FR2258186A1 - 10-((4-hydroxyethylpiperidino)alkyl)-phenothiazines - with antiemetic activity - Google Patents

10-((4-hydroxyethylpiperidino)alkyl)-phenothiazines - with antiemetic activity

Info

Publication number
FR2258186A1
FR2258186A1 FR7402101A FR7402101A FR2258186A1 FR 2258186 A1 FR2258186 A1 FR 2258186A1 FR 7402101 A FR7402101 A FR 7402101A FR 7402101 A FR7402101 A FR 7402101A FR 2258186 A1 FR2258186 A1 FR 2258186A1
Authority
FR
France
Prior art keywords
alkyl
hydroxyethylpiperidino
phenothiazines
antiemetic activity
antiemetic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7402101A
Other languages
English (en)
French (fr)
Other versions
FR2258186B1 (enExample
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc Industries SA
Original Assignee
Rhone Poulenc Industries SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Industries SA filed Critical Rhone Poulenc Industries SA
Priority to FR7402101A priority Critical patent/FR2258186A1/fr
Priority to AR257380A priority patent/AR205635A1/es
Priority to AR260778A priority patent/AR207789A1/es
Priority to NL7500421.A priority patent/NL165739C/xx
Priority to HURO818A priority patent/HU168855B/hu
Priority to IL7546484A priority patent/IL46484A/en
Priority to JP839775A priority patent/JPS541313B2/ja
Priority to AU77487/75A priority patent/AU470810B2/en
Priority to DK17275*#A priority patent/DK17275A/da
Priority to CA218,368A priority patent/CA1021337A/en
Priority to BE152581A priority patent/BE824626A/xx
Priority to LU71688*A priority patent/LU71688A1/xx
Priority to GB259975A priority patent/GB1460427A/en
Priority to CH1069477A priority patent/CH602720A5/xx
Priority to SE7500642A priority patent/SE414028B/xx
Priority to NO750182A priority patent/NO750182L/no
Priority to CS75418A priority patent/CS187458B2/cs
Priority to ZA00750395A priority patent/ZA75395B/xx
Priority to SU7502101069A priority patent/SU577994A3/ru
Priority to IE109/75A priority patent/IE40364B1/xx
Priority to US05/542,799 priority patent/US3961055A/en
Priority to CH70975A priority patent/CH602718A5/xx
Priority to DE2502504A priority patent/DE2502504C3/de
Priority to FI750160A priority patent/FI57948C/fi
Priority to ES434026A priority patent/ES434026A1/es
Priority to AT46475A priority patent/AT338816B/de
Priority to ES439072A priority patent/ES439072A1/es
Publication of FR2258186A1 publication Critical patent/FR2258186A1/fr
Priority to CS773616A priority patent/CS187499B2/cs
Priority to SE7709432A priority patent/SE414029B/xx
Application granted granted Critical
Publication of FR2258186B1 publication Critical patent/FR2258186B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
    • C07D279/18—[b, e]-condensed with two six-membered rings
    • C07D279/22—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom
    • C07D279/24—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom with hydrocarbon radicals, substituted by amino radicals, attached to the ring nitrogen atom
    • C07D279/28—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom with hydrocarbon radicals, substituted by amino radicals, attached to the ring nitrogen atom with other substituents attached to the ring system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR7402101A 1974-01-22 1974-01-22 10-((4-hydroxyethylpiperidino)alkyl)-phenothiazines - with antiemetic activity Granted FR2258186A1 (en)

Priority Applications (29)

Application Number Priority Date Filing Date Title
FR7402101A FR2258186A1 (en) 1974-01-22 1974-01-22 10-((4-hydroxyethylpiperidino)alkyl)-phenothiazines - with antiemetic activity
AR257380A AR205635A1 (es) 1974-01-22 1975-01-01 Procedimiento para preparar nuevos derivados de la (((hidroxi-2 etil)-4-piperidino) -3 propil) -10 fenotiazina
AR260778A AR207789A1 (es) 1974-01-22 1975-01-01 Procedimiento para preparar nuevos esteres derivados de 2-hidroxi-2-dimetilsulfamoil-6-(((hidroxi-2-etil)-4-pipedidino)-3-propil)-10-fenotiazina
NL7500421.A NL165739C (nl) 1974-01-22 1975-01-14 Werkwijze ter bereiding van farmaceutische preparaten met antiemetische werking, die fenothiazinederivaten bevatten, verkregen gevormde preparaten en werkwijze ter bereiding van de nieuwe fenothiazinederivaten.
HURO818A HU168855B (enExample) 1974-01-22 1975-01-20
SU7502101069A SU577994A3 (ru) 1974-01-22 1975-01-21 Способ получени производных фенотиазина или их солей
AU77487/75A AU470810B2 (en) 1974-01-22 1975-01-21 New phenothiazine derivatives
DK17275*#A DK17275A (enExample) 1974-01-22 1975-01-21
CA218,368A CA1021337A (en) 1974-01-22 1975-01-21 Phenothiazine derivatives, their preparation and compositions
BE152581A BE824626A (fr) 1974-01-22 1975-01-21 Nouveaux derives de la phenothiazine, leur preparation et les compositions qui les contiennent
LU71688*A LU71688A1 (enExample) 1974-01-22 1975-01-21
GB259975A GB1460427A (en) 1974-01-22 1975-01-21 Phenothiazine derivatives
CH1069477A CH602720A5 (enExample) 1974-01-22 1975-01-21
SE7500642A SE414028B (sv) 1974-01-22 1975-01-21 Forfarande for framstellning av terapeutisk verksamma fentiazinderivat
IL7546484A IL46484A (en) 1974-01-22 1975-01-21 2-hydroxy-10-(3-(4-(2-hydroxyethyl)-piperidino)propyl)-phenothiazine derivatives processes for the preparation thereof and pharmaceutical compositions containing the same
CS75418A CS187458B2 (en) 1974-01-22 1975-01-21 Process for preparing new derivatives of phenothiazine
ZA00750395A ZA75395B (en) 1974-01-22 1975-01-21 New phenothiazine derivatives
JP839775A JPS541313B2 (enExample) 1974-01-22 1975-01-21
IE109/75A IE40364B1 (en) 1974-01-22 1975-01-21 New phenothiazine derivatives
US05/542,799 US3961055A (en) 1974-01-22 1975-01-21 Hydroxy and ether containing phenothiazine derivatives
CH70975A CH602718A5 (enExample) 1974-01-22 1975-01-21
NO750182A NO750182L (enExample) 1974-01-22 1975-01-21
DE2502504A DE2502504C3 (de) 1974-01-22 1975-01-22 Phenothiazinderivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen
FI750160A FI57948C (fi) 1974-01-22 1975-01-22 Foerfarande foer framstaellning av antiemetiska 10-(3-(4-(2-hydroxietyl)piperidino)propyl)fenotiaziner
ES434026A ES434026A1 (es) 1974-01-22 1975-01-22 Procedimiento para preparar derivados de la fenotiazina.
AT46475A AT338816B (de) 1974-01-22 1975-01-22 Verfahren zur herstellung von neuen phenthiazinderivaten und von ihren saureadditionssalzen
ES439072A ES439072A1 (es) 1974-01-22 1975-07-02 Procedimiento para preparar derivados de la fenotiazina.
CS773616A CS187499B2 (en) 1974-01-22 1977-06-01 Process for preparing new derivatives of phenothiazine
SE7709432A SE414029B (sv) 1974-01-22 1977-08-22 Forfarande for framstellning av terapeutiskt aktiva fentiazinderivat

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7402101A FR2258186A1 (en) 1974-01-22 1974-01-22 10-((4-hydroxyethylpiperidino)alkyl)-phenothiazines - with antiemetic activity

Publications (2)

Publication Number Publication Date
FR2258186A1 true FR2258186A1 (en) 1975-08-18
FR2258186B1 FR2258186B1 (enExample) 1978-03-24

Family

ID=9133818

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7402101A Granted FR2258186A1 (en) 1974-01-22 1974-01-22 10-((4-hydroxyethylpiperidino)alkyl)-phenothiazines - with antiemetic activity

Country Status (3)

Country Link
BE (1) BE824626A (enExample)
FR (1) FR2258186A1 (enExample)
ZA (1) ZA75395B (enExample)

Also Published As

Publication number Publication date
BE824626A (fr) 1975-07-22
ZA75395B (en) 1976-01-28
FR2258186B1 (enExample) 1978-03-24

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Legal Events

Date Code Title Description
ST Notification of lapse