FR2240227A1 - Penam- and cepham derivs prepn - by reaction of substd isopropenyl azetidin derivs and nucleophilic cpds: antibacterial - Google Patents
Penam- and cepham derivs prepn - by reaction of substd isopropenyl azetidin derivs and nucleophilic cpds: antibacterialInfo
- Publication number
- FR2240227A1 FR2240227A1 FR7423880A FR7423880A FR2240227A1 FR 2240227 A1 FR2240227 A1 FR 2240227A1 FR 7423880 A FR7423880 A FR 7423880A FR 7423880 A FR7423880 A FR 7423880A FR 2240227 A1 FR2240227 A1 FR 2240227A1
- Authority
- FR
- France
- Prior art keywords
- derivs
- cpds
- reaction
- substd
- nucleophilic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000000844 anti-bacterial effect Effects 0.000 title abstract 2
- 238000006243 chemical reaction Methods 0.000 title abstract 2
- 230000000269 nucleophilic effect Effects 0.000 title abstract 2
- NLQIYOLRBNMSJT-UHFFFAOYSA-N 1-prop-1-en-2-ylazetidine Chemical compound CC(=C)N1CCC1 NLQIYOLRBNMSJT-UHFFFAOYSA-N 0.000 title 1
- QHTOIDKCEPKVCM-ZCFIWIBFSA-N cepham Chemical compound S1CCCN2C(=O)C[C@H]21 QHTOIDKCEPKVCM-ZCFIWIBFSA-N 0.000 title 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 3
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 abstract 2
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- UMGDCJDMYOKAJW-UHFFFAOYSA-N thiourea Chemical compound NC(N)=S UMGDCJDMYOKAJW-UHFFFAOYSA-N 0.000 abstract 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Natural products NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- RLDQYSHDFVSAPL-UHFFFAOYSA-L calcium;dithiocyanate Chemical compound [Ca+2].[S-]C#N.[S-]C#N RLDQYSHDFVSAPL-UHFFFAOYSA-L 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 150000002170 ethers Chemical class 0.000 abstract 1
- 239000012442 inert solvent Substances 0.000 abstract 1
- 150000004966 inorganic peroxy acids Chemical class 0.000 abstract 1
- VLAPMBHFAWRUQP-UHFFFAOYSA-L molybdic acid Chemical compound O[Mo](O)(=O)=O VLAPMBHFAWRUQP-UHFFFAOYSA-L 0.000 abstract 1
- 150000004967 organic peroxy acids Chemical class 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 150000003573 thiols Chemical class 0.000 abstract 1
- CMPGARWFYBADJI-UHFFFAOYSA-L tungstic acid Chemical compound O[W](O)(=O)=O CMPGARWFYBADJI-UHFFFAOYSA-L 0.000 abstract 1
- WQEVDHBJGNOKKO-UHFFFAOYSA-K vanadic acid Chemical compound O[V](O)(O)=O WQEVDHBJGNOKKO-UHFFFAOYSA-K 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
- C07D205/095—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4 and with a nitrogen atom directly attached in position 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP11738472A JPS5550955B2 (OSRAM) | 1972-11-22 | 1972-11-22 | |
| JP12557272A JPS5531789B2 (OSRAM) | 1972-12-13 | 1972-12-13 | |
| JP12557372A JPS5531791B2 (OSRAM) | 1972-12-13 | 1972-12-13 | |
| JP12663772A JPS5531794B2 (OSRAM) | 1972-12-15 | 1972-12-15 | |
| JP47128658A JPS5929597B2 (ja) | 1972-12-20 | 1972-12-20 | ２−置換アルキル−２−アルキルペナム−３−カルボン酸類の製造法 |
| JP12890272A JPS5641634B2 (OSRAM) | 1972-12-21 | 1972-12-21 | |
| JP731201A JPS5946950B2 (ja) | 1972-12-23 | 1972-12-23 | ３−置換セフアム−４−カルボン酸類を製造する方法 |
| JP48087108A JPS5946951B2 (ja) | 1973-08-01 | 1973-08-01 | ３−置換セフエム−４−カルボン酸−１−オキサイド類の製造法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2240227A1 true FR2240227A1 (en) | 1975-03-07 |
| FR2240227B1 FR2240227B1 (OSRAM) | 1977-11-25 |
Family
ID=27571429
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7423880A Granted FR2240227A1 (en) | 1972-11-22 | 1974-07-09 | Penam- and cepham derivs prepn - by reaction of substd isopropenyl azetidin derivs and nucleophilic cpds: antibacterial |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2240227A1 (OSRAM) |
-
1974
- 1974-07-09 FR FR7423880A patent/FR2240227A1/fr active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| FR2240227B1 (OSRAM) | 1977-11-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |