FR2302728A1 - Procede de production de composes de butyrophenone, nouveaux produits ainsi obtenus et leur utilisation comme agents presentant une activite de depression du systeme nerveux central - Google Patents
Procede de production de composes de butyrophenone, nouveaux produits ainsi obtenus et leur utilisation comme agents presentant une activite de depression du systeme nerveux centralInfo
- Publication number
- FR2302728A1 FR2302728A1 FR7606032A FR7606032A FR2302728A1 FR 2302728 A1 FR2302728 A1 FR 2302728A1 FR 7606032 A FR7606032 A FR 7606032A FR 7606032 A FR7606032 A FR 7606032A FR 2302728 A1 FR2302728 A1 FR 2302728A1
- Authority
- FR
- France
- Prior art keywords
- depression
- agents
- production
- nervous system
- central nervous
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
- C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/30—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
- C07D211/32—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/52—Oxygen atoms attached in position 4 having an aryl radical as the second substituent in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7704815A FR2338260A1 (fr) | 1975-03-05 | 1977-02-18 | Procede de preparation de composes de butyrophenone a groupe piperidino, morpholino, pyrrolidino ou piperazino et nouveaux produits ainsi obtenus, a activite psychotrope |
| FR7704817A FR2338245A1 (fr) | 1975-03-05 | 1977-02-18 | Procede de preparation de composes de buthyrophenone a groupe cyclohexylamine ou phenoxyalkylamino et nouveaux produits ainsi obtenus, a activite psychotrope |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP50027489A JPS51125239A (en) | 1975-03-05 | 1975-03-05 | Process for preparing new bytyrophenone derivatives |
| JP50138836A JPS596304B2 (ja) | 1975-11-18 | 1975-11-18 | シンキナブチロフエノンユウドウタイノセイホウ |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2302728A1 true FR2302728A1 (fr) | 1976-10-01 |
| FR2302728B1 FR2302728B1 (US08088918-20120103-C00476.png) | 1979-10-05 |
Family
ID=26365419
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7606032A Granted FR2302728A1 (fr) | 1975-03-05 | 1976-03-03 | Procede de production de composes de butyrophenone, nouveaux produits ainsi obtenus et leur utilisation comme agents presentant une activite de depression du systeme nerveux central |
Country Status (20)
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4894461A (en) * | 1981-04-27 | 1990-01-16 | Hoechst-Roussel Pharmaceuticals, Inc. | 3-(γ-chloropropyl)-6-fluoro-1,2-benzisoxazole |
| US4396770A (en) * | 1982-04-09 | 1983-08-02 | Hoechst-Roussel Pharmaceuticals Inc. | 1-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-4-hydroxy-4-phenylpiperidines |
| IL66866A (en) * | 1982-04-09 | 1987-08-31 | Hoechst Roussel Pharma | 1-(3-(6-fluoro-1,2-benzisoxazol-3-yl)propyl)-4-(substituted)-piperazines and-piperidines,a process for the preparation thereof,and pharmaceutical compositions containing them |
| US4610988A (en) * | 1982-04-09 | 1986-09-09 | Hoechst-Roussel Pharmaceuticals Inc. | 1-[3-(6-fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(substituted)piperazines useful for alleviating pain |
| US4390544A (en) * | 1982-04-09 | 1983-06-28 | Hoechst-Roussel Pharmaceuticals Inc. | {1-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(2-oxo-1-benzimidazolinyl}p |
| US4609658A (en) * | 1982-04-09 | 1986-09-02 | Hoechst-Roussel Pharmaceuticals Inc. | 1-[3-(6-fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(substituted) piperazines useful for reducing blood pressure |
| US4374245A (en) * | 1982-04-09 | 1983-02-15 | Hoechst-Roussel Pharmaceuticals Inc. | 8-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one |
| US4536578A (en) * | 1982-04-09 | 1985-08-20 | Hoechst-Roussel Pharmaceuticals Inc. | 1-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(substituted)piperazines |
| US4458075A (en) * | 1982-04-09 | 1984-07-03 | Hoechst-Roussel Pharmaceuticals Inc. | 6-Fluoro-3-[3-(1-heterocyclo)propyl]-1,2-benzisoxazoles |
| US4420485A (en) * | 1982-09-29 | 1983-12-13 | Hoechst-Roussel Pharmaceuticals Inc. | 1'-[3-(1,2-Benzisoxazol-3-yl) proply]spiro[benzofuran-2(3H),3' or 4'-piperidines or 3'-pyrrolidines] |
| KR910006138B1 (ko) * | 1986-09-30 | 1991-08-16 | 에자이 가부시끼가이샤 | 환상아민 유도체 |
| EP0661266A1 (en) * | 1993-12-27 | 1995-07-05 | Toa Eiyo Ltd. | Substituted cyclic amine compounds as 5HT2 antagonists |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3799932A (en) * | 1970-03-20 | 1974-03-26 | Sumitomo Chemical Co | Gamma-piperidinobutyrophenones |
| JPS4718878U (US08088918-20120103-C00476.png) * | 1971-04-05 | 1972-11-02 | ||
| JPS5755714B2 (US08088918-20120103-C00476.png) * | 1972-03-18 | 1982-11-25 |
-
1976
- 1976-02-19 FI FI760415A patent/FI60390C/fi not_active IP Right Cessation
- 1976-02-20 SE SE7602049A patent/SE7602049L/xx not_active Application Discontinuation
- 1976-02-27 CS CS761296A patent/CS188131B2/cs unknown
- 1976-03-02 BE BE164777A patent/BE839097A/xx not_active IP Right Cessation
- 1976-03-02 GB GB8171/76A patent/GB1506805A/en not_active Expired
- 1976-03-02 CA CA246,882A patent/CA1077039A/en not_active Expired
- 1976-03-03 DE DE19762608801 patent/DE2608801A1/de not_active Withdrawn
- 1976-03-03 AT AT155776A patent/AT346341B/de not_active IP Right Cessation
- 1976-03-03 CH CH265176A patent/CH611598A5/xx not_active IP Right Cessation
- 1976-03-03 FR FR7606032A patent/FR2302728A1/fr active Granted
- 1976-03-04 MX MX000037U patent/MX3392E/es unknown
- 1976-03-04 ES ES445775A patent/ES445775A1/es not_active Expired
- 1976-03-04 DK DK93976*#A patent/DK93976A/da not_active Application Discontinuation
- 1976-03-05 PL PL1976187731A patent/PL106528B1/pl unknown
- 1976-03-05 AR AR262454A patent/AR211006A1/es active
- 1976-03-05 HU HU76SU911A patent/HU175175B/hu unknown
- 1976-03-05 AU AU11730/76A patent/AU503943B2/en not_active Ceased
- 1976-03-05 NL NL7602370A patent/NL7602370A/xx not_active Application Discontinuation
- 1976-03-05 DD DD191722A patent/DD124116A5/xx unknown
-
1978
- 1978-10-17 US US05/952,104 patent/US4235914A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CS188131B2 (en) | 1979-02-28 |
| DE2608801A1 (de) | 1976-09-16 |
| SE7602049L (sv) | 1976-09-06 |
| HU175175B (hu) | 1980-05-28 |
| CA1077039A (en) | 1980-05-06 |
| FR2302728B1 (US08088918-20120103-C00476.png) | 1979-10-05 |
| ATA155776A (de) | 1978-03-15 |
| AT346341B (de) | 1978-11-10 |
| FI60390C (fi) | 1982-01-11 |
| AR211006A1 (es) | 1977-10-14 |
| AU1173076A (en) | 1977-09-08 |
| MX3392E (es) | 1980-10-28 |
| PL106528B1 (pl) | 1979-12-31 |
| AU503943B2 (en) | 1979-09-27 |
| US4235914A (en) | 1980-11-25 |
| ES445775A1 (es) | 1977-10-16 |
| GB1506805A (en) | 1978-04-12 |
| FI760415A (US08088918-20120103-C00476.png) | 1976-09-06 |
| DK93976A (da) | 1976-09-06 |
| NL7602370A (nl) | 1976-09-07 |
| FI60390B (fi) | 1981-09-30 |
| CH611598A5 (US08088918-20120103-C00476.png) | 1979-06-15 |
| DD124116A5 (US08088918-20120103-C00476.png) | 1977-02-02 |
| BE839097A (fr) | 1976-09-02 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| FR2339636A1 (fr) | Procede de production de polyesters aromatiques et nouveaux produits ainsi obtenus | |
| BE872210A (fr) | Procede de preparation de nitrodiarylamines et nouveaux produits ainsi obtenus | |
| FR2345452A1 (fr) | Procede de preparation d'arylmalonamido-1-oxadethiacephalosporines et nouveaux produits ainsi obtenus, a activite antibacterienne | |
| BE860971A (fr) | Procede de preparation de n,n'-methylenebis-(0,0-diaryl n-phosphonomethylglycinonitriles, nouveaux produits ainsi obtenus et leur utilisation | |
| FR2322876A1 (fr) | Procede de production de produits carbones poreux et nouveaux produits ainsi obtenus | |
| FR2306214A1 (fr) | Procede de preparation de 17 a-ester-21-halopregnanes et nouveaux produits ainsi obtenus | |
| FR2302728A1 (fr) | Procede de production de composes de butyrophenone, nouveaux produits ainsi obtenus et leur utilisation comme agents presentant une activite de depression du systeme nerveux central | |
| BE852194A (fr) | Procede de preparation de composes d'acide 3-cephem-4- carboxylique 3,7-disubstitue et nouveaux produits ainsi obtenus | |
| BE842066A (fr) | Procede de preparation de composes de n-(perfluoroacyl)- n-phosphonomethylglycine et nouveaux produits ainsi obtenus, utilises comme herbicides | |
| FR2276828A1 (fr) | Procede de production de derives d'alkylamino-glucopyranoside, nouveaux produits ainsi obtenus et leur utilisation pour leur activite anticancer | |
| BE837479A (fr) | Procede de production de produits a faible poids specifique apparent a partir de bicarbonate de sodium et nouveaux produits ainsi obtenus | |
| BE887994A (fr) | Procede de preparation de 2-haloacetamides a substition n-methyleneether et nouveaux produits ainsi obtenus | |
| BE854167A (fr) | Procede de preparation de derives de n-phosphono-methylglycine, nouveaux produits ainsi obtenus et leur utilisation comme herbicides | |
| FR2317924A1 (fr) | Procede de production de derives d'ortho-aminobutyrophenone, nouveaux produits ainsi obtenus et leur utilisation comme agents analgesiques et antipsychose | |
| FR2294182A1 (fr) | Procede de production de carbonylaldiminomethanephosphonates et nouveaux produits ainsi obtenus | |
| FR2319626A1 (fr) | Procede de preparation de dinitriles insatures et nouveaux produits ainsi obtenus | |
| FR2328003A1 (fr) | Procede de production de copolymeres sequences ethylene-propylene et nouveaux produits ainsi obtenus | |
| FR2313393A1 (fr) | Procede de preparation de phosphinates et nouveaux produits ainsi obtenus | |
| BE846898A (fr) | Procede pour la production de charbon actif et produits ainsi obtenus, | |
| FR2342958A1 (fr) | Procede de production de derives d'o-aminophenylcetone et nouveaux produits ainsi obtenus | |
| FR2296412A1 (fr) | Procede de production de composes de morpholine et nouveaux produits ainsi obtenus, a activite sur le systeme nerveux central | |
| FR2352820A1 (fr) | Procede de preparation de composes de 7-aminocephem en utilisant des champignons de moisissures et nouveaux produits ainsi obtenus | |
| FR2323391A1 (fr) | Procede de production de derives de 1,5-dihydro-2h-1,4-benzodiazepin-2-one, nouveaux produits ainsi obtenus et leur utilisation pharmaceutique, notamment comme produits sedatifs et hypnotiques | |
| FR2312508A1 (fr) | Procede de production de monopalmitates de sterylglucosides amorphes facilement absorbables et nouveaux produits ainsi obtenus | |
| FR2291763A1 (fr) | Procede de preparation de derives cycliques de phosphamide, nouveaux produits ainsi obtenus et leur utilisation comme agents antitumeurs et d'immunosuppression |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |