FR2301265A1 - Aminocyclitols antibiotiques et leurs procedes de preparation - Google Patents

Aminocyclitols antibiotiques et leurs procedes de preparation

Info

Publication number
FR2301265A1
FR2301265A1 FR7604291A FR7604291A FR2301265A1 FR 2301265 A1 FR2301265 A1 FR 2301265A1 FR 7604291 A FR7604291 A FR 7604291A FR 7604291 A FR7604291 A FR 7604291A FR 2301265 A1 FR2301265 A1 FR 2301265A1
Authority
FR
France
Prior art keywords
aminocyclitols
antibiotics
preparation methods
preparation
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7604291A
Other languages
English (en)
Other versions
FR2301265B1 (fr
Inventor
Sol Jacob Daum
Robert La Grone Clarke
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
STWB Inc
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/550,273 external-priority patent/US3972930A/en
Priority claimed from US05/615,593 external-priority patent/US3982996A/en
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Publication of FR2301265A1 publication Critical patent/FR2301265A1/fr
Application granted granted Critical
Publication of FR2301265B1 publication Critical patent/FR2301265B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • C07H15/236—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2 a saccharide radical being substituted by an alkylamino radical in position 3 and by two substituents different from hydrogen in position 4, e.g. gentamicin complex, sisomicin, verdamycin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
    • C07C45/57—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom
    • C07C45/58—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom in three-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/385—Saturated compounds containing a keto group being part of a ring
    • C07C49/487—Saturated compounds containing a keto group being part of a ring containing hydroxy groups
    • C07C49/497—Saturated compounds containing a keto group being part of a ring containing hydroxy groups a keto group being part of a six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/14—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by free hydroxyl radicals
FR7604291A 1975-02-18 1976-02-17 Aminocyclitols antibiotiques et leurs procedes de preparation Granted FR2301265A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/550,273 US3972930A (en) 1975-02-18 1975-02-18 Aminocyclitol antibiotics
US05/615,593 US3982996A (en) 1975-09-22 1975-09-22 Process for preparing aminocyclitol antibiotics

Publications (2)

Publication Number Publication Date
FR2301265A1 true FR2301265A1 (fr) 1976-09-17
FR2301265B1 FR2301265B1 (fr) 1979-05-25

Family

ID=27069389

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7604291A Granted FR2301265A1 (fr) 1975-02-18 1976-02-17 Aminocyclitols antibiotiques et leurs procedes de preparation

Country Status (21)

Country Link
JP (1) JPS51108041A (fr)
AR (3) AR221027A1 (fr)
AU (1) AU503105B2 (fr)
CA (1) CA1061731A (fr)
CH (3) CH617964A5 (fr)
DE (1) DE2606517A1 (fr)
DK (1) DK143111C (fr)
EG (1) EG12994A (fr)
ES (1) ES445274A1 (fr)
FI (1) FI56026C (fr)
FR (1) FR2301265A1 (fr)
GB (1) GB1529376A (fr)
GR (1) GR60050B (fr)
IE (1) IE42807B1 (fr)
IL (1) IL49053A (fr)
IN (2) IN147046B (fr)
NL (1) NL7601655A (fr)
NO (3) NO147308C (fr)
NZ (1) NZ180036A (fr)
PT (1) PT64816B (fr)
SE (2) SE7601810L (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE476970A (fr) * 1946-10-24
UA97245C2 (en) 2006-06-02 2012-01-25 Меиджи Сеика Фарма Ко., Лтд. Aminoglycoside antibiotics

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7410364A (nl) * 1973-08-06 1975-02-10 Scherico Ltd Werkwijze ter bereiding van antibiotische ver- bindingen en preparaten die deze verbindingen als actieve component bevatten.

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7410364A (nl) * 1973-08-06 1975-02-10 Scherico Ltd Werkwijze ter bereiding van antibiotische ver- bindingen en preparaten die deze verbindingen als actieve component bevatten.

Also Published As

Publication number Publication date
NO148298C (no) 1983-09-14
IE42807B1 (en) 1980-10-22
EG12994A (en) 1980-07-31
NO803185L (no) 1976-08-19
DK143111B (da) 1981-03-30
IL49053A (en) 1979-11-30
NZ180036A (en) 1979-10-25
JPS51108041A (fr) 1976-09-25
CH617964A5 (en) 1980-06-30
CH618215A5 (en) 1980-07-15
NO820574L (no) 1976-08-19
PT64816B (en) 1978-07-03
NO147308B (no) 1982-12-06
AU1117776A (en) 1977-08-25
IL49053A0 (en) 1976-04-30
NO147308C (no) 1983-03-16
CH618214A5 (en) 1980-07-15
IN149240B (fr) 1981-10-10
DE2606517A1 (de) 1976-08-26
AU503105B2 (en) 1979-08-23
NL7601655A (nl) 1976-08-20
ES445274A1 (es) 1977-06-16
GR60050B (en) 1978-04-04
SE7601810L (sv) 1976-08-19
NO760472L (fr) 1976-08-19
IE42807L (en) 1976-08-18
AR227266A1 (es) 1982-10-15
SE8007540L (sv) 1980-10-27
CA1061731A (fr) 1979-09-04
DK143111C (da) 1981-11-16
PT64816A (en) 1976-03-01
IN147046B (fr) 1979-10-27
AR217417A1 (es) 1980-03-31
NO146811B (no) 1982-09-06
FI56026B (fi) 1979-07-31
FI760387A (fr) 1976-08-19
FI56026C (fi) 1979-11-12
AR221027A1 (es) 1980-12-30
NO146811C (no) 1982-12-15
DK63176A (da) 1976-08-19
NO148298B (no) 1983-06-06
FR2301265B1 (fr) 1979-05-25
GB1529376A (en) 1978-10-18

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Legal Events

Date Code Title Description
ST Notification of lapse