FR2189048A1 - - Google Patents
Info
- Publication number
- FR2189048A1 FR2189048A1 FR7322116A FR7322116A FR2189048A1 FR 2189048 A1 FR2189048 A1 FR 2189048A1 FR 7322116 A FR7322116 A FR 7322116A FR 7322116 A FR7322116 A FR 7322116A FR 2189048 A1 FR2189048 A1 FR 2189048A1
- Authority
- FR
- France
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D267/02—Seven-membered rings
- C07D267/08—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D267/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D267/14—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
- C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D267/22—Eight-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D281/02—Seven-membered rings
- C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D281/18—Eight-membered rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26376672A | 1972-06-09 | 1972-06-09 | |
| US357528A US3914421A (en) | 1972-06-19 | 1973-05-07 | Pyridopyrrolobenzheterocycles for combatting depression |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2189048A1 true FR2189048A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1974-01-25 |
| FR2189048B1 FR2189048B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1976-10-22 |
Family
ID=26950035
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7322116A Expired FR2189048B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1972-06-19 | 1973-06-18 |
Country Status (7)
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2428035A1 (fr) * | 1978-06-05 | 1980-01-04 | Sankyo Co | Derives de benzothiazocine et de benzothiazonine, et leur application therapeutique |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4013652A (en) * | 1972-06-19 | 1977-03-22 | Endo Laboratories, Inc. | Pyridopyrrolobenzoxazine |
| US4115577A (en) * | 1972-06-19 | 1978-09-19 | Endo Laboratories, Inc. | Pyridopyrrolobenzheterocycles |
| US4183936A (en) * | 1972-06-19 | 1980-01-15 | Endo Laboratories, Inc. | Pyridopyrrolobenzheterocycles |
| US4219550A (en) * | 1978-11-09 | 1980-08-26 | E. I. Du Pont De Nemours And Company | Cis- and trans- octahydropyridopyrrolobenzheterocycles |
| US4997831A (en) * | 1988-09-01 | 1991-03-05 | Glaxo Group Limited | Lactam derivatives |
| US5223625A (en) * | 1988-12-22 | 1993-06-29 | Duphar International Research B.V. | Annelated indolo [3,2,-C]lactams |
| EP0380155A1 (en) * | 1989-01-19 | 1990-08-01 | Duphar International Research B.V | 8,9-Annelated-1,2,3,4-tetrahydro-beta-carboline derivatives |
| US6713471B1 (en) * | 1999-06-15 | 2004-03-30 | Bristol-Myers Squibb Pharma Company | Substituted heterocycle fused gamma-carbolines |
| JP4916633B2 (ja) | 1999-06-15 | 2012-04-18 | ブリストル−マイヤーズ スクイブ ファーマ カンパニー | 置換複素環縮合ガンマ−カルボリン |
| US7071186B2 (en) | 1999-06-15 | 2006-07-04 | Bristol-Myers Squibb Pharma Co. | Substituted heterocycle fused gamma-carbolines |
| CA2432185C (en) * | 2000-12-20 | 2011-11-08 | Bristol-Myers Squibb Company | Substituted pyridoindoles as serotonin agonists and antagonists |
| US6849619B2 (en) * | 2000-12-20 | 2005-02-01 | Bristol-Myers Squibb Company | Substituted pyridoindoles as serotonin agonists and antagonists |
| AU2002248216B2 (en) | 2000-12-20 | 2007-03-01 | Bristol-Myers Squibb Pharma Company | Pyrazinoquinoxaline derivatives as serotonin agonists and antagonists |
| RU2003121306A (ru) | 2000-12-20 | 2005-03-10 | Бристол-Маерс Сквибб Компани (Us) Бристол-Маерс Сквибб Компани (Us) | Замещенные пирролохинолины и пиридохинолины в качестве агонистов и антагонистов серотонина |
| EP1429776A2 (en) * | 2001-09-21 | 2004-06-23 | PHARMACIA & UPJOHN COMPANY | Tricyclic indole derivatives as 5-ht ligands |
| JP4486505B2 (ja) * | 2002-12-19 | 2010-06-23 | ブリストル−マイヤーズ スクイブ カンパニー | セロトニン・レセプタ作用薬および拮抗薬としての置換トリ環式ガンマ−カルボリン化合物 |
| DK2134710T3 (da) | 2007-03-12 | 2020-05-18 | Intra Cellular Therapies Inc | Syntese af gamma-carboliner, der er kondenseret med substitueret heterocyklus |
| WO2011044134A1 (en) | 2009-10-05 | 2011-04-14 | Albany Molecular Research, Inc. | Epiminocycloalkyl(b)indole derivatives as serotonin sub-type 6 (5-ht6) modulators and uses thereof |
| CA2823955A1 (en) | 2011-01-19 | 2012-07-26 | Albany Molecular Research, Inc. | Benzofuro[3,2-c] pyridines and related analogs as serotonin sub-type 6 (5-ht6) modulators for the treatment of obesity, metabolic syndrome, cognition and schizophrenia |
| CN104519886B (zh) | 2012-04-14 | 2017-09-12 | 细胞内治疗公司 | 有机化合物 |
| HUE053159T2 (hu) | 2013-03-15 | 2021-06-28 | Intra Cellular Therapies Inc | Szerves vegyületek |
| CN114366741A (zh) * | 2013-12-03 | 2022-04-19 | 细胞内治疗公司 | 新方法 |
| CA2944755A1 (en) | 2014-04-04 | 2015-10-08 | Intra-Cellular Therapies, Inc. | Organic compounds |
| EP3125893B1 (en) | 2014-04-04 | 2023-09-20 | Intra-Cellular Therapies, Inc. | Deuterated heterocycle fused gamma-carbolines as antagonists of 5-ht2a receptors |
| HUE053737T2 (hu) | 2016-01-26 | 2021-07-28 | Intra Cellular Therapies Inc | Piridopirrolokinoxalin vegyületek, készítményeik és alkalmazásaik |
| IL304192B2 (en) | 2016-03-25 | 2024-12-01 | Intra Cellular Therapies Inc | Deuterated lumateparone for use in treatment of bipolar disorder or bipolar depression |
| US10654854B2 (en) | 2016-03-28 | 2020-05-19 | Intra-Cellular Therapies, Inc. | Salts and crystals of ITI-007 |
| JP6997718B2 (ja) | 2016-03-28 | 2022-01-18 | イントラ－セルラー・セラピーズ・インコーポレイテッド | 新規共結晶 |
| US10682354B2 (en) | 2016-03-28 | 2020-06-16 | Intra-Cellular Therapies, Inc. | Compositions and methods |
| EP3525763B1 (en) | 2016-10-12 | 2025-03-05 | Intra-Cellular Therapies, Inc. | Amorphous solid dispersions |
| US10961245B2 (en) | 2016-12-29 | 2021-03-30 | Intra-Cellular Therapies, Inc. | Substituted heterocycle fused gamma-carbolines for treatment of central nervous system disorders |
| JP6987868B2 (ja) | 2016-12-29 | 2022-01-05 | イントラ−セルラー・セラピーズ・インコーポレイテッドIntra−Cellular Therapies, Inc. | 有機化合物 |
| KR102708440B1 (ko) | 2017-03-24 | 2024-09-20 | 인트라-셀룰라 써래피스, 인코퍼레이티드. | 신규한 조성물 및 방법 |
| US11427587B2 (en) | 2017-07-26 | 2022-08-30 | Intra-Cellular Therapies, Inc. | Organic compounds |
| WO2019023062A1 (en) | 2017-07-26 | 2019-01-31 | Intra-Cellular Therapies, Inc. | ORGANIC COMPOUNDS |
| CA3094949A1 (en) | 2018-03-23 | 2019-09-26 | Intra-Cellular Therapies, Inc. | Deuterated heterocycle fused gamma-carbolines |
| EP3628007B1 (en) | 2018-06-06 | 2023-05-03 | Intra-Cellular Therapies, Inc. | Novel salts and crystals |
| EP3801527B1 (en) | 2018-06-08 | 2025-02-19 | Intra-Cellular Therapies, Inc. | Fused gamma-carbolines for acute treatment of anxiety or depression |
| IL279592B2 (en) | 2018-06-11 | 2025-03-01 | Intra Cellular Therapies Inc | Substituted heterocycle fused gamma-carbolines synthesis |
| WO2020047241A1 (en) | 2018-08-29 | 2020-03-05 | Intra-Cellular Therapies, Inc. | Novel compositions and methods |
| US11957791B2 (en) | 2018-08-31 | 2024-04-16 | Intra-Cellular Therapies, Inc. | Methods |
| CA3108558A1 (en) | 2018-08-31 | 2020-03-05 | Intra-Cellular Therapies, Inc. | Novel methods |
| JP7673040B2 (ja) | 2019-07-07 | 2025-05-08 | イントラ－セルラー・セラピーズ・インコーポレイテッド | 新規方法 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH307223A (de) * | 1952-04-28 | 1955-05-15 | Bayer Ag | Verfahren zur Herstellung eines Derivates des Tetrahydro-y-carbolins. |
-
1973
- 1973-05-07 US US357528A patent/US3914421A/en not_active Expired - Lifetime
- 1973-06-04 IL IL42430A patent/IL42430A0/xx unknown
- 1973-06-16 DE DE2330719A patent/DE2330719A1/de active Pending
- 1973-06-18 FR FR7322116A patent/FR2189048B1/fr not_active Expired
- 1973-06-19 BE BE132425A patent/BE801108A/xx unknown
- 1973-06-19 LU LU67815A patent/LU67815A1/xx unknown
- 1973-06-19 NL NL7308525A patent/NL7308525A/xx unknown
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH307223A (de) * | 1952-04-28 | 1955-05-15 | Bayer Ag | Verfahren zur Herstellung eines Derivates des Tetrahydro-y-carbolins. |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2428035A1 (fr) * | 1978-06-05 | 1980-01-04 | Sankyo Co | Derives de benzothiazocine et de benzothiazonine, et leur application therapeutique |
Also Published As
| Publication number | Publication date |
|---|---|
| BE801108A (fr) | 1973-10-15 |
| FR2189048B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1976-10-22 |
| DE2330719A1 (de) | 1974-01-10 |
| NL7308525A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1973-12-21 |
| LU67815A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1973-09-26 |
| US3914421A (en) | 1975-10-21 |
| IL42430A0 (en) | 1973-08-29 |
Similar Documents
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |