FR2228483A2 - Esters and salts of 2-propylthiazole-5-carboxylic acid - vasodilators and hypolipidaemics - Google Patents

Esters and salts of 2-propylthiazole-5-carboxylic acid - vasodilators and hypolipidaemics

Info

Publication number
FR2228483A2
FR2228483A2 FR7317070A FR7317070A FR2228483A2 FR 2228483 A2 FR2228483 A2 FR 2228483A2 FR 7317070 A FR7317070 A FR 7317070A FR 7317070 A FR7317070 A FR 7317070A FR 2228483 A2 FR2228483 A2 FR 2228483A2
Authority
FR
France
Prior art keywords
hypolipidaemics
propylthiazole
vasodilators
esters
salts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7317070A
Other languages
French (fr)
Other versions
FR2228483B2 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to DE1936695A priority Critical patent/DE1936695C3/en
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Priority to FR7317070A priority patent/FR2228483A2/en
Priority to AR25365374A priority patent/AR204990A1/en
Priority to IL4478674A priority patent/IL44786A/en
Priority to HURO000779 priority patent/HU168854B/hu
Priority to ES426123A priority patent/ES426123A2/en
Priority to AU68796/74A priority patent/AU493931B2/en
Priority to BE144131A priority patent/BE814793R/en
Priority to LU70025A priority patent/LU70025A1/xx
Priority to JP5141574A priority patent/JPS5030870A/ja
Priority to CH646274A priority patent/CH602681A5/xx
Priority to NL7406356A priority patent/NL7406356A/xx
Priority to IE100374A priority patent/IE39262B1/en
Priority to DE2422849A priority patent/DE2422849A1/en
Priority to ZA00743004A priority patent/ZA743004B/en
Priority to CA199,737A priority patent/CA1023367A/en
Priority to GB2108874A priority patent/GB1432919A/en
Publication of FR2228483A2 publication Critical patent/FR2228483A2/en
Application granted granted Critical
Publication of FR2228483B2 publication Critical patent/FR2228483B2/fr
Priority to AR25850978A priority patent/AR212497A1/en
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Abstract

New title cpds. are of formula (I): (where R1=2,3-isopropylidenedioxypropyl, 2,3-dihydroxypropyl, morpholinoethyl (opt. as salt), benzyl, t-butyl, CH3 or an equivalent of Ca2+ or AlOH2+. Specif. C3H7 is linear. (I) are obtd. from free acid by reacting with R1OH to give an ester or by conventional salt formn.
FR7317070A 1969-06-11 1973-05-11 Esters and salts of 2-propylthiazole-5-carboxylic acid - vasodilators and hypolipidaemics Granted FR2228483A2 (en)

Priority Applications (18)

Application Number Priority Date Filing Date Title
DE1936695A DE1936695C3 (en) 1969-06-11 1969-07-18 2-n-PropyI-5-thiazolecarboxylic acid, its salts and esters, processes for their preparation and therapeutic compositions
FR7317070A FR2228483A2 (en) 1973-05-11 1973-05-11 Esters and salts of 2-propylthiazole-5-carboxylic acid - vasodilators and hypolipidaemics
AR25365374A AR204990A1 (en) 1973-05-11 1974-01-01 PROCEDURE FOR THE PREPARATION OF NEW DERIVATIVES OF 2-PROPYL-5-THIAZOL CARBOXYL ACID
HURO000779 HU168854B (en) 1973-05-11 1974-05-08
IL4478674A IL44786A (en) 1973-05-11 1974-05-08 Salts of 2-n-propyl 5-thiazolecarboxylic acid and pharmaceutical compositions containing same
AU68796/74A AU493931B2 (en) 1973-05-11 1974-05-09 Thiazole derivatives
BE144131A BE814793R (en) 1973-05-11 1974-05-09 NEW DERIVATIVES OF 5-THIAZOL CARBOXYLIC ACID AND PROCESS FOR OBTAINING
LU70025A LU70025A1 (en) 1973-05-11 1974-05-09
ES426123A ES426123A2 (en) 1973-05-11 1974-05-09 2-propyl-5-thiazole carboxylates
CH646274A CH602681A5 (en) 1973-05-11 1974-05-10
NL7406356A NL7406356A (en) 1973-05-11 1974-05-10
IE100374A IE39262B1 (en) 1973-05-11 1974-05-10 2-propyl-5-thiazole carboxylates
DE2422849A DE2422849A1 (en) 1969-06-11 1974-05-10 2-PROPYL-5-THIAZOLE CARBONIC ACID DERIVATIVES AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE COMPOUNDS
JP5141574A JPS5030870A (en) 1973-05-11 1974-05-10
ZA00743004A ZA743004B (en) 1973-05-11 1974-05-10 New derivatives of 2-propy@ 5-thiazole carboyylic acid and pharmaceutical compositions
CA199,737A CA1023367A (en) 1973-05-11 1974-05-10 Preparation of novel 2-propyl, 5-thiazol carboxylic acid derivatives
GB2108874A GB1432919A (en) 1973-05-11 1974-05-13 2-propyl-5-thiazole carboxylates
AR25850978A AR212497A1 (en) 1973-05-11 1978-04-25 PROCEDURE TO PREPARE CALCIUM 2-PROPYL-5-THIAZOL CARBOXYLATE AND ALUMINUM 2-PROPYL-5-THIAZOL-CARBOXYLATE BASIC SALT

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7317070A FR2228483A2 (en) 1973-05-11 1973-05-11 Esters and salts of 2-propylthiazole-5-carboxylic acid - vasodilators and hypolipidaemics

Publications (2)

Publication Number Publication Date
FR2228483A2 true FR2228483A2 (en) 1974-12-06
FR2228483B2 FR2228483B2 (en) 1976-05-14

Family

ID=9119166

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7317070A Granted FR2228483A2 (en) 1969-06-11 1973-05-11 Esters and salts of 2-propylthiazole-5-carboxylic acid - vasodilators and hypolipidaemics

Country Status (3)

Country Link
BE (1) BE814793R (en)
FR (1) FR2228483A2 (en)
ZA (1) ZA743004B (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2047876A1 (en) * 1969-06-11 1971-03-19 Roussel Uclaf

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2047876A1 (en) * 1969-06-11 1971-03-19 Roussel Uclaf

Also Published As

Publication number Publication date
ZA743004B (en) 1975-06-25
FR2228483B2 (en) 1976-05-14
BE814793R (en) 1974-11-12

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