FR2276289A1 - Sels d'ammonium quaternaires - Google Patents

Sels d'ammonium quaternaires

Info

Publication number
FR2276289A1
FR2276289A1 FR7519766A FR7519766A FR2276289A1 FR 2276289 A1 FR2276289 A1 FR 2276289A1 FR 7519766 A FR7519766 A FR 7519766A FR 7519766 A FR7519766 A FR 7519766A FR 2276289 A1 FR2276289 A1 FR 2276289A1
Authority
FR
France
Prior art keywords
quaternary ammonium
ammonium salts
salts
quaternary
ammonium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7519766A
Other languages
English (en)
Other versions
FR2276289B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
INTER RESEARCH CORP
Original Assignee
INTER RESEARCH CORP
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by INTER RESEARCH CORP filed Critical INTER RESEARCH CORP
Publication of FR2276289A1 publication Critical patent/FR2276289A1/fr
Application granted granted Critical
Publication of FR2276289B1 publication Critical patent/FR2276289B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR7519766A 1974-06-24 1975-06-24 Sels d'ammonium quaternaires Granted FR2276289A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/482,513 US3998815A (en) 1974-06-24 1974-06-24 1-hydrocarbonoyloxymethyl-3-carbamoyl or 3-carboethoxy-pyridinium salts

Publications (2)

Publication Number Publication Date
FR2276289A1 true FR2276289A1 (fr) 1976-01-23
FR2276289B1 FR2276289B1 (fr) 1979-10-19

Family

ID=23916371

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7519766A Granted FR2276289A1 (fr) 1974-06-24 1975-06-24 Sels d'ammonium quaternaires

Country Status (6)

Country Link
US (2) US3998815A (fr)
AU (1) AU8241275A (fr)
CA (1) CA1045628A (fr)
DE (1) DE2527993A1 (fr)
FR (1) FR2276289A1 (fr)
GB (1) GB1471828A (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2422624A1 (fr) * 1977-12-16 1979-11-09 Inter Research Corp Nouveaux agents anticholinergiques doues d'activite antisecretoire, leur procede de preparation et leurs utilisations
FR2427600A1 (fr) * 1978-04-17 1979-12-28 Kyowa Hakko Kogyo Kk
WO1986001507A1 (fr) * 1984-08-23 1986-03-13 Sandoz Ag Sels cyclimmoniques

