FR2220260A1 - - Google Patents

Info

Publication number
FR2220260A1
FR2220260A1 FR7407444A FR7407444A FR2220260A1 FR 2220260 A1 FR2220260 A1 FR 2220260A1 FR 7407444 A FR7407444 A FR 7407444A FR 7407444 A FR7407444 A FR 7407444A FR 2220260 A1 FR2220260 A1 FR 2220260A1
Authority
FR
France
Prior art keywords
araliphatic
cycloaliphatic
group
aliphatic
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7407444A
Other languages
French (fr)
Other versions
FR2220260B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Laboratories Ltd
Original Assignee
Glaxo Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB1089473A external-priority patent/GB1468349A/en
Application filed by Glaxo Laboratories Ltd filed Critical Glaxo Laboratories Ltd
Publication of FR2220260A1 publication Critical patent/FR2220260A1/fr
Application granted granted Critical
Publication of FR2220260B1 publication Critical patent/FR2220260B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Compounds of the formula I in which R denotes a group of the formula -(CH2)n-NR1R2, where R1 and R2, which are identical or different, each denote an aliphatic, cycloaliphatic, araliphatic or aromatic group, where one of the symbols R1 and R2 can additionally represent a hydrogen atom, or, together with the nitrogen atom to which they are bonded, form a heterocyclic ring and n is zero or 1, where carbon atom 10 can be substituted by one or two aliphatic, cycloaliphatic, araliphatic or aromatic groups, and their physiologically acceptable salts are prepared by reducing a corresponding compound which carries a carbonyl group in the position alpha to the nitrogen atom, and optionally then converting the process products into their physiologically acceptable salts. The novel compounds are distinguished in particular by their activity against viruses, e.g. influenza viruses.
FR7407444A 1973-03-06 1974-03-05 Expired FR2220260B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB1089473A GB1468349A (en) 1973-03-06 1973-03-06 10-bornanamine and 7,7-dimethyl-norbornan-1-amine and derivatives thereof
GB1089573 1973-03-06

Publications (2)

Publication Number Publication Date
FR2220260A1 true FR2220260A1 (en) 1974-10-04
FR2220260B1 FR2220260B1 (en) 1977-03-11

Family

ID=26247839

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7407444A Expired FR2220260B1 (en) 1973-03-06 1974-03-05

Country Status (9)

Country Link
JP (1) JPS5029547A (en)
AT (1) AT353247B (en)
CA (1) CA1064928A (en)
CH (1) CH616646A5 (en)
DE (1) DE2410492A1 (en)
FR (1) FR2220260B1 (en)
IE (1) IE39712B1 (en)
LU (1) LU69557A1 (en)
NL (1) NL7402940A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2362778A1 (en) * 1999-03-03 2000-09-08 Merck & Co., Inc. Inhibitors of prenyl-protein transferase

Also Published As

Publication number Publication date
CH616646A5 (en) 1980-04-15
DE2410492A1 (en) 1974-09-26
CA1064928A (en) 1979-10-23
FR2220260B1 (en) 1977-03-11
ATA179774A (en) 1979-04-15
AU6628074A (en) 1975-09-11
IE39712B1 (en) 1978-12-20
NL7402940A (en) 1974-09-10
AT353247B (en) 1979-11-12
LU69557A1 (en) 1974-06-21
JPS5029547A (en) 1975-03-25
IE39712L (en) 1974-09-06

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Legal Events

Date Code Title Description
ST Notification of lapse