ES452638A1 - Procedimiento para la preparacion de nuevos compuestos deri-vados antibioticos de cefalosporina. - Google Patents

Procedimiento para la preparacion de nuevos compuestos deri-vados antibioticos de cefalosporina.

Info

Publication number
ES452638A1
ES452638A1 ES452638A ES452638A ES452638A1 ES 452638 A1 ES452638 A1 ES 452638A1 ES 452638 A ES452638 A ES 452638A ES 452638 A ES452638 A ES 452638A ES 452638 A1 ES452638 A1 ES 452638A1
Authority
ES
Spain
Prior art keywords
cephalosporin antibiotics
cephalosporin
antibiotics
cephalosporin antibiotic
antibiotic derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES452638A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yeda Research and Development Co Ltd
Original Assignee
Yeda Research and Development Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yeda Research and Development Co Ltd filed Critical Yeda Research and Development Co Ltd
Publication of ES452638A1 publication Critical patent/ES452638A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00Compounds containing azido groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • C07C57/58Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/64Acyl halides
    • C07C57/76Acyl halides containing halogen outside the carbonyl halide groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Saccharide Compounds (AREA)
ES452638A 1975-10-24 1976-10-22 Procedimiento para la preparacion de nuevos compuestos deri-vados antibioticos de cefalosporina. Expired ES452638A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/625,558 US4045438A (en) 1975-10-24 1975-10-24 Cephalosporin antibiotics

Publications (1)

Publication Number Publication Date
ES452638A1 true ES452638A1 (es) 1977-10-01

Family

ID=24506643

Family Applications (1)

Application Number Title Priority Date Filing Date
ES452638A Expired ES452638A1 (es) 1975-10-24 1976-10-22 Procedimiento para la preparacion de nuevos compuestos deri-vados antibioticos de cefalosporina.

Country Status (16)

Country Link
US (2) US4045438A (es)
JP (1) JPS5253891A (es)
AU (1) AU503552B2 (es)
BE (1) BE847550A (es)
CA (1) CA1074783A (es)
DE (1) DE2647515A1 (es)
DK (1) DK479976A (es)
ES (1) ES452638A1 (es)
FR (1) FR2328473A1 (es)
GB (1) GB1509500A (es)
IE (1) IE43874B1 (es)
NL (1) NL7611706A (es)
NO (1) NO763601L (es)
NZ (1) NZ182399A (es)
SE (1) SE7611778L (es)
ZA (1) ZA766306B (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1527109A (en) * 1974-12-28 1978-10-04 Asahi Chemical Ind Cephalosporin derivatives and process for preparing same
US4200744A (en) * 1976-01-22 1980-04-29 Toyama Chemical Company, Limited Substituted 7α-methoxy-7β[(2,3-dioxo-1-piperazinyl)carbonylaminophenylacetamido]cephalosporins
AU498968B2 (en) * 1976-03-03 1979-03-29 Sumitomo Chemical Company, Limited Cephalosporins
US4144248A (en) * 1976-03-04 1979-03-13 Sagami Chemical Research Center Aromatic acetic acid derivatives having sulfur atom at alpha-position and process for their preparation
US4148817A (en) * 1976-03-25 1979-04-10 Eli Lilly And Company Process and intermediates for preparing cephalosporin antibiotics
US4180571A (en) * 1976-03-25 1979-12-25 Shionogi & Co., Ltd. Arylmalonamido-1-oxadethiacephalosporins
CA1100962A (en) * 1977-04-28 1981-05-12 Yoshio Hamashima Haloarylmalonamidooxacephalosporins
US4117123A (en) * 1977-06-09 1978-09-26 Smithkline Corporation 7-Acylamino-3-[1-(2-sulfamidoethyl)tetrazol-5-ylthiomethyl]-3-cephem-4-carboxylic acids
US4117125A (en) * 1977-06-24 1978-09-26 Smithkline Corporation 7-Acylamino-3-[1-[2-(carboxymethylamino]ethyl) tetrazol-5-ylthiomethyl]-3-cephem-4-carboxylic acids
US4117124A (en) * 1977-06-30 1978-09-26 Smithkline Corporation 7-Acylamino-3-[[3-(carboxymethyl)thio-1H-1,2,4-triazol-5-yl]thiomethyl]-3-cephem-4-carboxylic acids
JPS609718B2 (ja) * 1977-08-25 1985-03-12 塩野義製薬株式会社 チアジアゾリルチオセフアロスポリン類縁抗生物質
US4118563A (en) * 1977-11-25 1978-10-03 Bristol-Myers Company Production of 7-(2-aminomethylphenylacetamido-3-(1-carboxymethyltetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid
US4236002A (en) * 1977-12-23 1980-11-25 Yeda Research & Development Co., Ltd. Cephalosporin derivatives
US4263292A (en) * 1978-06-13 1981-04-21 Toyama Chemical Co., Ltd. 7α-methoxycephalosporins and pharmaceutical composition comprising the same
JPS5690088A (en) * 1979-11-02 1981-07-21 Meiji Seika Kaisha Ltd Novel cephalosporin analog compound
GB9520355D0 (en) * 1995-10-05 1995-12-06 Zeneca Ltd Chemical process
CN105339346B (zh) 2013-02-25 2017-03-08 斯克里普斯研究学院 Neoseptin:小分子佐剂

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA892580A (en) 1972-02-08 Patchornik Avraham Polymer acylation of penicillins
US3341531A (en) * 1967-02-15 1967-09-12 American Cyanamid Co Substituted 7-acetylamino cephalosporanic acids
GB1229453A (es) 1968-01-30 1971-04-21
US3657232A (en) 1970-06-19 1972-04-18 R & L Molecular Research Ltd 7-((o-aminomethylphenylthio)-acetamido) cephalosporanic acid
US3855213A (en) * 1971-02-18 1974-12-17 Smith Kline French Lab 3-heterocyclic thiomethyl-cephalosporins
DE2118635A1 (de) * 1971-04-17 1972-11-02 Farbwerke Hoechst AG, vormals Meister Lucius & Brüning, 6000 Frankfurt Acylaminocephalosporansäuren und Verfahren zu ihrer Herstellung
US3812116A (en) * 1971-07-02 1974-05-21 Fujisawa Pharmaceutical Co 7-acylated 3-substituted cephalosporin compounds
US3778432A (en) 1971-12-13 1973-12-11 Merck & Co Inc Isocyanates and carbamates of penicillins and 3-cephem-4-carboxylic acids
NL7305936A (es) * 1972-05-05 1973-11-07
US3919206A (en) * 1973-09-25 1975-11-11 Yeda Res & Dev 7-(Halomethylaryl)acetamidocephalosporin derivatives
US3919208A (en) * 1973-10-09 1975-11-11 Yeda Res & Dev 7-(Cyanomethylaryl)acetamide-cephalosporin derivatives
US4026887A (en) * 1975-10-24 1977-05-31 Yeda Research & Development Co. Ltd. Cephalosporin antibiotics

Also Published As

Publication number Publication date
IE43874B1 (en) 1981-06-17
DK479976A (da) 1977-04-25
US4045438A (en) 1977-08-30
SE7611778L (sv) 1977-04-25
GB1509500A (en) 1978-05-04
AU1891876A (en) 1978-04-27
IE43874L (en) 1977-04-24
BE847550A (fr) 1977-02-14
AU503552B2 (en) 1979-09-06
ZA766306B (en) 1977-09-28
FR2328473B1 (es) 1980-04-18
DE2647515A1 (de) 1977-05-05
NZ182399A (en) 1978-06-02
FR2328473A1 (fr) 1977-05-20
JPS5253891A (en) 1977-04-30
NO763601L (es) 1977-04-26
NL7611706A (nl) 1977-04-26
CA1074783A (en) 1980-04-01
US4118562A (en) 1978-10-03

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