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3998815A (en) * 1974-06-24 1976-12-21 Interx Research Corporation 1-hydrocarbonoyloxymethyl-3-carbamoyl or 3-carboethoxy-pyridinium salts
US4171452A (en) * 1975-11-14 1979-10-16 Interx Research Corporation Antibacterially active N-chloroamino ester derivatives of alkyl carboxylates
JPS52122316A (en) * 1976-04-07 1977-10-14 Interx Research Corp New transitional quarternary ammonium salt compound
JPS5935599B2 (ja) * 1980-12-25 1984-08-29 株式会社 シノテスト研究所 コリンエステラ−ゼ活性測定法
HU186656B (en) * 1982-12-28 1985-09-30 Richter Gedeon Vegyeszet Process for producing new benzhydryl-piperazine derivatives, acid additionak salts and pharmaceutical compositions containing them
DE3443678A1 (de) * 1984-11-30 1986-06-05 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von 4-acyloxy-3-oxo-buttersaeureestern
US5258388A (en) * 1986-03-17 1993-11-02 University Of Florida Anticholinergic compounds, compositions and methods of treatment
CA1328106C (fr) * 1986-03-17 1994-03-29 Nicholas S. Bodor Composes anticholinergiques, compositions pharmaceutiques et methode du traitement
US5223528A (en) * 1986-03-17 1993-06-29 University Of Florida Anticholinergic compounds, composititons and methods of treatment
US5886162A (en) * 1989-11-03 1999-03-23 Research Foundation Of State University Of New York Lipophilic diakylaminomethylene prodrug derivatives for the inhibition of replication of viruses
US5849761A (en) * 1995-09-12 1998-12-15 Regents Of The University Of California Peripherally active anti-hyperalgesic opiates
US6573282B1 (en) 1995-09-12 2003-06-03 Adolor Corporation Peripherally active anti-hyperalgesic opiates
CN1129429C (zh) * 1996-05-20 2003-12-03 G·D·瑟尔公司 钾、钠和三羟甲基氨基甲烷噁丙嗪盐药物配方
CA2281875A1 (fr) 1997-03-31 1998-10-08 Takeda Chemical Industries, Ltd. Composes de type azole, leur production et leur utilisation
WO1999033846A2 (fr) * 1997-12-31 1999-07-08 The University Of Kansas Remedes contenant des precurseurs hydrosolubles d'amines secondaires et tertiaires, et leurs procedes d'obtention
IE20070597A1 (en) * 2007-08-21 2009-04-01 Univ Dublin City Biodegradable solvents for the chemical industry: task specific ionic liquids
JP5732453B2 (ja) 2009-06-25 2015-06-10 アルカーメス ファーマ アイルランド リミテッド Ｎｈ酸性化合物のプロドラッグ
US8431576B2 (en) 2009-06-25 2013-04-30 Alkermes Pharma Ireland Limited Heterocyclic compounds for the treatment of neurological and psychological disorders
WO2011084846A1 (fr) * 2010-01-07 2011-07-14 Alkermes, Inc. Promédicaments contenant des sels d'ammonium quaternaire
US8592427B2 (en) 2010-06-24 2013-11-26 Alkermes Pharma Ireland Limited Prodrugs of NH-acidic compounds: ester, carbonate, carbamate and phosphonate derivatives
IL296695A (en) 2011-03-18 2022-11-01 Alkermes Pharma Ireland Ltd Pharmaceutical preparations containing sorbitan esters
CA2858787C (fr) 2011-12-15 2017-11-21 Alkermes Pharma Ireland Limited Promedicaments de composes amines tertiaires
JP6333802B2 (ja) 2012-03-19 2018-05-30 アルカームス ファーマ アイルランド リミテッド ベンジルアルコールを含む医薬組成物
CA2867123C (fr) 2012-03-19 2021-02-16 Alkermes Pharma Ireland Limited Compositions pharmaceutiques renfermant des agents antipsychotiques non hydrosolubles et des esters glycerol
WO2013142198A1 (fr) 2012-03-19 2013-09-26 Alkermes Pharma Ireland Limited Compositions pharmaceutiques comprenant des esters d'acides gras
NZ730571A (en) 2012-09-19 2018-12-21 Alkermes Pharma Ireland Ltd Pharmaceutical compositions having improved storage stability
EP2903979B1 (fr) * 2012-10-04 2020-08-19 Inhibikase Therapeutics, Inc. Nouveaux composés, leur préparation et leurs utilisations
EP3119399A4 (fr) 2014-03-20 2017-09-27 Alkermes Pharma Ireland Limited Formulations d'aripiprazole présentant des vitesses d'injection plus élevées
CN105315170B (zh) * 2014-08-01 2017-08-25 四川大学华西医院 二甲基苯铵类长链化合物、制备、自组装结构及用途
CN110092731B (zh) * 2018-01-31 2022-03-04 四川大学华西医院 长链胺取代的二甲基苯铵类化合物、制备、自组装结构及用途
US11273158B2 (en) 2018-03-05 2022-03-15 Alkermes Pharma Ireland Limited Aripiprazole dosing strategy
CN113396139A (zh) * 2020-01-13 2021-09-14 易天奇 基于苯环超分子相互作用的芳基酰胺类化合物、自组装形态及用途
CN115215759B (zh) * 2021-04-19 2023-10-20 四川大学华西医院 一种兼具长效局部麻醉和选择性局部麻醉作用的酰胺类季铵盐衍生物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3396127A (en) * 1964-05-22 1968-08-06 Eastman Kodak Co Photographic hardeners
US3998815A (en) * 1974-06-24 1976-12-21 Interx Research Corporation 1-hydrocarbonoyloxymethyl-3-carbamoyl or 3-carboethoxy-pyridinium salts
US3989711A (en) * 1975-09-22 1976-11-02 Interx Research Corporation Soft quaternary surface active agents exhibiting antibacterial activity

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2422624A1 (fr) * 1977-12-16 1979-11-09 Inter Research Corp Nouveaux agents anticholinergiques doues d'activite antisecretoire, leur procede de preparation et leurs utilisations
FR2427600A1 (fr) * 1978-04-17 1979-12-28 Kyowa Hakko Kogyo Kk
WO1986001507A1 (fr) * 1984-08-23 1986-03-13 Sandoz Ag Sels cyclimmoniques

Also Published As

Publication number Publication date
DE2527993C2 (fr) 1988-08-11
GB1471828A (en) 1977-04-27
DE2527993A1 (de) 1976-01-15
US3998815A (en) 1976-12-21
US4160099A (en) 1979-07-03
FR2276289B1 (fr) 1979-10-19
CA1045628A (fr) 1979-01-02
AU8241275A (en) 1977-01-06

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Legal Events

Date Code Title Description
ST Notification of lapse