FR2248841B1 - - Google Patents

Info

Publication number
FR2248841B1
FR2248841B1 FR7435550A FR7435550A FR2248841B1 FR 2248841 B1 FR2248841 B1 FR 2248841B1 FR 7435550 A FR7435550 A FR 7435550A FR 7435550 A FR7435550 A FR 7435550A FR 2248841 B1 FR2248841 B1 FR 2248841B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7435550A
Other languages
French (fr)
Other versions
FR2248841A1 (enExample
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP12126073A external-priority patent/JPS5732065B2/ja
Priority claimed from JP12175773A external-priority patent/JPS5724786B2/ja
Application filed by Individual filed Critical Individual
Publication of FR2248841A1 publication Critical patent/FR2248841A1/fr
Application granted granted Critical
Publication of FR2248841B1 publication Critical patent/FR2248841B1/fr
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87Benzo [c] furans; Hydrogenated benzo [c] furans
    • C07D307/89Benzo [c] furans; Hydrogenated benzo [c] furans with two oxygen atoms directly attached in positions 1 and 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR7435550A 1973-10-30 1974-10-23 Expired FR2248841B1 (enExample)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP12126073A JPS5732065B2 (enExample) 1973-10-30 1973-10-30
JP12175773A JPS5724786B2 (enExample) 1973-10-31 1973-10-31

Publications (2)

Publication Number Publication Date
FR2248841A1 FR2248841A1 (enExample) 1975-05-23
FR2248841B1 true FR2248841B1 (enExample) 1978-07-28

Family

ID=26458679

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7435550A Expired FR2248841B1 (enExample) 1973-10-30 1974-10-23

Country Status (20)

Country Link
US (1) US3963716A (enExample)
AR (1) AR205004A1 (enExample)
CA (1) CA1029377A (enExample)
CH (2) CH610892A5 (enExample)
DD (1) DD119231A5 (enExample)
DE (1) DE2451417C3 (enExample)
DK (1) DK134345B (enExample)
ES (1) ES431454A1 (enExample)
FI (1) FI59402C (enExample)
FR (1) FR2248841B1 (enExample)
GB (1) GB1459606A (enExample)
HU (1) HU168797B (enExample)
IE (1) IE39831B1 (enExample)
IL (1) IL45675A (enExample)
IN (1) IN139552B (enExample)
LU (1) LU71191A1 (enExample)
NL (1) NL7414186A (enExample)
PH (1) PH10519A (enExample)
SE (1) SE412389B (enExample)
YU (1) YU289774A (enExample)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4120960A (en) * 1973-10-31 1978-10-17 The Boots Company Limited Therapeutic agents
NL7702763A (nl) * 1976-03-18 1977-09-20 Takio Shimamoto En Masayuki Is Werkwijze voor de bereiding van thromboxaan- -antagonisten en van preparaten die deze stof- fen bevatten.
IE47592B1 (en) * 1977-12-29 1984-05-02 Ici Ltd Enzyme inhibitory phthalazin-4-ylacetic acid derivatives, pharmaceutical compositions thereof,and process for their manufacture
US4293553A (en) * 1978-08-11 1981-10-06 Masayuki Ishikawa 1-Phthalazone derivatives, and use thereof
US4464532A (en) * 1979-07-31 1984-08-07 Nippon Kayaku Kabushiki Kaisha Intermediates of 7-alkoxycarbonyl-6,8-dimethyl-4-hydroxymethyl-1-phthalazone
JPS5668609A (en) * 1979-11-07 1981-06-09 Nippon Kayaku Co Ltd Phthalazinol preparation
JPS58116471A (ja) * 1981-12-29 1983-07-11 Nippon Kayaku Co Ltd 4−ヒドロキシメチル−1−フタラゾンエステル誘導体およびその塩
GB2127805A (en) * 1982-09-13 1984-04-18 Showa Denko Kk Phthalazones
US4861778A (en) * 1986-06-16 1989-08-29 Research Corporation 2,3-dihydrophthalazine-1,4-diones
DE68920798T2 (de) * 1988-08-19 1995-05-18 Warner Lambert Co Substituierte Dihydroisochinolinone und verwandte Verbindungen als Verstärker der letalen Effekte von Bestrahlung und bestimmten Chemotherapeutika; ausgewählte Verbindungen, Analoga und Verfahren.
US5177075A (en) * 1988-08-19 1993-01-05 Warner-Lambert Company Substituted dihydroisoquinolinones and related compounds as potentiators of the lethal effects of radiation and certain chemotherapeutic agents; selected compounds, analogs and process
DE4333761A1 (de) * 1993-10-04 1995-04-06 Luitpold Pharma Gmbh Heterocyclische Carbamate, Verfahren zu ihrer Herstellung und Arzneimittel
RU2169139C1 (ru) * 2000-08-02 2001-06-20 Закрытое акционерное общество "Центр современной медицины "Медикор" Способ получения щелочных и щелочноземельных солей 5-амино-2,3-дигидро-1,4-фталазиндиона
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
MX354786B (es) 2007-06-04 2018-03-21 Synergy Pharmaceuticals Inc Agonistas de guanilato ciclasa utiles para el tratamiento de trastornos gastrointestinales, inflamacion, cancer y otros trastornos.
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
CA2726917C (en) 2008-06-04 2018-06-26 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
EP2321341B1 (en) 2008-07-16 2017-02-22 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
BR112012011237A2 (pt) 2009-11-13 2019-09-24 Univ Tokyo agente terapêutico e profilático para diabetes
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
EA201391254A1 (ru) 2011-03-01 2014-02-28 Синерджи Фармасьютикалз Инк. Способ получения агонистов гуанилатциклазы c
JP6499591B2 (ja) 2013-02-25 2019-04-10 シナジー ファーマシューティカルズ インコーポレイテッド 結腸洗浄において用いるためのグアニル酸シクラーゼ受容体アゴニスト
WO2014151200A2 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Compositions useful for the treatment of gastrointestinal disorders
JP2016514671A (ja) 2013-03-15 2016-05-23 シナジー ファーマシューティカルズ インコーポレイテッド グアニル酸シクラーゼのアゴニストおよびその使用
CN105764916B (zh) 2013-06-05 2021-05-18 博士医疗爱尔兰有限公司 鸟苷酸环化酶c的超纯激动剂、制备和使用所述激动剂的方法
EP3492106B1 (en) 2013-08-09 2021-02-17 Ardelyx, Inc. Compounds and methods for inhibiting phosphate transport
EP3972599B1 (en) 2019-05-21 2025-10-22 Ardelyx, Inc. Combination for lowering serum phosphate in a patient

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5116430B2 (enExample) * 1971-08-05 1976-05-24
US3870792A (en) * 1972-07-24 1975-03-11 Michiro Inoue Certain dihydrophthalizines for treating hemorrhage and thrombosis

Also Published As

Publication number Publication date
FI315774A7 (enExample) 1975-05-01
US3963716A (en) 1976-06-15
FR2248841A1 (enExample) 1975-05-23
DE2451417B2 (de) 1980-05-14
DK134345C (enExample) 1977-03-21
CH611282A5 (enExample) 1979-05-31
HU168797B (enExample) 1976-07-28
SE7413530L (enExample) 1975-05-02
PH10519A (en) 1977-05-26
IL45675A (en) 1978-10-31
LU71191A1 (enExample) 1975-04-17
IE39831L (en) 1975-04-30
FI59402C (fi) 1981-08-10
FI59402B (fi) 1981-04-30
YU289774A (en) 1983-01-21
IN139552B (enExample) 1976-07-03
ES431454A1 (es) 1976-10-16
AR205004A1 (es) 1976-03-31
DD119231A5 (enExample) 1976-04-12
IE39831B1 (en) 1979-01-03
DE2451417C3 (de) 1981-01-29
CA1029377A (en) 1978-04-11
CH610892A5 (enExample) 1979-05-15
GB1459606A (en) 1976-12-22
DK134345B (da) 1976-10-25
SE412389B (sv) 1980-03-03
DE2451417A1 (de) 1975-05-07
NL7414186A (nl) 1975-05-02
AU7295474A (en) 1976-03-11
DK561874A (enExample) 1975-07-07
IL45675A0 (en) 1974-11-29

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Legal Events

Date Code Title Description
ST Notification of lapse