FR2229416A1 - Cyclocytidine improved freeze-dried prepns. - by freeze-drying solns. of cyclocytidine and a saccharide, polyvinylpyrrolidone etc. - Google Patents
Cyclocytidine improved freeze-dried prepns. - by freeze-drying solns. of cyclocytidine and a saccharide, polyvinylpyrrolidone etc.Info
- Publication number
- FR2229416A1 FR2229416A1 FR7417294A FR7417294A FR2229416A1 FR 2229416 A1 FR2229416 A1 FR 2229416A1 FR 7417294 A FR7417294 A FR 7417294A FR 7417294 A FR7417294 A FR 7417294A FR 2229416 A1 FR2229416 A1 FR 2229416A1
- Authority
- FR
- France
- Prior art keywords
- freeze
- cyclocytidine
- saccharide
- drying
- dried
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 229950000242 ancitabine Drugs 0.000 title abstract 3
- KZOWNALBTMILAP-JBMRGDGGSA-N ancitabine hydrochloride Chemical compound Cl.N=C1C=CN2[C@@H]3O[C@H](CO)[C@@H](O)[C@@H]3OC2=N1 KZOWNALBTMILAP-JBMRGDGGSA-N 0.000 title abstract 3
- 150000001720 carbohydrates Chemical class 0.000 title abstract 2
- 238000004108 freeze drying Methods 0.000 title abstract 2
- 229920000036 polyvinylpyrrolidone Polymers 0.000 title abstract 2
- 239000001267 polyvinylpyrrolidone Substances 0.000 title abstract 2
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 abstract 3
- 239000007864 aqueous solution Substances 0.000 abstract 2
- 239000000243 solution Substances 0.000 abstract 2
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 abstract 1
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- 239000001768 carboxy methyl cellulose Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000007918 intramuscular administration Methods 0.000 abstract 1
- 238000001990 intravenous administration Methods 0.000 abstract 1
- 231100000053 low toxicity Toxicity 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 abstract 1
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 abstract 1
- 238000007920 subcutaneous administration Methods 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
- 239000000080 wetting agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Molecular Biology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Preparation (AREA)
- Saccharide Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP5414573A JPS5637967B2 (enrdf_load_stackoverflow) | 1973-05-17 | 1973-05-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FR2229416A1 true FR2229416A1 (en) | 1974-12-13 |
Family
ID=12962379
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7417294A Withdrawn FR2229416A1 (en) | 1973-05-17 | 1974-05-17 | Cyclocytidine improved freeze-dried prepns. - by freeze-drying solns. of cyclocytidine and a saccharide, polyvinylpyrrolidone etc. |
Country Status (4)
| Country | Link |
|---|---|
| JP (1) | JPS5637967B2 (enrdf_load_stackoverflow) |
| DE (1) | DE2423811A1 (enrdf_load_stackoverflow) |
| ES (1) | ES426414A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2229416A1 (enrdf_load_stackoverflow) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2571962A1 (fr) * | 1984-10-24 | 1986-04-25 | Sandoz Sa | Nouvelles formulations galeniques a base de bromocriptine. |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS51139613A (en) * | 1975-05-24 | 1976-12-02 | Nippon Shinyaku Co Ltd | An absorbable non-crystalline sterol glycoside monopalmitate ester and a method for preparing its pharmaceutical |
| DE2658406C2 (de) * | 1975-12-31 | 1984-04-26 | Asahi Kasei Kogyo K.K., Osaka | Verfahren zur Herstellung wasserlöslicher Arzneimittelzubereitungen, enthaltend N↑4↑-Acylcytosin-arabinosid |
| ID21635A (id) * | 1996-12-20 | 1999-07-08 | Astra Pharma Prod | Komposisi farmasi untuk pengeringan beku |
| KR0181252B1 (ko) * | 1996-12-31 | 1999-03-20 | 박원훈 | 에멀젼 방법에 의한 다공성 매트릭스형 서방성 제제의 제조방법 |
| US6417167B1 (en) | 1997-02-05 | 2002-07-09 | Kirin Beer Kabushiki Kaisha | Lyophilized compositions containing shingoglycolipid and process for preparing them |
| ATE268180T1 (de) * | 1997-02-05 | 2004-06-15 | Kirin Brewery | Glycosphingolipide enthaltende gefriergetrocknete zusammensetzung |
| SE9702680D0 (sv) * | 1997-07-11 | 1997-07-11 | Astra Pharma Prod | New formulation |
-
1973
- 1973-05-17 JP JP5414573A patent/JPS5637967B2/ja not_active Expired
-
1974
- 1974-05-16 DE DE2423811A patent/DE2423811A1/de active Pending
- 1974-05-17 FR FR7417294A patent/FR2229416A1/fr not_active Withdrawn
- 1974-05-17 ES ES426414A patent/ES426414A1/es not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2571962A1 (fr) * | 1984-10-24 | 1986-04-25 | Sandoz Sa | Nouvelles formulations galeniques a base de bromocriptine. |
Also Published As
| Publication number | Publication date |
|---|---|
| DE2423811A1 (de) | 1974-12-05 |
| JPS505523A (enrdf_load_stackoverflow) | 1975-01-21 |
| ES426414A1 (es) | 1976-07-01 |
| JPS5637967B2 (enrdf_load_stackoverflow) | 1981-09-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |