ES384566A1 - Procedure to produce 9-alpha hydroxy acid or ester optically active. (Machine-translation by Google Translate, not legally binding) - Google Patents
Procedure to produce 9-alpha hydroxy acid or ester optically active. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES384566A1 ES384566A1 ES384566A ES384566A ES384566A1 ES 384566 A1 ES384566 A1 ES 384566A1 ES 384566 A ES384566 A ES 384566A ES 384566 A ES384566 A ES 384566A ES 384566 A1 ES384566 A1 ES 384566A1
- Authority
- ES
- Spain
- Prior art keywords
- translation
- procedure
- produce
- machine
- optically active
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229940061720 alpha hydroxy acid Drugs 0.000 title 1
- 150000002148 esters Chemical class 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000001153 fluoro group Chemical group F* 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 229940094443 oxytocics prostaglandins Drugs 0.000 abstract 1
- 150000003180 prostaglandins Chemical class 0.000 abstract 1
- 238000000926 separation method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
Abstract
Prostaglandins and derivatives thereof of the formula are prepared by hydrolysis and subsequent separation treatment of compounds of the formula wherein X is -CH 2 CH 2 - or trans -CH = CH-, and both Y and Z are -CH 2 CH 2 -, or wherein X is trans -CH=CH-, Y is cis -CH=CH- and Z is -CH 2 CH 2 - or cis -CH=CH-, A is C 1-4 alkyl, phenyl, phenyl substituted with 1 or 2 fluoro, chloro or C 1-4 alkyl, or C 7-12 aralkyl, R 1 is H, C 1-4 alkyl, or -Si(A) 3 , R 4 is H or C 1-4 alkyl and # indicates attachment of HO- to the ring in alpha or beta configuration.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87360369A | 1969-11-03 | 1969-11-03 | |
| US6092870A | 1970-08-04 | 1970-08-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES384566A1 true ES384566A1 (en) | 1973-05-01 |
Family
ID=26740510
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES384566A Expired ES384566A1 (en) | 1969-11-03 | 1970-10-15 | Procedure to produce 9-alpha hydroxy acid or ester optically active. (Machine-translation by Google Translate, not legally binding) |
Country Status (14)
| Country | Link |
|---|---|
| JP (1) | JPS5144942B1 (en) |
| BE (1) | BE758394A (en) |
| CH (1) | CH532007A (en) |
| DE (1) | DE2053583A1 (en) |
| DK (1) | DK129000B (en) |
| ES (1) | ES384566A1 (en) |
| FI (1) | FI51346C (en) |
| FR (1) | FR2068366A5 (en) |
| GB (1) | GB1266988A (en) |
| IL (1) | IL35423A (en) |
| NL (1) | NL7015367A (en) |
| NO (1) | NO129251B (en) |
| PH (2) | PH9726A (en) |
| SE (1) | SE385879B (en) |
-
0
- BE BE758394D patent/BE758394A/en unknown
-
1970
- 1970-10-07 GB GB1266988D patent/GB1266988A/en not_active Expired
- 1970-10-08 PH PH11856*UA patent/PH9726A/en unknown
- 1970-10-09 IL IL35423A patent/IL35423A/en unknown
- 1970-10-12 CH CH1513770A patent/CH532007A/en not_active IP Right Cessation
- 1970-10-14 JP JP45089782A patent/JPS5144942B1/ja active Pending
- 1970-10-15 ES ES384566A patent/ES384566A1/en not_active Expired
- 1970-10-20 NL NL7015367A patent/NL7015367A/xx unknown
- 1970-10-26 FI FI702878A patent/FI51346C/en not_active IP Right Cessation
- 1970-10-29 SE SE7014623A patent/SE385879B/en unknown
- 1970-10-30 NO NO04134/70A patent/NO129251B/no unknown
- 1970-10-31 DE DE19702053583 patent/DE2053583A1/en active Pending
- 1970-11-02 FR FR7039398A patent/FR2068366A5/fr not_active Expired
- 1970-11-02 DK DK555970AA patent/DK129000B/en unknown
-
1973
- 1973-09-20 PH PH15039*UA patent/PH9732A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SE385879B (en) | 1976-07-26 |
| FR2068366A5 (en) | 1971-08-20 |
| NL7015367A (en) | 1971-05-05 |
| BE758394A (en) | 1971-05-03 |
| FI51346B (en) | 1976-08-31 |
| PH9726A (en) | 1976-02-27 |
| IL35423A0 (en) | 1970-12-24 |
| PH9732A (en) | 1976-02-27 |
| FI51346C (en) | 1976-12-10 |
| DE2053583A1 (en) | 1971-07-15 |
| NO129251B (en) | 1974-03-18 |
| JPS5144942B1 (en) | 1976-12-01 |
| GB1266988A (en) | 1972-03-15 |
| CH532007A (en) | 1972-12-31 |
| IL35423A (en) | 1974-07-31 |
| DK129000B (en) | 1974-08-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB1432576A (en) | Substituted phenylacetic acids | |
| GB1409843A (en) | Prostaglandin intermediates | |
| SE7613651L (en) | WAY TO PREPARE PHENYLETIC ACID DERIVATIVES | |
| FR2414508A1 (en) | CEPHALOSPORINS PRODUCTION PROCESS | |
| GB1212090A (en) | Aliphatic diol-diones | |
| FR2355822A1 (en) | INDOLACETIC ACID ESTERS DERIVATIVES. USEFUL AS ANTI-INFLAMMATORY AND ANALGESICS | |
| GB1496492A (en) | Optically active lysergic acid derivatives | |
| ES388885A1 (en) | 1-(2'-cyano-phenoxy)-2-hydroxy-3-ethylamino-propane and salts thereof | |
| ES384566A1 (en) | Procedure to produce 9-alpha hydroxy acid or ester optically active. (Machine-translation by Google Translate, not legally binding) | |
| GB1250558A (en) | ||
| ES376067A1 (en) | Substituted 1-indancarboxylic acids, their esters and salts | |
| GB1360164A (en) | 3,5-dialkyl-4-hydroxyphenylalkanoic acid esters of hydroxyalkyl hydroxyalkanoates | |
| FR2428628A1 (en) | MERCAPTOPROPIONYLGLYCIN SODIUM SALT, PROCESS FOR ITS PREPARATION AND THERAPEUTIC USES | |
| GB1515614A (en) | Preparation of m-benzoylhydratropic acid and an intermediate therefor | |
| GB1292662A (en) | Bicycloheptaneheptanoic acids and esters thereof | |
| GB1296655A (en) | ||
| FR2427323A1 (en) | NEW ESTERS OF SAFRANIC ACIDS | |
| FR2420538A1 (en) | 7-ACYLAMINO-1-CARBA-3-CEPHEM-4-CARBOXYLIC ACIDS, AS COMPOUNDS SIMILAR TO CEPHALOSPORIN, AND PROCESS FOR THE PREPARATION | |
| BE814269A (en) | COMPOSITION OF ACRYLIC ACID STABILIZED BY PHENOLS ALKYL | |
| ES395036A2 (en) | Prostaglandins and the preparation thereof | |
| FR2395250A1 (en) | DERIVATIVES OF AMINO- GUANIDINO-PHENYLPROPIONIC ACIDS | |
| ES343416A1 (en) | 1-substituted-2-alkyl-5-nitroimidazoles | |
| GB1268008A (en) | ESTERS OF p-BYPHENYLYLACETIC ACID | |
| ES394667A1 (en) | Preparation of prostanoic acid derivatives | |
| GB1386870A (en) | Prostaglandins and the preparation thereof |