FR2303552A1 - Antitumour naphthacene deriv - prepd. by redn. of carminomycin or culture of Streptomyces microorganisms - Google Patents

Antitumour naphthacene deriv - prepd. by redn. of carminomycin or culture of Streptomyces microorganisms

Info

Publication number
FR2303552A1
FR2303552A1 FR7507893A FR7507893A FR2303552A1 FR 2303552 A1 FR2303552 A1 FR 2303552A1 FR 7507893 A FR7507893 A FR 7507893A FR 7507893 A FR7507893 A FR 7507893A FR 2303552 A1 FR2303552 A1 FR 2303552A1
Authority
FR
France
Prior art keywords
redn
deriv
carminomycin
naphthacene
prepd
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7507893A
Other languages
French (fr)
Other versions
FR2303552B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc Industries SA
Original Assignee
Rhone Poulenc Industries SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Industries SA filed Critical Rhone Poulenc Industries SA
Priority to FR7507893A priority Critical patent/FR2303552A1/en
Priority to NL7602342A priority patent/NL7602342A/en
Priority to AU11900/76A priority patent/AU1190076A/en
Priority to IL49197A priority patent/IL49197A0/en
Priority to DK110176A priority patent/DK110176A/en
Priority to NO760873A priority patent/NO760873L/no
Priority to JP51027038A priority patent/JPS51115992A/en
Priority to CH310676A priority patent/CH615222A5/en
Priority to GB10045/76A priority patent/GB1510571A/en
Priority to CA248,335A priority patent/CA1068225A/en
Priority to HU76RO883A priority patent/HU175158B/en
Priority to NZ180300A priority patent/NZ180300A/en
Priority to AT185876A priority patent/AT342767B/en
Priority to FI760645A priority patent/FI760645A/fi
Priority to LU74541A priority patent/LU74541A1/xx
Priority to ES446006A priority patent/ES446006A1/en
Priority to BE165145A priority patent/BE839540A/en
Priority to ZA761526A priority patent/ZA761526B/en
Priority to DE19762610557 priority patent/DE2610557A1/en
Publication of FR2303552A1 publication Critical patent/FR2303552A1/en
Priority to FI782167A priority patent/FI782167A/en
Priority to FI782168A priority patent/FI782168A/en
Application granted granted Critical
Publication of FR2303552B1 publication Critical patent/FR2303552B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The naphthacene deriv. of formula (I) and its acid-addn. salts are new: (I) has antitumour activity against solid and ascitic tumours and is esp. useful for the treatment of human carcinoma. (I) can be prepd. e.g. by microbiological redn. of carminomycin with a culture (or cells or enzymatic extracts isolated therefrom) of Strept. lavendulae ATCC 8664, STrept. roseochromogenes ATCC 13400, Corynebact. simplex ATCC 6946 or Bacterium cyclooxydans ATCC 12673.
FR7507893A 1975-03-13 1975-03-13 Antitumour naphthacene deriv - prepd. by redn. of carminomycin or culture of Streptomyces microorganisms Granted FR2303552A1 (en)

Priority Applications (21)

Application Number Priority Date Filing Date Title
FR7507893A FR2303552A1 (en) 1975-03-13 1975-03-13 Antitumour naphthacene deriv - prepd. by redn. of carminomycin or culture of Streptomyces microorganisms
NL7602342A NL7602342A (en) 1975-03-13 1976-03-05 NAFTACEEN DERIVATIVE WITH ANTIBIOTIC ACTIVITY.
IL49197A IL49197A0 (en) 1975-03-13 1976-03-11 An antibiotic designated 32,999 rp,processes for the preparation thereof and pharmaceutical compositions containing the same
AU11900/76A AU1190076A (en) 1975-03-13 1976-03-11 Antibiotic
ES446006A ES446006A1 (en) 1975-03-13 1976-03-12 Procedure for the preparation of a new basic antitumor substance, designated by number 32,999 rp. (Machine-translation by Google Translate, not legally binding)
JP51027038A JPS51115992A (en) 1975-03-13 1976-03-12 Novel antibiotic
CH310676A CH615222A5 (en) 1975-03-13 1976-03-12 Process for the preparation of a new naphthacene derivative
GB10045/76A GB1510571A (en) 1975-03-13 1976-03-12 Aminoglycosidic antibiotic
CA248,335A CA1068225A (en) 1975-03-13 1976-03-12 Naphtacene derivatives, their preparation and compounds thereof
HU76RO883A HU175158B (en) 1975-03-13 1976-03-12 Process for producing naphtacene derivatives
DK110176A DK110176A (en) 1975-03-13 1976-03-12 PROCEDURE FOR PREPARING A NAPHTHACENE DERIVATIVE
AT185876A AT342767B (en) 1975-03-13 1976-03-12 METHOD FOR PRODUCING A NEW ANTIBIOTIC
FI760645A FI760645A (en) 1975-03-13 1976-03-12
LU74541A LU74541A1 (en) 1975-03-13 1976-03-12
NO760873A NO760873L (en) 1975-03-13 1976-03-12
BE165145A BE839540A (en) 1975-03-13 1976-03-12 NEW DERIVATIVE OF NAPHTACENE, ITS PREPARATION AND THE COMPOSITIONS CONTAINING IT
ZA761526A ZA761526B (en) 1975-03-13 1976-03-12 New antibiotic
DE19762610557 DE2610557A1 (en) 1975-03-13 1976-03-12 NEW NAPHTHACEN DERIVATIVE, ITS MANUFACTURING AND COMPOSITIONS CONTAINING IT
NZ180300A NZ180300A (en) 1975-03-13 1976-03-12 Antibiotic 32,999 rp produced by microbiological reduction and by cultivation of streptomyces coeruleorubidus(nrrl 3046,nrrl o045nrrl 8098)strepthomyces bifurcus(nrrl3539)andstreptomyces atroviolaceus(nrrl 8148)
FI782167A FI782167A (en) 1975-03-13 1978-07-05 SAETT ATT FRAMSTAELLA ETT DERIVAT AV NAFTACEN
FI782168A FI782168A (en) 1975-03-13 1978-07-05 SAETT ATT FRAMSTAELLA ETT DERIVAT AV NAFTACEN

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7507893A FR2303552A1 (en) 1975-03-13 1975-03-13 Antitumour naphthacene deriv - prepd. by redn. of carminomycin or culture of Streptomyces microorganisms

Publications (2)

Publication Number Publication Date
FR2303552A1 true FR2303552A1 (en) 1976-10-08
FR2303552B1 FR2303552B1 (en) 1979-08-10

Family

ID=9152527

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7507893A Granted FR2303552A1 (en) 1975-03-13 1975-03-13 Antitumour naphthacene deriv - prepd. by redn. of carminomycin or culture of Streptomyces microorganisms

Country Status (6)

Country Link
AT (1) AT342767B (en)
BE (1) BE839540A (en)
CH (1) CH615222A5 (en)
ES (1) ES446006A1 (en)
FR (1) FR2303552A1 (en)
ZA (1) ZA761526B (en)

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
THE JOURNAL OF ANTIBIOTICS 1974 , PAGES 254.259.) *

Also Published As

Publication number Publication date
AT342767B (en) 1978-04-25
ZA761526B (en) 1977-03-30
CH615222A5 (en) 1980-01-15
ATA185876A (en) 1977-08-15
FR2303552B1 (en) 1979-08-10
ES446006A1 (en) 1977-06-01
BE839540A (en) 1976-09-13

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