FR2244501A1 - 5-Chloro-3-formyl-2-methylindoles - with diuretic analgesic and antiinflammatory activity - Google Patents
5-Chloro-3-formyl-2-methylindoles - with diuretic analgesic and antiinflammatory activityInfo
- Publication number
- FR2244501A1 FR2244501A1 FR7327805A FR7327805A FR2244501A1 FR 2244501 A1 FR2244501 A1 FR 2244501A1 FR 7327805 A FR7327805 A FR 7327805A FR 7327805 A FR7327805 A FR 7327805A FR 2244501 A1 FR2244501 A1 FR 2244501A1
- Authority
- FR
- France
- Prior art keywords
- methylindoles
- diuretic
- analgesic
- chloro
- formyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000000202 analgesic effect Effects 0.000 title abstract 2
- 239000002934 diuretic Substances 0.000 title abstract 2
- 230000001882 diuretic effect Effects 0.000 title abstract 2
- BZODTNGMGUKGEV-UHFFFAOYSA-N 5-chloro-2-methyl-1h-indole-3-carbaldehyde Chemical class C1=C(Cl)C=C2C(C=O)=C(C)NC2=C1 BZODTNGMGUKGEV-UHFFFAOYSA-N 0.000 title 1
- 230000003110 anti-inflammatory effect Effects 0.000 title 1
- WUVWAXJXPRYUME-UHFFFAOYSA-N 5-chloro-2-methyl-1h-indole Chemical class ClC1=CC=C2NC(C)=CC2=C1 WUVWAXJXPRYUME-UHFFFAOYSA-N 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 239000000730 antalgic agent Substances 0.000 abstract 1
- 239000002260 anti-inflammatory agent Substances 0.000 abstract 1
- 229940121363 anti-inflammatory agent Drugs 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 238000011200 topical administration Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/12—Radicals substituted by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
5-Chloro-2-methylindoles of formula: (where X is oxygen, the group N.OR. where R is H, acyl, or opt. substd. benzoyl) have diuretic, analgesic and antiinflammatory agents for oral parenteral, rectal and topical administration; adult dose is 100 mg to 1 g daily.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7327805A FR2244501A1 (en) | 1973-07-30 | 1973-07-30 | 5-Chloro-3-formyl-2-methylindoles - with diuretic analgesic and antiinflammatory activity |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7327805A FR2244501A1 (en) | 1973-07-30 | 1973-07-30 | 5-Chloro-3-formyl-2-methylindoles - with diuretic analgesic and antiinflammatory activity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2244501A1 true FR2244501A1 (en) | 1975-04-18 |
| FR2244501B1 FR2244501B1 (en) | 1977-07-01 |
Family
ID=9123323
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7327805A Granted FR2244501A1 (en) | 1973-07-30 | 1973-07-30 | 5-Chloro-3-formyl-2-methylindoles - with diuretic analgesic and antiinflammatory activity |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2244501A1 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3127898A4 (en) * | 2014-04-04 | 2017-11-08 | Adeka Corporation | Oxime ester compound and photopolymerization initiator containing said compound |
-
1973
- 1973-07-30 FR FR7327805A patent/FR2244501A1/en active Granted
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3127898A4 (en) * | 2014-04-04 | 2017-11-08 | Adeka Corporation | Oxime ester compound and photopolymerization initiator containing said compound |
| US10189847B2 (en) | 2014-04-04 | 2019-01-29 | Adeka Corporation | Oxime ester compound and photopolymerization initiator containing said compound |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2244501B1 (en) | 1977-07-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |