FR2293943A1 - Procede pour la preparation simultanee a partir d'un produit de depart, d'un concentre de globuline a, d'un complexe de prothrombine et d'une solution de proteines du serum therapeutiquement utilisables - Google Patents

Procede pour la preparation simultanee a partir d'un produit de depart, d'un concentre de globuline a, d'un complexe de prothrombine et d'une solution de proteines du serum therapeutiquement utilisables

Info

Publication number
FR2293943A1
FR2293943A1 FR7536833A FR7536833A FR2293943A1 FR 2293943 A1 FR2293943 A1 FR 2293943A1 FR 7536833 A FR7536833 A FR 7536833A FR 7536833 A FR7536833 A FR 7536833A FR 2293943 A1 FR2293943 A1 FR 2293943A1
Authority
FR
France
Prior art keywords
therapically
globulin
useable
concentrate
protein solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7536833A
Other languages
English (en)
French (fr)
Other versions
FR2293943B1 (https=
Inventor
Wolfgang Stephan
Ronald Kotitschke
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biotest Serum Institut GmbH
Original Assignee
Biotest Serum Institut GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biotest Serum Institut GmbH filed Critical Biotest Serum Institut GmbH
Publication of FR2293943A1 publication Critical patent/FR2293943A1/fr
Application granted granted Critical
Publication of FR2293943B1 publication Critical patent/FR2293943B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6429—Thrombin (3.4.21.5)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21005—Thrombin (3.4.21.5)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/829—Blood
    • Y10S530/83—Plasma; serum

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
FR7536833A 1974-12-14 1975-12-02 Procede pour la preparation simultanee a partir d'un produit de depart, d'un concentre de globuline a, d'un complexe de prothrombine et d'une solution de proteines du serum therapeutiquement utilisables Granted FR2293943A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2459291A DE2459291C3 (de) 1974-12-14 1974-12-14 Verfahren zur Herstellung eines antihämophiles Globulin A enthaltenden Konzentrats neben einem Prothrombin- Komplex und einer Lösung von lagerstabilen Serumproteinen

Publications (2)

Publication Number Publication Date
FR2293943A1 true FR2293943A1 (fr) 1976-07-09
FR2293943B1 FR2293943B1 (https=) 1979-01-19

Family

ID=5933473

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7536833A Granted FR2293943A1 (fr) 1974-12-14 1975-12-02 Procede pour la preparation simultanee a partir d'un produit de depart, d'un concentre de globuline a, d'un complexe de prothrombine et d'une solution de proteines du serum therapeutiquement utilisables

Country Status (8)

Country Link
US (1) US4081431A (https=)
JP (1) JPS5182716A (https=)
AT (1) AT343277B (https=)
BE (1) BE836193A (https=)
DE (1) DE2459291C3 (https=)
FR (1) FR2293943A1 (https=)
GB (1) GB1519208A (https=)
NL (1) NL7514338A (https=)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2473886A1 (fr) * 1980-01-18 1981-07-24 Merieux Inst Perfectionnement aux procedes de concentration et de purification du facteur anti-hemophilique (facteur viii) et preparations de facteur viii concentre et purifie obtenues
EP0076870A1 (en) * 1981-10-12 1983-04-20 Armour Pharmaceutical Company Process for the preparation of highly purified antihemophilic factor
EP0111777A1 (de) * 1982-12-21 1984-06-27 Biotest-Serum-Institut GmbH Gerinnungsaktive Plasmaproteinlösung, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Störungen des Hämostasesystems
FR2573997A1 (fr) * 1984-12-03 1986-06-06 Commissariat Energie Atomique Support solide capable d'adsorber des lipoproteines et son utilisation pour la separation des lipoproteines de basse densite presentes dans un liquide tel que le plasma sanguin

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT350726B (de) * 1976-08-30 1979-06-11 Immuno Ag Verfahren zur herstellung einer blut- gerinnungsfoerdernden praeperation aus menschlichem blutplasma
DE2801123C2 (de) * 1977-01-26 1986-01-02 Armour Pharma GmbH & Co KG, 3440 Eschwege Verfahren zur Herstellung eines intravenös applizierbaren Serumeiweiß-Präparates
DE2902158A1 (de) * 1979-01-20 1980-07-31 Biotest Serum Institut Gmbh Verfahren zur herstellung von fibrinogen, einem die gerinnungsfaktoren ii, vii, ix und x enthaltenden prothrombinkomplex, antithrombin iii und einer loesung von lagerstabilen serumproteinen
US4228154A (en) * 1979-02-26 1980-10-14 Armour Pharmaceutical Company Purification of plasma albumin by ion exchange chromatography
US4210580A (en) * 1979-06-19 1980-07-01 David Amrani Process for separation and isolation of AHF and fibronectin from blood plasma
US4278594A (en) * 1979-06-19 1981-07-14 David Amrani Process for separation and isolation of AHF, von Willebrand's ristocetin cofactor (VWF:RCF) and fibronectin from blood plasma
US4391746A (en) * 1980-05-27 1983-07-05 Cutter Laboratories, Inc. Blood-coagulation-promoting products and methods of preparing them
US4361510A (en) * 1980-05-27 1982-11-30 Cutter Laboratories, Inc. Blood coagulation promoting product
US4364861A (en) * 1980-05-27 1982-12-21 Cutter Laboratories, Inc. Blood-coagulation-promoting products and methods of preparing them
US4404132A (en) * 1980-05-27 1983-09-13 Cutter Laboratories, Inc. Blood coagulation promoting product
DE3033932C2 (de) * 1980-09-10 1984-05-24 Biotest-Serum-Institut Gmbh, 6000 Frankfurt Verfahren zur Kaltsterilisation von Blutgerinnungsfaktor VIII enthaltenden Präparaten
DE3101752A1 (de) * 1981-01-21 1982-08-26 Behringwerke Ag, 3550 Marburg "verfahren zur reinigung der blutgerinnungsfaktoren ii, vii, ix und/oder x und danach hergestellte praeparationen"
US4473647A (en) * 1981-02-27 1984-09-25 Amf Inc. Tissue culture medium
EP0081482A1 (en) * 1981-06-18 1983-06-22 E. G. Birger Blombäck A process in purification and concentration of the factor viii complex
JPS6317899A (ja) * 1986-07-09 1988-01-25 Green Cross Corp:The ハプトグロビンの精製方法
US4725673A (en) * 1986-08-29 1988-02-16 Alpha Therapeutic Corporation Plasma fraction purification using silica resin bound to a ligand
DE3877529T2 (de) * 1987-10-23 1996-11-07 Centre Regional De Transfusion Herstellung von hoch-gereingtem menschlichen Faktor IX sowie anderem Plasmaproteinkonzentrat und dessen therapeutische Verwendung.
US4963265A (en) * 1988-05-06 1990-10-16 Applied Immunesciences, Inc. Plasma processing device with anaphylatoxin remover
WO1992015670A1 (en) * 1991-02-28 1992-09-17 Hyclone Laboratories, Inc. Blended bovine sera cellular growth media and their methods of production and use
DE69826531T2 (de) * 1998-06-23 2005-09-22 Shanbrom Technologies, LLC, Ojai Verfahren und vorrichtung zur herstellung von gereinigten plasmaproteinen
US8597471B2 (en) 2010-08-19 2013-12-03 Industrial Idea Partners, Inc. Heat driven concentrator with alternate condensers
AU2014262532B2 (en) 2013-05-09 2019-08-22 Advanced Neuroregenerative Therapies, Llc G-CSF for use in treating or preventing a disease associated with aging in a patient, for administration with a stem-cell containing composition and/or an electromagnetic signal

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3652530A (en) * 1967-08-28 1972-03-28 American Nat Red Cross Antihemophilic factor prepared from blood plasma using polyethylene glycol
US3916026A (en) * 1968-09-19 1975-10-28 Biotest Serum Institut Gmbh Method for the preparation of gamma-globulin suitable for intravenous use
US3682881A (en) * 1970-10-02 1972-08-08 Baxter Laboratories Inc Fractionation of plasma using glycine and polyethylene glycol
US3869436A (en) * 1971-06-01 1975-03-04 Statens Bakteriologiska Lab Method for fractionating plasma proteins using peg and ion-exchangers
US3920625A (en) * 1973-06-19 1975-11-18 Kabi Ab Isolation of coagulation factors from biological material using cross linked sulfated, sulfonated carbohydrates
US3973002A (en) * 1974-04-12 1976-08-03 E. R. Squibb & Sons, Inc. Antihemophilic factor

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2473886A1 (fr) * 1980-01-18 1981-07-24 Merieux Inst Perfectionnement aux procedes de concentration et de purification du facteur anti-hemophilique (facteur viii) et preparations de facteur viii concentre et purifie obtenues
EP0076870A1 (en) * 1981-10-12 1983-04-20 Armour Pharmaceutical Company Process for the preparation of highly purified antihemophilic factor
EP0111777A1 (de) * 1982-12-21 1984-06-27 Biotest-Serum-Institut GmbH Gerinnungsaktive Plasmaproteinlösung, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Störungen des Hämostasesystems
FR2573997A1 (fr) * 1984-12-03 1986-06-06 Commissariat Energie Atomique Support solide capable d'adsorber des lipoproteines et son utilisation pour la separation des lipoproteines de basse densite presentes dans un liquide tel que le plasma sanguin

Also Published As

Publication number Publication date
ATA939375A (de) 1977-09-15
NL7514338A (nl) 1976-06-16
DE2459291C3 (de) 1981-06-04
JPS5516487B2 (https=) 1980-05-02
DE2459291A1 (de) 1976-06-16
GB1519208A (en) 1978-07-26
US4081431A (en) 1978-03-28
DE2459291B2 (de) 1979-03-15
BE836193A (fr) 1976-04-01
FR2293943B1 (https=) 1979-01-19
AT343277B (de) 1978-05-26
JPS5182716A (en) 1976-07-20

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ST Notification of lapse