FR2208885B1 - - Google Patents

Info

Publication number
FR2208885B1
FR2208885B1 FR7333067A FR7333067A FR2208885B1 FR 2208885 B1 FR2208885 B1 FR 2208885B1 FR 7333067 A FR7333067 A FR 7333067A FR 7333067 A FR7333067 A FR 7333067A FR 2208885 B1 FR2208885 B1 FR 2208885B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7333067A
Other languages
French (fr)
Other versions
FR2208885A1 (US07696358-20100413-C00002.png
Inventor
Luigi Bernardi
Vincenzo Colonna
Roberto De Castiglione
Paolo Masi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmaceutici Italia SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmaceutici Italia SpA filed Critical Farmaceutici Italia SpA
Publication of FR2208885A1 publication Critical patent/FR2208885A1/fr
Application granted granted Critical
Publication of FR2208885B1 publication Critical patent/FR2208885B1/fr
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
FR7333067A 1972-09-18 1973-09-14 Expired FR2208885B1 (US07696358-20100413-C00002.png)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2932872 1972-09-18

Publications (2)

Publication Number Publication Date
FR2208885A1 FR2208885A1 (US07696358-20100413-C00002.png) 1974-06-28
FR2208885B1 true FR2208885B1 (US07696358-20100413-C00002.png) 1977-05-20

Family

ID=11226772

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7333067A Expired FR2208885B1 (US07696358-20100413-C00002.png) 1972-09-18 1973-09-14

Country Status (14)

Country Link
US (1) US3901942A (US07696358-20100413-C00002.png)
JP (1) JPS5741458B2 (US07696358-20100413-C00002.png)
AT (1) AT328613B (US07696358-20100413-C00002.png)
BE (1) BE804913A (US07696358-20100413-C00002.png)
CA (1) CA999855A (US07696358-20100413-C00002.png)
DE (1) DE2346535C3 (US07696358-20100413-C00002.png)
ES (1) ES418809A1 (US07696358-20100413-C00002.png)
FR (1) FR2208885B1 (US07696358-20100413-C00002.png)
GB (1) GB1413347A (US07696358-20100413-C00002.png)
HU (1) HU167850B (US07696358-20100413-C00002.png)
IE (1) IE38820B1 (US07696358-20100413-C00002.png)
NL (1) NL158172B (US07696358-20100413-C00002.png)
SU (1) SU574145A3 (US07696358-20100413-C00002.png)
ZA (1) ZA737317B (US07696358-20100413-C00002.png)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7696358B2 (en) 2001-03-13 2010-04-13 Paratek Pharmaceuticals, Inc. Five-membered heterocyclyl tetracycline compounds and methods of use thereof
US8048867B2 (en) 2000-07-07 2011-11-01 Trustees Of Tufts College 9-substituted minocycline compounds

Families Citing this family (34)

* Cited by examiner, † Cited by third party
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DE2437487A1 (de) * 1974-08-03 1976-02-19 Merck Patent Gmbh 7-methoxy-6-thia-tetracycline und verfahren zu ihrer herstellung
AU578068B2 (en) * 1984-03-08 1988-10-13 Nippon Zoki Pharmaceutical Co., Ltd. Hydantoin derivatives and pharmaceutical compositions containing them
JPH0737433B2 (ja) * 1987-06-11 1995-04-26 協和醗酵工業株式会社 7−アミノ−6−デメチル−6−デオキシテトラサイクリンの製造法
US4837030A (en) * 1987-10-06 1989-06-06 American Cyanamid Company Novel controlled release formulations of tetracycline compounds
JPH01116549U (US07696358-20100413-C00002.png) * 1988-01-29 1989-08-07
US5281628A (en) * 1991-10-04 1994-01-25 American Cyanamid Company 9-amino-7-(substituted)-6-demethyl-6-deoxytetracyclines
USRE40183E1 (en) 1991-10-04 2008-03-25 Wyeth Holdings Corporation 7-Substituted-9-substituted amino-6-demethyl-6-deoxytetracyclines
US5494903A (en) 1991-10-04 1996-02-27 American Cyanamid Company 7-substituted-9-substituted amino-6-demethyl-6-deoxytetracyclines
US5675030A (en) * 1994-11-16 1997-10-07 American Cyanamid Company Method for selective extracting a 7-(hydrogen or substituted amino)-9- (substituted glycyl) amido!-6-demethyl-6-deoxytetracycline compound
IL137445A0 (en) * 1998-01-23 2001-07-24 Tufts College Pharmaceutically active compounds and methods of use thereof
US8106225B2 (en) * 1999-09-14 2012-01-31 Trustees Of Tufts College Methods of preparing substituted tetracyclines with transition metal-based chemistries
CA2383364C (en) * 1999-09-14 2009-11-17 Trustees Of Tufts College Methods of preparing substituted tetracyclines with transition metal-based chemistries
US20040224927A1 (en) 2000-06-16 2004-11-11 Trustees Of Tufts College 7-N-substituted phenyl tetracycline compounds
WO2001098236A2 (en) * 2000-06-16 2001-12-27 Trustees Of Tufts College 7-phenyl-substituted tetracycline compounds
US20020132798A1 (en) * 2000-06-16 2002-09-19 Nelson Mark L. 7-phenyl-substituted tetracycline compounds
IL153672A0 (en) 2000-07-07 2003-07-06 Tufts College 7-substituted tetracycline compounds
US7094806B2 (en) * 2000-07-07 2006-08-22 Trustees Of Tufts College 7, 8 and 9-substituted tetracycline compounds
US7553828B2 (en) 2001-03-13 2009-06-30 Paratek Pharmaceuticals, Inc. 9-aminomethyl substituted minocycline compounds
CZ20032780A3 (cs) * 2001-03-13 2004-01-14 Paratek Pharmaceuticals, Inc. 7,9- Substituované tetracyklinové sloučeniny
CA2444899C (en) * 2001-04-24 2011-06-21 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for the treatment of malaria
US20030181371A1 (en) * 2001-12-28 2003-09-25 Angiotech Pharmaceuticals, Inc. Compositions and methods of using collajolie
EP2311797A1 (en) * 2002-01-08 2011-04-20 Paratek Pharmaceuticals, Inc. 4-dedimethylamino tetracycline compounds
EP2316450A1 (en) * 2002-03-08 2011-05-04 Paratek Pharmaceuticals, Inc. Amino-methyl substituted tetracycline compounds
CN1653037A (zh) * 2002-03-21 2005-08-10 帕拉特克药品公司 取代的四环素化合物
US20060287283A1 (en) * 2003-07-09 2006-12-21 Paratek Pharmaceuticals, Inc. Prodrugs of 9-aminomethyl tetracycline compounds
CN101863841A (zh) 2003-07-09 2010-10-20 帕拉特克药品公司 取代的四环素化合物
JP2008530023A (ja) 2005-02-04 2008-08-07 パラテック ファーマシューティカルズ インコーポレイテッド テトラサイクリン化合物の11a,12−誘導体
PT2109602E (pt) 2006-12-21 2014-05-23 Paratek Pharm Innc Derivados de tetraciclina para o tratamento de infecções bacterianas, virais e parasitárias
CA2892739A1 (en) 2006-12-21 2008-07-03 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for treatment of inflammatory skin disorders
PT103661B (pt) * 2007-02-23 2010-09-07 Hovione Farmaciencia S A Processo de preparação de minociclina base cristalina
US7935687B2 (en) 2007-04-12 2011-05-03 Paratek Pharmaceuticals, Inc. Methods for treating spinal muscular atrophy using tetracycline compounds
CA2717703A1 (en) 2008-03-05 2009-09-11 Paratek Pharmaceuticals, Inc. Minocycline compounds and methods of use thereof
TW202216656A (zh) * 2008-05-23 2022-05-01 美商Prtk Spv2公司 四環素化合物之甲苯磺酸鹽及同素異形體
US10383884B2 (en) 2016-11-01 2019-08-20 Paratek Pharmaceuticals, Inc. 9-aminomethyl minocycline compounds and use thereof in treating community-acquired bacterial pneumonia (CABP)

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2895993A (en) * 1957-05-16 1959-07-21 Pfizer & Co C Alkyl substituted anhydrotetracycline compounds and process of preparing the same
US2997471A (en) * 1958-08-18 1961-08-22 Bristol Myers Co Tetracycline derivatives
US3029284A (en) * 1960-09-14 1962-04-10 Pfizer & Co C Nu-dealkylation of carboxamido-nu-alkyltetracycline and its analogs
US3239499A (en) * 1961-05-19 1966-03-08 Pfizer & Co C Tetracycline derivative
US3165551A (en) * 1961-06-26 1965-01-12 Pfizer & Co C New antibacterial agents
US3148212A (en) * 1961-12-22 1964-09-08 American Cyanamid Co Reductive alkylation process
USRE26253E (en) * 1963-05-17 1967-08-15 And z-alkylamino-g-deoxytetracycline
US3388162A (en) * 1966-03-14 1968-06-11 American Cyanamid Co 7-and/or 9-nitro or amino tetracyclines
US3403179A (en) * 1967-01-10 1968-09-24 American Cyanamid Co Novel 7-(1, 2-bis-substituted-hydrazino)-tetracyclines and methods of preparing same
US3483251A (en) * 1967-03-03 1969-12-09 American Cyanamid Co Reductive alkylation process
US3373196A (en) * 1967-03-21 1968-03-12 American Cyanamid Co 7-and/or 9-(lower alkyl) amino-5a, 6-anhydrotetracyclines

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8048867B2 (en) 2000-07-07 2011-11-01 Trustees Of Tufts College 9-substituted minocycline compounds
US7696358B2 (en) 2001-03-13 2010-04-13 Paratek Pharmaceuticals, Inc. Five-membered heterocyclyl tetracycline compounds and methods of use thereof

Also Published As

Publication number Publication date
AU6033373A (en) 1975-03-20
NL158172B (nl) 1978-10-16
IE38820B1 (en) 1978-06-07
US3901942A (en) 1975-08-26
ATA799673A (de) 1975-06-15
ES418809A1 (es) 1976-03-16
DE2346535A1 (de) 1974-04-11
IE38820L (en) 1974-03-18
ZA737317B (en) 1974-09-25
BE804913A (fr) 1974-03-18
JPS4969653A (US07696358-20100413-C00002.png) 1974-07-05
CA999855A (en) 1976-11-16
AT328613B (de) 1976-03-25
GB1413347A (en) 1975-11-12
DE2346535B2 (de) 1980-09-11
NL7312648A (US07696358-20100413-C00002.png) 1974-03-20
SU574145A3 (ru) 1977-09-25
DE2346535C3 (de) 1981-05-21
JPS5741458B2 (US07696358-20100413-C00002.png) 1982-09-03
HU167850B (US07696358-20100413-C00002.png) 1975-12-25
FR2208885A1 (US07696358-20100413-C00002.png) 1974-06-28

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Legal Events

Date Code Title Description
ST Notification of lapse