CA1029377A - 1-phthalazone derivate, a process for its preparation and pharmaceutical compositions containing it - Google Patents
1-phthalazone derivate, a process for its preparation and pharmaceutical compositions containing itInfo
- Publication number
- CA1029377A CA1029377A CA212,163A CA212163A CA1029377A CA 1029377 A CA1029377 A CA 1029377A CA 212163 A CA212163 A CA 212163A CA 1029377 A CA1029377 A CA 1029377A
- Authority
- CA
- Canada
- Prior art keywords
- phthalazone
- derivate
- preparation
- pharmaceutical compositions
- compositions containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
- C07D307/89—Benzo [c] furans; Hydrogenated benzo [c] furans with two oxygen atoms directly attached in positions 1 and 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP12126073A JPS5732065B2 (enExample) | 1973-10-30 | 1973-10-30 | |
| JP12175773A JPS5724786B2 (enExample) | 1973-10-31 | 1973-10-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1029377A true CA1029377A (en) | 1978-04-11 |
Family
ID=26458679
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA212,163A Expired CA1029377A (en) | 1973-10-30 | 1974-10-24 | 1-phthalazone derivate, a process for its preparation and pharmaceutical compositions containing it |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US3963716A (enExample) |
| AR (1) | AR205004A1 (enExample) |
| CA (1) | CA1029377A (enExample) |
| CH (2) | CH610892A5 (enExample) |
| DD (1) | DD119231A5 (enExample) |
| DE (1) | DE2451417C3 (enExample) |
| DK (1) | DK134345B (enExample) |
| ES (1) | ES431454A1 (enExample) |
| FI (1) | FI59402C (enExample) |
| FR (1) | FR2248841B1 (enExample) |
| GB (1) | GB1459606A (enExample) |
| HU (1) | HU168797B (enExample) |
| IE (1) | IE39831B1 (enExample) |
| IL (1) | IL45675A (enExample) |
| IN (1) | IN139552B (enExample) |
| LU (1) | LU71191A1 (enExample) |
| NL (1) | NL7414186A (enExample) |
| PH (1) | PH10519A (enExample) |
| SE (1) | SE412389B (enExample) |
| YU (1) | YU289774A (enExample) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4120960A (en) * | 1973-10-31 | 1978-10-17 | The Boots Company Limited | Therapeutic agents |
| NL7702763A (nl) * | 1976-03-18 | 1977-09-20 | Takio Shimamoto En Masayuki Is | Werkwijze voor de bereiding van thromboxaan- -antagonisten en van preparaten die deze stof- fen bevatten. |
| IE47592B1 (en) * | 1977-12-29 | 1984-05-02 | Ici Ltd | Enzyme inhibitory phthalazin-4-ylacetic acid derivatives, pharmaceutical compositions thereof,and process for their manufacture |
| US4293553A (en) * | 1978-08-11 | 1981-10-06 | Masayuki Ishikawa | 1-Phthalazone derivatives, and use thereof |
| US4464532A (en) * | 1979-07-31 | 1984-08-07 | Nippon Kayaku Kabushiki Kaisha | Intermediates of 7-alkoxycarbonyl-6,8-dimethyl-4-hydroxymethyl-1-phthalazone |
| JPS5668609A (en) * | 1979-11-07 | 1981-06-09 | Nippon Kayaku Co Ltd | Phthalazinol preparation |
| JPS58116471A (ja) * | 1981-12-29 | 1983-07-11 | Nippon Kayaku Co Ltd | ４−ヒドロキシメチル−１−フタラゾンエステル誘導体およびその塩 |
| GB2127805A (en) * | 1982-09-13 | 1984-04-18 | Showa Denko Kk | Phthalazones |
| US4861778A (en) * | 1986-06-16 | 1989-08-29 | Research Corporation | 2,3-dihydrophthalazine-1,4-diones |
| JP2786896B2 (ja) * | 1988-08-19 | 1998-08-13 | ワーナー―ランバート・コンパニー | 置換されたジヒドロイソキノリノンおよび関連化合物 |
| US5177075A (en) * | 1988-08-19 | 1993-01-05 | Warner-Lambert Company | Substituted dihydroisoquinolinones and related compounds as potentiators of the lethal effects of radiation and certain chemotherapeutic agents; selected compounds, analogs and process |
| DE4345266C2 (de) * | 1993-10-04 | 1996-12-19 | Luitpold Pharma Gmbh | Heterocyclische Carbamate, Verfahren zu ihrer Herstellung und Arzneimittel |
| RU2169139C1 (ru) * | 2000-08-02 | 2001-06-20 | Закрытое акционерное общество "Центр современной медицины "Медикор" | Способ получения щелочных и щелочноземельных солей 5-амино-2,3-дигидро-1,4-фталазиндиона |
| US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
| US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
| WO2008151257A2 (en) | 2007-06-04 | 2008-12-11 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| ES2627848T3 (es) | 2008-06-04 | 2017-07-31 | Synergy Pharmaceuticals Inc. | Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos |
| ES2624828T3 (es) | 2008-07-16 | 2017-07-17 | Synergy Pharmaceuticals Inc. | Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros |
| KR101701943B1 (ko) | 2009-11-13 | 2017-02-02 | 도레이 카부시키가이샤 | 당뇨병의 치료 또는 예방약 |
| US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
| MX357121B (es) | 2011-03-01 | 2018-06-27 | Synergy Pharmaceuticals Inc Star | Proceso de preparacion de agonistas c de guanilato ciclasa. |
| EP2958577A2 (en) | 2013-02-25 | 2015-12-30 | Synergy Pharmaceuticals Inc. | Guanylate cyclase receptor agonists for use in colonic cleansing |
| US9708367B2 (en) | 2013-03-15 | 2017-07-18 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase and their uses |
| EP2968439A2 (en) | 2013-03-15 | 2016-01-20 | Synergy Pharmaceuticals Inc. | Compositions useful for the treatment of gastrointestinal disorders |
| PL3004138T3 (pl) | 2013-06-05 | 2024-07-29 | Bausch Health Ireland Limited | Ultra-oczyszczeni agoniści peptydowi cyklazy guanylanowej C, sposób ich uzyskiwania i ich zastosowanie |
| CA2920856C (en) | 2013-08-09 | 2026-03-03 | Ardelyx, Inc. | Ph modulating compounds for inhibiting gastrointestinal phosphate uptake |
| JP2022533251A (ja) | 2019-05-21 | 2022-07-21 | アルデリックス， インコーポレイテッド | 患者において血清リン酸塩を低下させるための組み合わせ |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5116430B2 (enExample) * | 1971-08-05 | 1976-05-24 | ||
| US3870792A (en) * | 1972-07-24 | 1975-03-11 | Michiro Inoue | Certain dihydrophthalizines for treating hemorrhage and thrombosis |
-
1974
- 1974-01-01 AR AR256326A patent/AR205004A1/es active
- 1974-09-03 IE IE1825/74A patent/IE39831B1/en unknown
- 1974-09-04 GB GB3870874A patent/GB1459606A/en not_active Expired
- 1974-09-10 US US05/504,745 patent/US3963716A/en not_active Expired - Lifetime
- 1974-09-16 IL IL45675A patent/IL45675A/xx unknown
- 1974-10-23 FR FR7435550A patent/FR2248841B1/fr not_active Expired
- 1974-10-24 CA CA212,163A patent/CA1029377A/en not_active Expired
- 1974-10-28 DK DK561874AA patent/DK134345B/da not_active IP Right Cessation
- 1974-10-28 LU LU71191A patent/LU71191A1/xx unknown
- 1974-10-28 SE SE7413530A patent/SE412389B/xx not_active IP Right Cessation
- 1974-10-29 FI FI3157/74A patent/FI59402C/fi active
- 1974-10-29 ES ES431454A patent/ES431454A1/es not_active Expired
- 1974-10-29 DE DE2451417A patent/DE2451417C3/de not_active Expired
- 1974-10-29 HU HUIO218A patent/HU168797B/hu unknown
- 1974-10-29 YU YU02897/74A patent/YU289774A/xx unknown
- 1974-10-30 CH CH1454674A patent/CH610892A5/xx not_active IP Right Cessation
- 1974-10-30 DD DD182046A patent/DD119231A5/xx unknown
- 1974-10-30 PH PH16465A patent/PH10519A/en unknown
- 1974-10-30 NL NL7414186A patent/NL7414186A/xx not_active Application Discontinuation
- 1974-10-30 CH CH497878A patent/CH611282A5/xx not_active IP Right Cessation
-
1976
- 1976-02-25 IN IN330/CAL/76A patent/IN139552B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| LU71191A1 (enExample) | 1975-04-17 |
| FI59402B (fi) | 1981-04-30 |
| AR205004A1 (es) | 1976-03-31 |
| PH10519A (en) | 1977-05-26 |
| DE2451417A1 (de) | 1975-05-07 |
| DK561874A (enExample) | 1975-07-07 |
| ES431454A1 (es) | 1976-10-16 |
| DE2451417C3 (de) | 1981-01-29 |
| IE39831L (en) | 1975-04-30 |
| FR2248841B1 (enExample) | 1978-07-28 |
| DK134345C (enExample) | 1977-03-21 |
| CH610892A5 (enExample) | 1979-05-15 |
| IN139552B (enExample) | 1976-07-03 |
| DD119231A5 (enExample) | 1976-04-12 |
| IL45675A (en) | 1978-10-31 |
| FR2248841A1 (enExample) | 1975-05-23 |
| HU168797B (enExample) | 1976-07-28 |
| US3963716A (en) | 1976-06-15 |
| FI315774A7 (enExample) | 1975-05-01 |
| IE39831B1 (en) | 1979-01-03 |
| GB1459606A (en) | 1976-12-22 |
| IL45675A0 (en) | 1974-11-29 |
| FI59402C (fi) | 1981-08-10 |
| DE2451417B2 (de) | 1980-05-14 |
| CH611282A5 (enExample) | 1979-05-31 |
| NL7414186A (nl) | 1975-05-02 |
| YU289774A (en) | 1983-01-21 |
| DK134345B (da) | 1976-10-25 |
| SE412389B (sv) | 1980-03-03 |
| AU7295474A (en) | 1976-03-11 |
| SE7413530L (enExample) | 1975-05-02 |
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