FR22C1022I1 - Composes, compositions et procedes permettant de traiter et de prevenir des infections a orthopoxvirus et des maladies associees - Google Patents

Composes, compositions et procedes permettant de traiter et de prevenir des infections a orthopoxvirus et des maladies associees

Info

Publication number
FR22C1022I1
FR22C1022I1 FR22C1022C FR22C1022C FR22C1022I1 FR 22C1022 I1 FR22C1022 I1 FR 22C1022I1 FR 22C1022 C FR22C1022 C FR 22C1022C FR 22C1022 C FR22C1022 C FR 22C1022C FR 22C1022 I1 FR22C1022 I1 FR 22C1022I1
Authority
FR
France
Prior art keywords
compositions
treating
compounds
preventing
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR22C1022C
Other languages
English (en)
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siga Technologies Inc
Original Assignee
Siga Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Siga Technologies Inc filed Critical Siga Technologies Inc
Publication of FR22C1022I1 publication Critical patent/FR22C1022I1/fr
Active legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/58—[b]- or [c]-condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
FR22C1022C 2003-06-20 2022-06-02 Composes, compositions et procedes permettant de traiter et de prevenir des infections a orthopoxvirus et des maladies associees Active FR22C1022I1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48018203P 2003-06-20 2003-06-20
PCT/US2004/019552 WO2004112718A2 (en) 2003-06-20 2004-06-18 Compounds, compositions and methods for treatment and prevention of orthopoxvirus infections and associated diseases

Publications (1)

Publication Number Publication Date
FR22C1022I1 true FR22C1022I1 (fr) 2022-07-22

Family

ID=33539267

Family Applications (1)

Application Number Title Priority Date Filing Date
FR22C1022C Active FR22C1022I1 (fr) 2003-06-20 2022-06-02 Composes, compositions et procedes permettant de traiter et de prevenir des infections a orthopoxvirus et des maladies associees

Country Status (11)

Country Link
EP (1) EP1638938B1 (enrdf_load_stackoverflow)
JP (2) JP4884216B2 (enrdf_load_stackoverflow)
AU (1) AU2004249250C1 (enrdf_load_stackoverflow)
BE (1) BE2022C521I2 (enrdf_load_stackoverflow)
CA (1) CA2529761C (enrdf_load_stackoverflow)
DK (1) DK1638938T3 (enrdf_load_stackoverflow)
ES (1) ES2632313T3 (enrdf_load_stackoverflow)
FR (1) FR22C1022I1 (enrdf_load_stackoverflow)
NL (1) NL301177I2 (enrdf_load_stackoverflow)
PL (1) PL1638938T3 (enrdf_load_stackoverflow)
WO (1) WO2004112718A2 (enrdf_load_stackoverflow)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2012268859B2 (en) * 2003-06-20 2016-05-05 Siga Technologies, Inc. Chemicals, compositions, and methods for treatment and prevention of orthopoxvirus infections and associated diseases
US7737168B2 (en) 2003-06-20 2010-06-15 Siga Technologies, Inc. Compounds, compositions, and methods for treatment and prevention of orthopoxvirus infections and associated diseases
DK1638938T3 (en) * 2003-06-20 2017-07-31 Siga Tech Inc Compounds, Compositions and Methods for the Treatment and Prevention of Orthopox Virus Infections and Related Diseases
US8530509B2 (en) 2003-06-20 2013-09-10 Siga Technologies, Inc. Compounds, compositions and methods for treatment and prevention of orthopoxvirus infections and associated diseases
US8563591B2 (en) * 2004-08-30 2013-10-22 Janssen Pharmaceutica N.V. Tricyclic lactam derivatives as 11-beta hydroxysteroid dehydrogenase inhibitors
US8410149B2 (en) 2004-12-06 2013-04-02 Siga Technologies Inc. Sulfonyl semicarbazides, semicarbazides and ureas, pharmaceutical compositions thereof, and methods for treating hemorrhagic fever viruses, including infections associated with arenaviruses
CA2590962A1 (en) 2004-12-06 2006-06-15 Siga Technologies, Inc. Sulfonyl semicarbazides, semicarbazides and ureas, pharmaceutical compositions thereof, and methods for treating hemorrhagic fever viruses, including infections associated with arenaviruses
US7994221B2 (en) 2004-12-06 2011-08-09 Siga Technologies, Inc. Sulfonyl semicarbazides, carbonyl semicarbazides, semicarbazides and ureas, pharmaceutical compositions thereof, and methods for treating hemorrhagic fever viruses, including infections associated with arenaviruses
US20070003608A1 (en) * 2005-04-08 2007-01-04 Almond Merrick R Compounds, compositions and methods for the treatment of viral infections and other medical disorders
US8642577B2 (en) * 2005-04-08 2014-02-04 Chimerix, Inc. Compounds, compositions and methods for the treatment of poxvirus infections
CN104758281A (zh) 2007-04-23 2015-07-08 西佳技术公司 用于治疗和预防正痘病毒感染和相关疾病的化合物、组合物和方法
US8993542B2 (en) 2008-01-25 2015-03-31 Chimerix Inc. Methods of treating viral infections
WO2011011519A1 (en) 2009-07-21 2011-01-27 Chimerix, Inc. Compounds, compositions and methods for treating ocular conditions
RU2412168C1 (ru) * 2009-12-02 2011-02-20 Федеральное государственное учреждение науки "Государственный научный центр вирусологии и биотехнологии "Вектор" Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека (ФГУН ГНЦ ВБ "Вектор" Роспотребнадзора) Гидрат n-{3,5-диоксо-4-азатетрацикло[5.3.2.02,6.08,10]додец-11-ен-4-ил}-2-гидроксибензамида, обладающий противовирусной активностью в отношении ортопоксвирусов
RU2412167C1 (ru) * 2009-12-02 2011-02-20 Федеральное государственное учреждение науки "Государственный научный центр вирусологии и биотехнологии "Вектор" Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека (ФГУН ГНЦ ВБ "Вектор" Роспотребнадзора) {3,5-диоксо-4-азатетрацикло[5.3.2.02,6.08,10]додец-11-ен-4-ил}тиомочевина, обладающая противовирусной активностью в отношении ортопоксвирусов
AU2011216243B2 (en) 2010-02-12 2015-07-09 Chimerix, Inc. Nucleoside phosphonate salts
RU2578606C2 (ru) * 2010-03-23 2016-03-27 Сига Текнолоджиз, Инк Полиморфные формы соединения st-246 и способы получения
EP2563367A4 (en) 2010-04-26 2013-12-04 Chimerix Inc Methods of treating retroviral infections and related dosage regimes
DK2600715T3 (da) 2010-08-05 2020-03-16 Siga Tech Inc Flydende ST-246-formuleringer og fremgangsmåder
CN101906064A (zh) * 2010-08-09 2010-12-08 中国人民解放军军事医学科学院微生物流行病研究所 St-246的立体异构体的制备方法
RU2440983C1 (ru) * 2010-09-28 2012-01-27 Новосибирский институт органической химии им. Н.Н. Ворожцова Сибирского отделения Российской академии наук (НИОХ СО РАН) Метил, хлор и нитропроизводные n-{3, 5-диоксо-4-азатетрацикло[5.3.2.02,6.08,10]додец-11-ен-4-ил}-2-гидроксибензамида-противовирусные препараты, ингибирующие репликацию различных видов ортопоксвирусов
EP3321253B1 (en) * 2012-08-16 2020-02-12 Siga Technologies, Inc. Method of preparing tecovirimat
CA2917199C (en) * 2013-07-19 2021-08-31 Siga Technologies, Inc. Amorphous tecovirimat preparation
IL315763A (en) * 2022-03-27 2024-11-01 Univ Texas Small molecule inhibitors of lanostral synthase
CN116730995B (zh) * 2022-08-12 2024-06-25 深圳微芯生物科技股份有限公司 一类酰肼类化合物、其制备方法及其应用
CN116003309B (zh) * 2022-08-12 2025-03-04 深圳微芯生物科技股份有限公司 一类酰肼类化合物、其制备方法及其应用

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Publication number Priority date Publication date Assignee Title
US2906755A (en) * 1956-11-16 1959-09-29 Schenley Ind Inc N-acyl derivatives of alpha-pyridine carboxylic acid hydrazide
US4061763A (en) * 1975-05-09 1977-12-06 Merck & Co., Inc. Tricyclicdicarboximides
JPS5247844A (en) * 1975-10-15 1977-04-16 Ube Ind Ltd Elastomer compositions
JPS6483065A (en) * 1987-09-25 1989-03-28 Hitachi Chemical Co Ltd Endo-cis-3,6-cyclopropylene-tetra(or hexa)hydrophthalic acid imide derivative and antiarhythmic agent
US5068356A (en) * 1990-02-20 1991-11-26 Atochem North America, Inc. Hindered phenolic n-(amido)imides
US6596771B2 (en) 2001-01-12 2003-07-22 Schering Corporation Drugs for treating viral infections
US6433016B1 (en) * 2001-01-12 2002-08-13 Vassil Stefanov Georgiev Drugs for treating viral infections
US20040087548A1 (en) * 2001-02-27 2004-05-06 Salvati Mark E. Fused cyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
DK1638938T3 (en) * 2003-06-20 2017-07-31 Siga Tech Inc Compounds, Compositions and Methods for the Treatment and Prevention of Orthopox Virus Infections and Related Diseases

Also Published As

Publication number Publication date
ES2632313T3 (es) 2017-09-12
JP2011252019A (ja) 2011-12-15
JP4884216B2 (ja) 2012-02-29
BE2022C521I2 (enrdf_load_stackoverflow) 2024-04-23
DK1638938T3 (en) 2017-07-31
EP1638938A4 (en) 2008-09-17
AU2004249250A1 (en) 2004-12-29
JP5657489B2 (ja) 2015-01-21
NL301177I1 (nl) 2022-06-08
AU2004249250B2 (en) 2011-09-01
EP1638938A2 (en) 2006-03-29
EP1638938B1 (en) 2017-04-12
NL301177I2 (nl) 2022-08-23
CA2529761C (en) 2013-08-13
WO2004112718A2 (en) 2004-12-29
WO2004112718A3 (en) 2005-04-07
AU2004249250C1 (en) 2012-04-12
CA2529761A1 (en) 2004-12-29
PL1638938T3 (pl) 2017-10-31
JP2007521273A (ja) 2007-08-02

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