FR2224148A2 - - Google Patents

Info

Publication number
FR2224148A2
FR2224148A2 FR7320618A FR7320618A FR2224148A2 FR 2224148 A2 FR2224148 A2 FR 2224148A2 FR 7320618 A FR7320618 A FR 7320618A FR 7320618 A FR7320618 A FR 7320618A FR 2224148 A2 FR2224148 A2 FR 2224148A2
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7320618A
Other versions
FR2224148B2 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Continental Pharma Inc
Original Assignee
Continental Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Continental Pharma Inc filed Critical Continental Pharma Inc
Publication of FR2224148A2 publication Critical patent/FR2224148A2/fr
Application granted granted Critical
Publication of FR2224148B2 publication Critical patent/FR2224148B2/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/092—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings with aromatic radicals attached to the chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
FR7320618A 1973-04-09 1973-06-06 Expired FR2224148B2 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1700173A GB1390748A (en) 1973-04-09 1973-04-09 Alkyl and cycloalkylthiophenylalkylaminoalkanols their salts and the preparation thereof

Publications (2)

Publication Number Publication Date
FR2224148A2 true FR2224148A2 (fr) 1974-10-31
FR2224148B2 FR2224148B2 (fr) 1976-10-22

Family

ID=10087466

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7320618A Expired FR2224148B2 (fr) 1973-04-09 1973-06-06

Country Status (11)

Country Link
US (1) US4228187A (fr)
JP (1) JPS5221497B2 (fr)
BE (1) BE799379R (fr)
CH (1) CH555315A (fr)
DE (2) DE2334404C2 (fr)
ES (1) ES425084A2 (fr)
FR (1) FR2224148B2 (fr)
GB (1) GB1390748A (fr)
IL (1) IL42448A (fr)
NL (1) NL164025C (fr)
ZA (1) ZA742227B (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2400360A1 (fr) * 1975-07-14 1979-03-16 Merck & Co Inc Comprimes a tons multiples et leur procede de preparation
EP0066919A1 (fr) * 1981-05-27 1982-12-15 MAGGIONI FARMACEUTICI S.p.A. Alcoyl-thio-4-phényl-éthanolamines, ayant une activité sur la circulation cérébrale, sur l'agrégation des plaquettes sanguines et sur la lipémie

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2353288A1 (fr) * 1976-06-04 1977-12-30 Continental Pharma Composition pharmaceutique hydrosoluble a base d'un compose amine comme produit actif
DE2817494A1 (de) * 1977-05-03 1978-11-09 Continental Pharma Aminoalkohol-derivat
US4404222A (en) * 1980-08-25 1983-09-13 American Cyanamid Company Phenylethanolamine derivatives and acid addition salts thereof for enhancing the growth rate of meat-producing animals and improving the efficiency of feed utilization thereby
DE3128117A1 (de) * 1980-07-29 1982-03-11 Yamanouchi Pharmaceutical Co., Ltd., Tokyo Neue phenyl-aethylaminderivate, verfahren zu ihrer herstellung
US4407819A (en) * 1980-08-25 1983-10-04 American Cyanamid Company Phenylethanolamine derivatives and acid addition salts thereof for the depression of fat deposition in warm blooded animals
US4432995A (en) * 1980-12-22 1984-02-21 American Cyanamid Company 5-[2-(Ethylamino)-1-hydroxylethyl] anthranilonitrile and the use thereof in meat producing animals
LU83039A1 (fr) * 1980-12-24 1982-07-07 Continental Pharma Procedes de synthese du 1-(4 isopropylthiophenyl)-2-n octylaminopropanol
AT380874B (de) * 1980-12-24 1986-07-25 Continental Pharma Verfahren zur herstellung von 1-(4-isopropylthiophenyl)-2-n.octyl-amino-propanol, dessen saeureadditionssalzen und estern
AT380873B (de) * 1980-12-24 1986-07-25 Continental Pharma Verfahren zur herstellung von 1-(4-isopropylthiophenyl)-2-n.octyl-amino -propanol, dessen saeureadditionssalzen und estern
IT1198386B (it) * 1982-07-06 1988-12-21 Lepetit Spa Un prodotto a rilascio protratto contenente il suloctidile
FR2534580A1 (fr) * 1982-10-13 1984-04-20 Synthelabo Derives de phenyl-1 piperidino-2 propanol, leur preparation, et medicaments qui les contiennent
US5552442A (en) * 1987-09-15 1996-09-03 The Rowett Research Institute Therapeutic applications of clenbuterol
US5530029A (en) * 1987-09-15 1996-06-25 The Rowett Research Institute Therapeutic applications of clenbuterol
MXPA05001958A (es) 2002-08-19 2005-04-28 Pfizer Prod Inc Terapia de combinacion para enfermedades hiperproliferativas.
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
CN101663262B (zh) 2006-12-01 2014-03-26 百时美施贵宝公司 用于治疗动脉粥样硬化和心血管疾病的作为cetp抑制剂的n-(3-苄基)-2,2-(二苯基)-丙-1胺衍生物
GB201015079D0 (en) * 2010-09-10 2010-10-27 Helperby Therapeutics Ltd Novel use
CN105143203A (zh) 2013-04-17 2015-12-09 辉瑞大药厂 用于治疗心血管疾病的n-哌啶-3-基苯甲酰胺衍生物
WO2016055901A1 (fr) 2014-10-08 2016-04-14 Pfizer Inc. Composés d'amide substitué
CN113574055B (zh) 2019-01-18 2024-07-23 阿斯利康(瑞典)有限公司 Pcsk9抑制剂及其使用方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1321701A (en) * 1969-10-01 1973-06-27 Continental Pharma Amino-alcohols their salts and process for prepairing the same

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2400360A1 (fr) * 1975-07-14 1979-03-16 Merck & Co Inc Comprimes a tons multiples et leur procede de preparation
EP0066919A1 (fr) * 1981-05-27 1982-12-15 MAGGIONI FARMACEUTICI S.p.A. Alcoyl-thio-4-phényl-éthanolamines, ayant une activité sur la circulation cérébrale, sur l'agrégation des plaquettes sanguines et sur la lipémie
US4587248A (en) * 1981-05-27 1986-05-06 Giorgio Cantarelli 4-alkyl-thiophenyl-ethanolamines, having an activity the cerebral circulation, the blood platelet-aggregation and the lipenia

Also Published As

Publication number Publication date
NL7307401A (fr) 1974-10-11
IL42448A (en) 1976-09-30
DE2366338C2 (de) 1982-06-16
JPS49135935A (fr) 1974-12-27
BE799379R (fr) 1973-11-12
CH555315A (fr) 1974-10-31
ES425084A2 (es) 1976-12-16
US4228187A (en) 1980-10-14
ZA742227B (en) 1975-06-25
DE2334404A1 (de) 1974-10-24
JPS5221497B2 (fr) 1977-06-10
NL164025C (nl) 1980-11-17
FR2224148B2 (fr) 1976-10-22
DE2334404C2 (de) 1982-10-28
GB1390748A (en) 1975-04-16
NL164025B (nl) 1980-06-16
IL42448A0 (en) 1973-08-29

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Legal Events

Date Code Title Description
TP Transmission of property