FR2315941A2 - Antitumour naphthacene deriv - prepd. by redn. of carminomycin or culture of Streptomyces microorganisms - Google Patents

Antitumour naphthacene deriv - prepd. by redn. of carminomycin or culture of Streptomyces microorganisms

Info

Publication number
FR2315941A2
FR2315941A2 FR7520604A FR7520604A FR2315941A2 FR 2315941 A2 FR2315941 A2 FR 2315941A2 FR 7520604 A FR7520604 A FR 7520604A FR 7520604 A FR7520604 A FR 7520604A FR 2315941 A2 FR2315941 A2 FR 2315941A2
Authority
FR
France
Prior art keywords
redn
deriv
carminomycin
naphthacene
prepd
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7520604A
Other languages
French (fr)
Other versions
FR2315941B2 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc Industries SA
Original Assignee
Rhone Poulenc Industries SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Industries SA filed Critical Rhone Poulenc Industries SA
Priority to FR7520604A priority Critical patent/FR2315941A2/en
Priority to SE7602796A priority patent/SE7602796L/en
Priority to NL7602342A priority patent/NL7602342A/en
Priority to IL49197A priority patent/IL49197A0/en
Priority to AU11900/76A priority patent/AU1190076A/en
Priority to FI760645A priority patent/FI760645A/fi
Priority to GB10045/76A priority patent/GB1510571A/en
Priority to JP51027038A priority patent/JPS51115992A/en
Priority to DE19762610557 priority patent/DE2610557A1/en
Priority to LU74541A priority patent/LU74541A1/xx
Priority to HU76RO883A priority patent/HU175158B/en
Priority to NO760873A priority patent/NO760873L/no
Priority to CA248,335A priority patent/CA1068225A/en
Priority to DK110176A priority patent/DK110176A/en
Priority to NZ180300A priority patent/NZ180300A/en
Priority to ES449770A priority patent/ES449770A1/en
Publication of FR2315941A2 publication Critical patent/FR2315941A2/en
Priority to AT287777A priority patent/AT345451B/en
Priority to FI782168A priority patent/FI782168A/en
Priority to FI782167A priority patent/FI782167A/en
Priority to CH843178A priority patent/CH614974A5/en
Application granted granted Critical
Publication of FR2315941B2 publication Critical patent/FR2315941B2/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The naphthacene deriv. of formula (I) and its acid-addn. salts are new: (I) has antitumour activity against solid and ascitic tumours and is esp. useful for the treatment of human carcinoma. (I) can be prepd. e.g. by microbiological redn. of carminomycin with a culture (or cells or enzymatic extracts isolated therefrom) of Strept. lavendulae ATCC 8664, STrept. roseochromogenes ATCC 13400, Corynebact. simplex ATCC 6946 or Bacterium cyclooxydans ATCC 12673.
FR7520604A 1975-03-13 1975-07-01 Antitumour naphthacene deriv - prepd. by redn. of carminomycin or culture of Streptomyces microorganisms Granted FR2315941A2 (en)

Priority Applications (20)

Application Number Priority Date Filing Date Title
FR7520604A FR2315941A2 (en) 1975-07-01 1975-07-01 Antitumour naphthacene deriv - prepd. by redn. of carminomycin or culture of Streptomyces microorganisms
SE7602796A SE7602796L (en) 1975-06-09 1976-02-27 PROCEDURE FOR PREPARING A NEW NAFTACENDER DERIVATIVE
NL7602342A NL7602342A (en) 1975-03-13 1976-03-05 NAFTACEEN DERIVATIVE WITH ANTIBIOTIC ACTIVITY.
AU11900/76A AU1190076A (en) 1975-03-13 1976-03-11 Antibiotic
IL49197A IL49197A0 (en) 1975-03-13 1976-03-11 An antibiotic designated 32,999 rp,processes for the preparation thereof and pharmaceutical compositions containing the same
NZ180300A NZ180300A (en) 1975-03-13 1976-03-12 Antibiotic 32,999 rp produced by microbiological reduction and by cultivation of streptomyces coeruleorubidus(nrrl 3046,nrrl o045nrrl 8098)strepthomyces bifurcus(nrrl3539)andstreptomyces atroviolaceus(nrrl 8148)
JP51027038A JPS51115992A (en) 1975-03-13 1976-03-12 Novel antibiotic
DE19762610557 DE2610557A1 (en) 1975-03-13 1976-03-12 NEW NAPHTHACEN DERIVATIVE, ITS MANUFACTURING AND COMPOSITIONS CONTAINING IT
LU74541A LU74541A1 (en) 1975-03-13 1976-03-12
HU76RO883A HU175158B (en) 1975-03-13 1976-03-12 Process for producing naphtacene derivatives
FI760645A FI760645A (en) 1975-03-13 1976-03-12
CA248,335A CA1068225A (en) 1975-03-13 1976-03-12 Naphtacene derivatives, their preparation and compounds thereof
DK110176A DK110176A (en) 1975-03-13 1976-03-12 PROCEDURE FOR PREPARING A NAPHTHACENE DERIVATIVE
GB10045/76A GB1510571A (en) 1975-03-13 1976-03-12 Aminoglycosidic antibiotic
NO760873A NO760873L (en) 1975-03-13 1976-03-12
ES449770A ES449770A1 (en) 1975-07-01 1976-07-12 Antitumour naphthacene deriv - prepd. by redn. of carminomycin or culture of Streptomyces microorganisms
AT287777A AT345451B (en) 1975-07-01 1977-04-25 PROCESS FOR PREPARING A NEW ANTIBIOTIC
FI782168A FI782168A (en) 1975-03-13 1978-07-05 SAETT ATT FRAMSTAELLA ETT DERIVAT AV NAFTACEN
FI782167A FI782167A (en) 1975-03-13 1978-07-05 SAETT ATT FRAMSTAELLA ETT DERIVAT AV NAFTACEN
CH843178A CH614974A5 (en) 1975-07-01 1978-08-08 Process for the preparation of a new naphthacene derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7520604A FR2315941A2 (en) 1975-07-01 1975-07-01 Antitumour naphthacene deriv - prepd. by redn. of carminomycin or culture of Streptomyces microorganisms

Publications (2)

Publication Number Publication Date
FR2315941A2 true FR2315941A2 (en) 1977-01-28
FR2315941B2 FR2315941B2 (en) 1979-09-14

Family

ID=9157326

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7520604A Granted FR2315941A2 (en) 1975-03-13 1975-07-01 Antitumour naphthacene deriv - prepd. by redn. of carminomycin or culture of Streptomyces microorganisms

Country Status (3)

Country Link
CH (1) CH614974A5 (en)
ES (1) ES449770A1 (en)
FR (1) FR2315941A2 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1911240A1 (en) * 1968-03-05 1969-10-02 Rhone Poulenc Sa New antibiotic and its manufacture
DE1957980A1 (en) * 1968-11-18 1970-08-13 Rhone Poulenc Sa Process for the production of daunorubicin by culturing a Streptomyces

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1911240A1 (en) * 1968-03-05 1969-10-02 Rhone Poulenc Sa New antibiotic and its manufacture
DE1957980A1 (en) * 1968-11-18 1970-08-13 Rhone Poulenc Sa Process for the production of daunorubicin by culturing a Streptomyces

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS 79-124691B 1973 CITE USSR. NO. 324 770 KRUGLYAK ) *

Also Published As

Publication number Publication date
CH614974A5 (en) 1979-12-28
ES449770A1 (en) 1978-02-16
FR2315941B2 (en) 1979-09-14

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