * 1971-07-02 1974-05-21 Fujisawa Pharmaceutical Co 7-acylated 3-substituted cephalosporin compounds
US3778432A (en) 1971-12-13 1973-12-11 Merck & Co Inc Isocyanates and carbamates of penicillins and 3-cephem-4-carboxylic acids
NL7305936A (fr) * 1972-05-05 1973-11-07
US3919206A (en) * 1973-09-25 1975-11-11 Yeda Res & Dev 7-(Halomethylaryl)acetamidocephalosporin derivatives
US3919208A (en) * 1973-10-09 1975-11-11 Yeda Res & Dev 7-(Cyanomethylaryl)acetamide-cephalosporin derivatives
US4026887A (en) * 1975-10-24 1977-05-31 Yeda Research & Development Co. Ltd. Cephalosporin antibiotics

Also Published As

Publication number Publication date
FR2328473B1 (fr) 1980-04-18
ZA766306B (en) 1977-09-28
US4045438A (en) 1977-08-30
NZ182399A (en) 1978-06-02
DE2647515A1 (de) 1977-05-05
NL7611706A (nl) 1977-04-26
IE43874B1 (en) 1981-06-17
GB1509500A (en) 1978-05-04
AU503552B2 (en) 1979-09-06
JPS5253891A (en) 1977-04-30
NO763601L (fr) 1977-04-26
CA1074783A (fr) 1980-04-01
DK479976A (da) 1977-04-25
SE7611778L (sv) 1977-04-25
BE847550A (fr) 1977-02-14
IE43874L (en) 1977-04-24
US4118562A (en) 1978-10-03
ES452638A1 (es) 1977-10-01
AU1891876A (en) 1978-04-27

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Legal Events

Date Code Title Description
ST Notification of lapse