NL301177I2 - tecovirimat of een farmaceutisch aanvaardbaar zout daarvan - Google Patents

tecovirimat of een farmaceutisch aanvaardbaar zout daarvan

Info

Publication number
NL301177I2
NL301177I2 NL301177C NL301177C NL301177I2 NL 301177 I2 NL301177 I2 NL 301177I2 NL 301177 C NL301177 C NL 301177C NL 301177 C NL301177 C NL 301177C NL 301177 I2 NL301177 I2 NL 301177I2
Authority
NL
Netherlands
Prior art keywords
tecovirimat
pharmaceutically acceptable
acceptable salt
salt
pharmaceutically
Prior art date
Application number
NL301177C
Other languages
English (en)
Other versions
NL301177I1 (nl
Original Assignee
Siga Tech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Siga Tech Inc filed Critical Siga Tech Inc
Publication of NL301177I1 publication Critical patent/NL301177I1/nl
Publication of NL301177I2 publication Critical patent/NL301177I2/nl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/58[b]- or [c]-condensed
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NL301177C 2003-06-20 2022-06-02 tecovirimat of een farmaceutisch aanvaardbaar zout daarvan NL301177I2 (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48018203P 2003-06-20 2003-06-20
PCT/US2004/019552 WO2004112718A2 (en) 2003-06-20 2004-06-18 Compounds, compositions and methods for treatment and prevention of orthopoxvirus infections and associated diseases

Publications (2)

Publication Number Publication Date
NL301177I1 NL301177I1 (nl) 2022-06-08
NL301177I2 true NL301177I2 (nl) 2022-08-23

Family

ID=33539267

Family Applications (1)

Application Number Title Priority Date Filing Date
NL301177C NL301177I2 (nl) 2003-06-20 2022-06-02 tecovirimat of een farmaceutisch aanvaardbaar zout daarvan

Country Status (11)

Country Link
EP (1) EP1638938B1 (nl)
JP (2) JP4884216B2 (nl)
AU (1) AU2004249250C1 (nl)
BE (1) BE2022C521I2 (nl)
CA (1) CA2529761C (nl)
DK (1) DK1638938T3 (nl)
ES (1) ES2632313T3 (nl)
FR (1) FR22C1022I1 (nl)
NL (1) NL301177I2 (nl)
PL (1) PL1638938T3 (nl)
WO (1) WO2004112718A2 (nl)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2007351866C1 (en) * 2003-06-20 2013-07-25 Siga Technologies, Inc. Chemicals, compositions, and methods for treatment and prevention of orthopoxvirus infections and associated diseases
US7737168B2 (en) * 2003-06-20 2010-06-15 Siga Technologies, Inc. Compounds, compositions, and methods for treatment and prevention of orthopoxvirus infections and associated diseases
US8530509B2 (en) 2003-06-20 2013-09-10 Siga Technologies, Inc. Compounds, compositions and methods for treatment and prevention of orthopoxvirus infections and associated diseases
AU2012268859B2 (en) * 2003-06-20 2016-05-05 Siga Technologies, Inc. Chemicals, compositions, and methods for treatment and prevention of orthopoxvirus infections and associated diseases
ES2632313T3 (es) * 2003-06-20 2017-09-12 Siga Technologies Inc. Compuestos, composiciones y métodos para el tratamiento y la prevención de infecciones por ortopoxvirus y enfermedades asociadas
RU2386617C2 (ru) * 2004-08-30 2010-04-20 Янссен Фармацевтика Н.В. ПРОИЗВОДНЫЕ ТРИЦИКЛИЧЕСКОГО ЛАКТАМА В КАЧЕСТВЕ ИНГИБИТОРОВ 11-β-ГИДРОКСИСТЕРОИДНОЙ ДЕГИДРОГЕНАЗЫ
US7994221B2 (en) 2004-12-06 2011-08-09 Siga Technologies, Inc. Sulfonyl semicarbazides, carbonyl semicarbazides, semicarbazides and ureas, pharmaceutical compositions thereof, and methods for treating hemorrhagic fever viruses, including infections associated with arenaviruses
JP5285276B2 (ja) 2004-12-06 2013-09-11 シガ テクノロジーズ,インコーポレーテッド アレナウイルスに関連した感染をはじめとする出血熱ウイルスを処置するための、スルホニルセミカルバジド、セミカルバジドおよび尿素、その医薬組成物および方法
US8410149B2 (en) 2004-12-06 2013-04-02 Siga Technologies Inc. Sulfonyl semicarbazides, semicarbazides and ureas, pharmaceutical compositions thereof, and methods for treating hemorrhagic fever viruses, including infections associated with arenaviruses
US20070003608A1 (en) * 2005-04-08 2007-01-04 Almond Merrick R Compounds, compositions and methods for the treatment of viral infections and other medical disorders
JP2008535862A (ja) * 2005-04-08 2008-09-04 キメリクス,インコーポレイテッド ポックスウイルス感染の治療のための化合物、組成物および方法
EP3085377A1 (en) 2008-01-25 2016-10-26 Chimerix, Inc. Methods of treating viral infections
WO2011011519A1 (en) 2009-07-21 2011-01-27 Chimerix, Inc. Compounds, compositions and methods for treating ocular conditions
WO2011100698A2 (en) 2010-02-12 2011-08-18 Chimerix, Inc. Methods of treating viral infection
JP6018041B2 (ja) 2010-03-23 2016-11-02 シガ・テクノロジーズ・インコーポレーテッド St−246の多形型および調製方法
WO2011139709A2 (en) 2010-04-26 2011-11-10 Chimerix, Inc. Methods of treating retroviral infections and related dosage regimes
EP2600715B1 (en) 2010-08-05 2019-12-11 Siga Technologies, Inc. St-246 liquid formulations and methods
CN101906064A (zh) * 2010-08-09 2010-12-08 中国人民解放军军事医学科学院微生物流行病研究所 St-246的立体异构体的制备方法
CA3183432A1 (en) 2012-08-16 2014-02-20 Siga Technologies, Inc. Methods of preparing tecovirimat
CN111635353A (zh) * 2013-07-19 2020-09-08 西佳技术公司 非晶形特考韦瑞制备
WO2023192782A2 (en) * 2022-03-27 2023-10-05 Board Of Regents, The University Of Texas System Small molecule inhibitors of lanosterol synthase
CN116730995B (zh) * 2022-08-12 2024-06-25 深圳微芯生物科技股份有限公司 一类酰肼类化合物、其制备方法及其应用

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2906755A (en) * 1956-11-16 1959-09-29 Schenley Ind Inc N-acyl derivatives of alpha-pyridine carboxylic acid hydrazide
US4061763A (en) * 1975-05-09 1977-12-06 Merck & Co., Inc. Tricyclicdicarboximides
JPS5247844A (en) * 1975-10-15 1977-04-16 Ube Ind Ltd Elastomer compositions
JPS6483065A (en) * 1987-09-25 1989-03-28 Hitachi Chemical Co Ltd Endo-cis-3,6-cyclopropylene-tetra(or hexa)hydrophthalic acid imide derivative and antiarhythmic agent
US5068356A (en) * 1990-02-20 1991-11-26 Atochem North America, Inc. Hindered phenolic n-(amido)imides
US6433016B1 (en) 2001-01-12 2002-08-13 Vassil Stefanov Georgiev Drugs for treating viral infections
US6596771B2 (en) 2001-01-12 2003-07-22 Schering Corporation Drugs for treating viral infections
US20040087548A1 (en) * 2001-02-27 2004-05-06 Salvati Mark E. Fused cyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
ES2632313T3 (es) * 2003-06-20 2017-09-12 Siga Technologies Inc. Compuestos, composiciones y métodos para el tratamiento y la prevención de infecciones por ortopoxvirus y enfermedades asociadas

Also Published As

Publication number Publication date
WO2004112718A2 (en) 2004-12-29
EP1638938A4 (en) 2008-09-17
WO2004112718A3 (en) 2005-04-07
JP2011252019A (ja) 2011-12-15
PL1638938T3 (pl) 2017-10-31
AU2004249250B2 (en) 2011-09-01
CA2529761A1 (en) 2004-12-29
JP5657489B2 (ja) 2015-01-21
AU2004249250C1 (en) 2012-04-12
EP1638938B1 (en) 2017-04-12
JP2007521273A (ja) 2007-08-02
ES2632313T3 (es) 2017-09-12
FR22C1022I1 (fr) 2022-07-22
AU2004249250A1 (en) 2004-12-29
EP1638938A2 (en) 2006-03-29
DK1638938T3 (en) 2017-07-31
CA2529761C (en) 2013-08-13
NL301177I1 (nl) 2022-06-08
JP4884216B2 (ja) 2012-02-29
BE2022C521I2 (nl) 2024-04-23

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