FR2185400A1 - 1-Pyrrolidinocarbonylmethyl-4-acrylamido piperazines - with antiinflam-matory, analgesic, hypotensive, vasodilator, anticholinergic and respiratory analeptic activity - Google Patents
1-Pyrrolidinocarbonylmethyl-4-acrylamido piperazines - with antiinflam-matory, analgesic, hypotensive, vasodilator, anticholinergic and respiratory analeptic activityInfo
- Publication number
- FR2185400A1 FR2185400A1 FR7218690A FR7218690A FR2185400A1 FR 2185400 A1 FR2185400 A1 FR 2185400A1 FR 7218690 A FR7218690 A FR 7218690A FR 7218690 A FR7218690 A FR 7218690A FR 2185400 A1 FR2185400 A1 FR 2185400A1
- Authority
- FR
- France
- Prior art keywords
- antiinflam
- pyrrolidinocarbonylmethyl
- matory
- piperazines
- anticholinergic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 208000001953 Hypotension Diseases 0.000 title 1
- AVPXVFCFEQNCKF-UHFFFAOYSA-N N-[4-(2-oxo-2-pyrrolidin-1-ylethyl)piperazin-1-yl]prop-2-enamide Chemical class N1(CCCC1)C(=O)CN1CCN(CC1)NC(C=C)=O AVPXVFCFEQNCKF-UHFFFAOYSA-N 0.000 title 1
- 230000003555 analeptic effect Effects 0.000 title 1
- 230000000202 analgesic effect Effects 0.000 title 1
- 230000001078 anti-cholinergic effect Effects 0.000 title 1
- 230000003110 anti-inflammatory effect Effects 0.000 title 1
- 208000021822 hypotensive Diseases 0.000 title 1
- 230000001077 hypotensive effect Effects 0.000 title 1
- 230000000241 respiratory effect Effects 0.000 title 1
- 229940124549 vasodilator Drugs 0.000 title 1
- 239000003071 vasodilator agent Substances 0.000 title 1
- XLTVAYSTUZJPQQ-UHFFFAOYSA-N 2-(4-aminopiperazin-1-yl)-1-pyrrolidin-1-ylethanone Chemical compound C1CN(N)CCN1CC(=O)N1CCCC1 XLTVAYSTUZJPQQ-UHFFFAOYSA-N 0.000 abstract 1
- HFBMWMNUJJDEQZ-UHFFFAOYSA-N acryloyl chloride Chemical class ClC(=O)C=C HFBMWMNUJJDEQZ-UHFFFAOYSA-N 0.000 abstract 1
- 125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 abstract 1
- 125000002541 furyl group Chemical group 0.000 abstract 1
- 150000002688 maleic acid derivatives Chemical class 0.000 abstract 1
- 125000001624 naphthyl group Chemical group 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
- 239000000829 suppository Substances 0.000 abstract 1
- 125000001544 thienyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7218690A FR2185400A1 (en) | 1972-05-25 | 1972-05-25 | 1-Pyrrolidinocarbonylmethyl-4-acrylamido piperazines - with antiinflam-matory, analgesic, hypotensive, vasodilator, anticholinergic and respiratory analeptic activity |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7218690A FR2185400A1 (en) | 1972-05-25 | 1972-05-25 | 1-Pyrrolidinocarbonylmethyl-4-acrylamido piperazines - with antiinflam-matory, analgesic, hypotensive, vasodilator, anticholinergic and respiratory analeptic activity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2185400A1 true FR2185400A1 (en) | 1974-01-04 |
| FR2185400B1 FR2185400B1 (enExample) | 1975-06-20 |
Family
ID=9099100
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7218690A Granted FR2185400A1 (en) | 1972-05-25 | 1972-05-25 | 1-Pyrrolidinocarbonylmethyl-4-acrylamido piperazines - with antiinflam-matory, analgesic, hypotensive, vasodilator, anticholinergic and respiratory analeptic activity |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2185400A1 (enExample) |
-
1972
- 1972-05-25 FR FR7218690A patent/FR2185400A1/fr active Granted
Non-Patent Citations (1)
| Title |
|---|
| NEANT * |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2185400B1 (enExample) | 1975-06-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |