FR2205333A1 - 6-Phenanthridone-3-carboxylic or-acetic acids - useful as gastric sec-retion inhibitors and anti-ulcer agents - Google Patents
6-Phenanthridone-3-carboxylic or-acetic acids - useful as gastric sec-retion inhibitors and anti-ulcer agentsInfo
- Publication number
- FR2205333A1 FR2205333A1 FR7339363A FR7339363A FR2205333A1 FR 2205333 A1 FR2205333 A1 FR 2205333A1 FR 7339363 A FR7339363 A FR 7339363A FR 7339363 A FR7339363 A FR 7339363A FR 2205333 A1 FR2205333 A1 FR 2205333A1
- Authority
- FR
- France
- Prior art keywords
- phenanthridone
- retion
- gastric
- inhibitors
- sec
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000003699 antiulcer agent Substances 0.000 title 1
- 239000002731 stomach secretion inhibitor Substances 0.000 title 1
- WGLPBDUCMAPZCE-UHFFFAOYSA-N Trioxochromium Chemical compound O=[Cr](=O)=O WGLPBDUCMAPZCE-UHFFFAOYSA-N 0.000 abstract 2
- XHXFXVLFKHQFAL-UHFFFAOYSA-N phosphoryl trichloride Chemical compound ClP(Cl)(Cl)=O XHXFXVLFKHQFAL-UHFFFAOYSA-N 0.000 abstract 2
- 229910019213 POCl3 Inorganic materials 0.000 abstract 1
- 125000000218 acetic acid group Chemical group C(C)(=O)* 0.000 abstract 1
- 230000000397 acetylating effect Effects 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- OWYYXVKLNDBOGA-UHFFFAOYSA-N methyl 3-amino-4-phenylbenzoate Chemical class NC1=CC(C(=O)OC)=CC=C1C1=CC=CC=C1 OWYYXVKLNDBOGA-UHFFFAOYSA-N 0.000 abstract 1
- MJEVRGLXKDWWSL-UHFFFAOYSA-N methyl 6-methylphenanthridine-3-carboxylate Chemical class C1=CC=C2C3=CC=C(C(=O)OC)C=C3N=C(C)C2=C1 MJEVRGLXKDWWSL-UHFFFAOYSA-N 0.000 abstract 1
- RZFVLEJOHSLEFR-UHFFFAOYSA-N phenanthridone Chemical class C1=CC=C2C(O)=NC3=CC=CC=C3C2=C1 RZFVLEJOHSLEFR-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/06—Ring systems of three rings
- C07D221/10—Aza-phenanthrenes
- C07D221/12—Phenanthridines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
- C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
- C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
- C07C2603/18—Fluorenes; Hydrogenated fluorenes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT3131972 | 1972-11-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FR2205333A1 true FR2205333A1 (en) | 1974-05-31 |
Family
ID=11233456
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7339363A Withdrawn FR2205333A1 (en) | 1972-11-06 | 1973-11-06 | 6-Phenanthridone-3-carboxylic or-acetic acids - useful as gastric sec-retion inhibitors and anti-ulcer agents |
Country Status (7)
| Country | Link |
|---|---|
| JP (1) | JPS49133376A (enrdf_load_html_response) |
| BE (1) | BE806984A (enrdf_load_html_response) |
| DE (1) | DE2355084A1 (enrdf_load_html_response) |
| FR (1) | FR2205333A1 (enrdf_load_html_response) |
| IL (1) | IL44001A0 (enrdf_load_html_response) |
| NL (1) | NL7315191A (enrdf_load_html_response) |
| ZA (1) | ZA738479B (enrdf_load_html_response) |
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999011624A1 (en) * | 1997-09-03 | 1999-03-11 | Guilford Pharmaceuticals Inc. | Oxo-substituted compounds, process of making, and compositions and methods for inhibiting parp activity |
| US6306889B1 (en) | 1997-09-03 | 2001-10-23 | Guilford Pharmaceuticals Inc. | Compounds, methods and pharmaceutical compositions for treating neural or cardiovascular tissue damage |
| US6348475B1 (en) | 2000-06-01 | 2002-02-19 | Guilford Pharmaceuticals Inc. | Methods, compounds and compositions for treating gout |
| US6380211B1 (en) | 1997-09-03 | 2002-04-30 | Guilford Pharmaceutical Inc. | Alkoxy-substituted compounds, methods, and compositions for inhibiting PARP activity |
| US6387902B1 (en) | 1998-12-31 | 2002-05-14 | Guilford Pharmaceuticals, Inc. | Phenazine compounds, methods and pharmaceutical compositions for inhibiting PARP |
| US6395749B1 (en) | 1998-05-15 | 2002-05-28 | Guilford Pharmaceuticals Inc. | Carboxamide compounds, methods, and compositions for inhibiting PARP activity |
| US6426415B1 (en) | 1997-09-03 | 2002-07-30 | Guilford Pharmaceuticals Inc. | Alkoxy-substituted compounds, methods and compositions for inhibiting parp activity |
| US6514983B1 (en) | 1997-09-03 | 2003-02-04 | Guilford Pharmaceuticals Inc. | Compounds, methods and pharmaceutical compositions for treating neural or cardiovascular tissue damage |
| US6635642B1 (en) | 1997-09-03 | 2003-10-21 | Guilford Pharmaceuticals Inc. | PARP inhibitors, pharmaceutical compositions comprising same, and methods of using same |
| US6716828B1 (en) | 1999-09-01 | 2004-04-06 | Guilford Pharmaceuticals, Inc. | Compounds, methods and pharmaceutical compositions for treating cellular damage, such as neural or cardiovascular tissue damage |
| US6723733B2 (en) | 2000-05-19 | 2004-04-20 | Guilford Pharmaceuticals, Inc. | Sulfonamide and carbamide derivatives of 6(5H)phenanthridinones and their uses |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0089426B1 (en) * | 1979-07-12 | 1986-06-11 | A.H. Robins Company, Incorporated | 2-amino-6-biphenylacetic acids |
| CA2546657C (en) * | 2003-12-05 | 2013-05-14 | Janssen Pharmaceutica N.V. | 6-substituted 2-quinolinones and 2-quinoxalinones as poly(adp-ribose) polymerase inhibitors |
| EP2061765B1 (en) * | 2006-09-01 | 2014-10-22 | Senhwa Biosciences, Inc. | Serine-threonine protein kinase and PARP modulators |
-
1973
- 1973-11-03 DE DE19732355084 patent/DE2355084A1/de active Pending
- 1973-11-05 ZA ZA738479A patent/ZA738479B/xx unknown
- 1973-11-06 FR FR7339363A patent/FR2205333A1/fr not_active Withdrawn
- 1973-11-06 NL NL7315191A patent/NL7315191A/xx unknown
- 1973-11-06 JP JP48125242A patent/JPS49133376A/ja active Pending
- 1973-11-06 BE BE137466A patent/BE806984A/xx unknown
-
1974
- 1974-01-14 IL IL44001A patent/IL44001A0/xx unknown
Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6426415B1 (en) | 1997-09-03 | 2002-07-30 | Guilford Pharmaceuticals Inc. | Alkoxy-substituted compounds, methods and compositions for inhibiting parp activity |
| US6306889B1 (en) | 1997-09-03 | 2001-10-23 | Guilford Pharmaceuticals Inc. | Compounds, methods and pharmaceutical compositions for treating neural or cardiovascular tissue damage |
| US6346536B1 (en) | 1997-09-03 | 2002-02-12 | Guilford Pharmaceuticals Inc. | Poly(ADP-ribose) polymerase inhibitors and method for treating neural or cardiovascular tissue damage using the same |
| US6635642B1 (en) | 1997-09-03 | 2003-10-21 | Guilford Pharmaceuticals Inc. | PARP inhibitors, pharmaceutical compositions comprising same, and methods of using same |
| US6380211B1 (en) | 1997-09-03 | 2002-04-30 | Guilford Pharmaceutical Inc. | Alkoxy-substituted compounds, methods, and compositions for inhibiting PARP activity |
| US6514983B1 (en) | 1997-09-03 | 2003-02-04 | Guilford Pharmaceuticals Inc. | Compounds, methods and pharmaceutical compositions for treating neural or cardiovascular tissue damage |
| WO1999011624A1 (en) * | 1997-09-03 | 1999-03-11 | Guilford Pharmaceuticals Inc. | Oxo-substituted compounds, process of making, and compositions and methods for inhibiting parp activity |
| US6395749B1 (en) | 1998-05-15 | 2002-05-28 | Guilford Pharmaceuticals Inc. | Carboxamide compounds, methods, and compositions for inhibiting PARP activity |
| US6387902B1 (en) | 1998-12-31 | 2002-05-14 | Guilford Pharmaceuticals, Inc. | Phenazine compounds, methods and pharmaceutical compositions for inhibiting PARP |
| US6716828B1 (en) | 1999-09-01 | 2004-04-06 | Guilford Pharmaceuticals, Inc. | Compounds, methods and pharmaceutical compositions for treating cellular damage, such as neural or cardiovascular tissue damage |
| US7307080B2 (en) | 1999-09-01 | 2007-12-11 | Mgi Gp, Inc. | Compounds, methods and pharmaceutical compositions for treating cellular damage, such as neural or cardiovascular tissue damage |
| US6723733B2 (en) | 2000-05-19 | 2004-04-20 | Guilford Pharmaceuticals, Inc. | Sulfonamide and carbamide derivatives of 6(5H)phenanthridinones and their uses |
| US6348475B1 (en) | 2000-06-01 | 2002-02-19 | Guilford Pharmaceuticals Inc. | Methods, compounds and compositions for treating gout |
Also Published As
| Publication number | Publication date |
|---|---|
| ZA738479B (en) | 1974-11-27 |
| NL7315191A (enrdf_load_html_response) | 1974-05-08 |
| IL44001A0 (en) | 1974-05-16 |
| JPS49133376A (enrdf_load_html_response) | 1974-12-21 |
| BE806984A (fr) | 1974-03-01 |
| DE2355084A1 (de) | 1974-05-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |