FR2212152A1 - 21-Adamantane-1-carboxylates of betamethasone - and analogs, with long-lasting anti-inflammatory/immunosuppressive activity - Google Patents
21-Adamantane-1-carboxylates of betamethasone - and analogs, with long-lasting anti-inflammatory/immunosuppressive activityInfo
- Publication number
- FR2212152A1 FR2212152A1 FR7400066A FR7400066A FR2212152A1 FR 2212152 A1 FR2212152 A1 FR 2212152A1 FR 7400066 A FR7400066 A FR 7400066A FR 7400066 A FR7400066 A FR 7400066A FR 2212152 A1 FR2212152 A1 FR 2212152A1
- Authority
- FR
- France
- Prior art keywords
- adamantane
- betamethasone
- carboxylates
- analogs
- inflammatory
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000003110 anti-inflammatory effect Effects 0.000 title abstract 2
- 229960002537 betamethasone Drugs 0.000 title abstract 2
- UREBDLICKHMUKA-DVTGEIKXSA-N betamethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-DVTGEIKXSA-N 0.000 title abstract 2
- 230000000947 anti-immunosuppressive effect Effects 0.000 title 1
- 230000005923 long-lasting effect Effects 0.000 title 1
- ORILYTVJVMAKLC-UHFFFAOYSA-N adamantane Chemical compound C1C(C2)CC3CC1CC2C3 ORILYTVJVMAKLC-UHFFFAOYSA-N 0.000 abstract 2
- 229960003957 dexamethasone Drugs 0.000 abstract 2
- UREBDLICKHMUKA-CXSFZGCWSA-N dexamethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-CXSFZGCWSA-N 0.000 abstract 2
- 230000001506 immunosuppresive effect Effects 0.000 abstract 1
- 230000002045 lasting effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB44773 | 1973-01-03 | ||
| GB44873 | 1973-01-03 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2212152A1 true FR2212152A1 (en) | 1974-07-26 |
| FR2212152B1 FR2212152B1 (cg-RX-API-DMAC7.html) | 1977-03-25 |
Family
ID=26235930
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7400066A Granted FR2212152A1 (en) | 1973-01-03 | 1974-01-02 | 21-Adamantane-1-carboxylates of betamethasone - and analogs, with long-lasting anti-inflammatory/immunosuppressive activity |
| FR7400067A Expired FR2212153B1 (cg-RX-API-DMAC7.html) | 1973-01-03 | 1974-01-02 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7400067A Expired FR2212153B1 (cg-RX-API-DMAC7.html) | 1973-01-03 | 1974-01-02 |
Country Status (9)
| Country | Link |
|---|---|
| JP (2) | JPS5024427A (cg-RX-API-DMAC7.html) |
| AU (2) | AU6420274A (cg-RX-API-DMAC7.html) |
| BE (2) | BE809342A (cg-RX-API-DMAC7.html) |
| DE (2) | DE2400038A1 (cg-RX-API-DMAC7.html) |
| FR (2) | FR2212152A1 (cg-RX-API-DMAC7.html) |
| IL (2) | IL43948A (cg-RX-API-DMAC7.html) |
| LU (2) | LU69096A1 (cg-RX-API-DMAC7.html) |
| NL (2) | NL7400014A (cg-RX-API-DMAC7.html) |
| SE (1) | SE7400020L (cg-RX-API-DMAC7.html) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60161914A (ja) * | 1984-02-02 | 1985-08-23 | Green Cross Corp:The | ステロイド脂肪酸エステル含有直腸投与製剤 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1473909A (fr) * | 1965-11-16 | 1967-03-24 | Lilly Co Eli | Procédé de préparation de nouveaux esters de corticostéroïdes |
| FR2144761A1 (cg-RX-API-DMAC7.html) * | 1971-07-05 | 1973-02-16 | Glaxo Lab Ltd |
-
1973
- 1973-12-27 JP JP48144564A patent/JPS5024427A/ja active Pending
- 1973-12-27 JP JP48144563A patent/JPS49116217A/ja active Pending
-
1974
- 1974-01-02 BE BE139473A patent/BE809342A/xx unknown
- 1974-01-02 SE SE7400020A patent/SE7400020L/xx not_active Application Discontinuation
- 1974-01-02 LU LU69096A patent/LU69096A1/xx unknown
- 1974-01-02 NL NL7400014A patent/NL7400014A/xx unknown
- 1974-01-02 DE DE2400038A patent/DE2400038A1/de active Pending
- 1974-01-02 LU LU69097A patent/LU69097A1/xx unknown
- 1974-01-02 BE BE139472A patent/BE809341A/xx unknown
- 1974-01-02 NL NL7400013A patent/NL7400013A/xx unknown
- 1974-01-02 IL IL43948A patent/IL43948A/en unknown
- 1974-01-02 FR FR7400066A patent/FR2212152A1/fr active Granted
- 1974-01-02 IL IL43947A patent/IL43947A/en unknown
- 1974-01-02 DE DE2400005A patent/DE2400005A1/de active Pending
- 1974-01-02 FR FR7400067A patent/FR2212153B1/fr not_active Expired
- 1974-01-04 AU AU64202/74A patent/AU6420274A/en not_active Expired
- 1974-01-04 AU AU64201/74A patent/AU6420174A/en not_active Expired
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1473909A (fr) * | 1965-11-16 | 1967-03-24 | Lilly Co Eli | Procédé de préparation de nouveaux esters de corticostéroïdes |
| FR2144761A1 (cg-RX-API-DMAC7.html) * | 1971-07-05 | 1973-02-16 | Glaxo Lab Ltd |
Also Published As
| Publication number | Publication date |
|---|---|
| AU6420174A (en) | 1975-07-10 |
| IL43948A0 (en) | 1974-05-16 |
| IL43947A (en) | 1977-08-31 |
| AU6420274A (en) | 1975-07-10 |
| NL7400013A (cg-RX-API-DMAC7.html) | 1974-07-05 |
| DE2400038A1 (de) | 1974-07-04 |
| SE7400020L (cg-RX-API-DMAC7.html) | 1974-07-03 |
| BE809342A (fr) | 1974-07-02 |
| FR2212152B1 (cg-RX-API-DMAC7.html) | 1977-03-25 |
| DE2400005A1 (de) | 1974-07-04 |
| LU69096A1 (cg-RX-API-DMAC7.html) | 1974-04-02 |
| FR2212153B1 (cg-RX-API-DMAC7.html) | 1976-12-17 |
| JPS5024427A (cg-RX-API-DMAC7.html) | 1975-03-15 |
| IL43948A (en) | 1977-08-31 |
| BE809341A (fr) | 1974-07-02 |
| IL43947A0 (en) | 1974-05-16 |
| JPS49116217A (cg-RX-API-DMAC7.html) | 1974-11-06 |
| FR2212153A1 (cg-RX-API-DMAC7.html) | 1974-07-26 |
| NL7400014A (cg-RX-API-DMAC7.html) | 1974-07-05 |
| LU69097A1 (cg-RX-API-DMAC7.html) | 1974-04-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |