FR2250764A1 - - Google Patents

Info

Publication number
FR2250764A1
FR2250764A1 FR7437148A FR7437148A FR2250764A1 FR 2250764 A1 FR2250764 A1 FR 2250764A1 FR 7437148 A FR7437148 A FR 7437148A FR 7437148 A FR7437148 A FR 7437148A FR 2250764 A1 FR2250764 A1 FR 2250764A1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7437148A
Other languages
French (fr)
Other versions
FR2250764B1 (enExample
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of FR2250764A1 publication Critical patent/FR2250764A1/fr
Application granted granted Critical
Publication of FR2250764B1 publication Critical patent/FR2250764B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
FR7437148A 1973-11-12 1974-11-08 Expired FR2250764B1 (enExample)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US415186A US3887545A (en) 1973-11-12 1973-11-12 Synthesis of 1{60 -hydroxylated cholesterol derivatives

Publications (2)

Publication Number Publication Date
FR2250764A1 true FR2250764A1 (enExample) 1975-06-06
FR2250764B1 FR2250764B1 (enExample) 1979-08-03

Family

ID=23644712

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7437148A Expired FR2250764B1 (enExample) 1973-11-12 1974-11-08

Country Status (9)

Country Link
US (1) US3887545A (enExample)
JP (1) JPS5438098B2 (enExample)
AT (1) AT342793B (enExample)
BE (1) BE821983A (enExample)
CH (1) CH599247A5 (enExample)
DE (1) DE2453648C3 (enExample)
FR (1) FR2250764B1 (enExample)
GB (1) GB1443680A (enExample)
NL (1) NL7414675A (enExample)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3993675A (en) * 1975-02-24 1976-11-23 Hoffmann-La Roche Inc. Process for the preparation of 1α,25-dihydroxycholecalciferol
US4264512A (en) * 1975-09-29 1981-04-28 The Regents Of The University Of California 3-Deoxy-1α-hydroxy- and 3-deoxy-1α,25-dihydroxycholecalciferol and processes for the preparation thereof
JPS603045B2 (ja) * 1976-04-19 1985-01-25 中外製薬株式会社 １α―ヒドロキシビタミンＤ類軟カプセルの製造方法
US4098801A (en) * 1977-01-26 1978-07-04 Hoffmann-La Roche Inc. Synthesis of 1α-hydroxylated derivatives of cholesterol
US4260549A (en) * 1979-05-21 1981-04-07 Wisconsin Alumni Research Foundation Process for preparing 1α-hydroxylated compounds
LU80545A1 (de) * 1978-11-17 1980-06-05 Hoffmann La Roche Verfahren zur herstellung von 1a,3s-dihydroxy->5-steroiden
US4217279A (en) * 1978-12-18 1980-08-12 Kaiser Emil T Synthesis of steroids
US5952317A (en) * 1995-09-21 1999-09-14 Wisconsin Alumni Research Foundation Calcitriol derivatives and their uses
US5976784A (en) * 1996-09-20 1999-11-02 Wisconsin Alumni Research Foundation Calcitriol derivatives and their uses
DE69721304T2 (de) 1996-12-20 2004-03-04 Novo Nordisk A/S Verbindungen zur Regulierung der Meiose
MXPA01011070A (es) * 1999-04-30 2003-06-30 Arch Dev Corp Derivados de esteroides.
CN1498222A (zh) * 2001-02-08 2004-05-19 芝加哥大学 类固醇衍生物
US20070197484A1 (en) * 2001-05-03 2007-08-23 Ching Song Method of treating disorder related to high cholesterol concentration
US7078396B2 (en) * 2001-05-03 2006-07-18 Arch Development Corporation Method of treating disorder related to high cholesterol concentration
EP1494533A2 (en) * 2002-04-12 2005-01-12 The University of Chicago Farnesoid x-activated receptor agonists
CA2495882A1 (en) * 2002-08-29 2004-03-11 The Regents Of The University Of California Agents and methods for enhancing bone formation
US9532994B2 (en) * 2003-08-29 2017-01-03 The Regents Of The University Of California Agents and methods for enhancing bone formation by oxysterols in combination with bone morphogenic proteins
US20070032464A1 (en) * 2004-10-08 2007-02-08 Shutsung Liao Methods of treating cancers
CN101163882B (zh) * 2005-04-23 2011-08-10 艾克塞蒂克马克有限公司 轴向活塞机及其制造方法
JP2009512422A (ja) * 2005-09-02 2009-03-26 ザ リージェンツ オブ ザ ユニヴァーシティー オブ カリフォルニア 骨形成及び抗脂肪細胞形成オキシステロール類
EP1993558B1 (en) * 2006-02-27 2014-07-30 The Regents of The University of California Oxysterol compounds and the hedgehog pathway
WO2008011071A2 (en) * 2006-07-19 2008-01-24 The Regents Of The University Of California Interactions of hedgehog and liver x receptor signaling pathways
AU2007339325A1 (en) 2006-12-19 2008-07-10 The Regents Of The University Of California Inhibition of PPAR gamma expression by specific osteogenic oxysterols
US20100112030A1 (en) * 2007-03-16 2010-05-06 The Regents Of The University Of California Role of hedgehog signaling in atherosclerosis and cardiovascular disease
WO2009073186A1 (en) * 2007-12-03 2009-06-11 The Regents Of The University Of California Oxsterols for activation of hedgehog signaling, osteoinduction, antiadipogenesis, and wnt signaling
US8829213B2 (en) * 2009-07-29 2014-09-09 The University Of Chicago Liver X receptor agonists
CN104395331B (zh) 2012-05-07 2016-11-02 加利福尼亚大学董事会 诱导骨生成和hedgehog 信号传导且抑制脂肪形成的氧固醇类似物氧固醇化合物133
EP2991652A4 (en) 2013-05-02 2016-12-07 Univ California BONE-LAYERED BONE-RELATED OSTEOGENIC OXYSTEROL AGENTS
CN114315947B (zh) * 2021-11-17 2023-10-03 王涛 一种由22-甾醇作为原料合成胆固醇和25-羟基胆固醇的新方法
CN116514893B (zh) * 2022-01-28 2025-12-05 珂阑(上海)医药科技有限公司 甾类化合物、其制备方法和应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3080937A (en) * 1960-11-07 1963-03-12 Garbell Res Foundation Combined acoustic wall and exhaust gas deflector in operation of jet engines
US3741996A (en) * 1971-12-02 1973-06-26 Wisconsin Alumni Res Found 1{60 -hydroxycholecalciferol

Also Published As

Publication number Publication date
AT342793B (de) 1978-04-25
DE2453648B2 (de) 1980-06-26
NL7414675A (nl) 1975-05-14
BE821983A (fr) 1975-05-09
GB1443680A (en) 1976-07-21
JPS5077360A (enExample) 1975-06-24
FR2250764B1 (enExample) 1979-08-03
DE2453648A1 (de) 1975-05-15
JPS5438098B2 (enExample) 1979-11-19
ATA899274A (de) 1977-08-15
CH599247A5 (enExample) 1978-05-31
US3887545A (en) 1975-06-03
DE2453648C3 (de) 1981-08-06

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Legal Events

Date Code Title Description
ST Notification of lapse