FR2185400A1 - 1-Pyrrolidinocarbonylmethyl-4-acrylamido piperazines - with antiinflam-matory, analgesic, hypotensive, vasodilator, anticholinergic and respiratory analeptic activity - Google Patents

1-Pyrrolidinocarbonylmethyl-4-acrylamido piperazines - with antiinflam-matory, analgesic, hypotensive, vasodilator, anticholinergic and respiratory analeptic activity

Info

Publication number
FR2185400A1
FR2185400A1 FR7218690A FR7218690A FR2185400A1 FR 2185400 A1 FR2185400 A1 FR 2185400A1 FR 7218690 A FR7218690 A FR 7218690A FR 7218690 A FR7218690 A FR 7218690A FR 2185400 A1 FR2185400 A1 FR 2185400A1
Authority
FR
France
Prior art keywords
antiinflam
pyrrolidinocarbonylmethyl
matory
piperazines
anticholinergic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7218690A
Other languages
French (fr)
Other versions
FR2185400B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Delalande SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Delalande SA filed Critical Delalande SA
Priority to FR7218690A priority Critical patent/FR2185400A1/en
Publication of FR2185400A1 publication Critical patent/FR2185400A1/en
Application granted granted Critical
Publication of FR2185400B1 publication Critical patent/FR2185400B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Title cpds. and their maleates, having the formula: where R is thienyl, furyl, pyridyl, naphthyl, cyclohexyl are used at a dosage of 50-400 mg orally 1-5 times daily; 5-100 parenterally once or twice daily; or as suppositories contg. 50-250 mg, once or twice dialy. Prepd. by reaction of acrylic acid chlorides with 1-amino-4-pyrrolidinocarbonylmethylpiperazine.
FR7218690A 1972-05-25 1972-05-25 1-Pyrrolidinocarbonylmethyl-4-acrylamido piperazines - with antiinflam-matory, analgesic, hypotensive, vasodilator, anticholinergic and respiratory analeptic activity Granted FR2185400A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7218690A FR2185400A1 (en) 1972-05-25 1972-05-25 1-Pyrrolidinocarbonylmethyl-4-acrylamido piperazines - with antiinflam-matory, analgesic, hypotensive, vasodilator, anticholinergic and respiratory analeptic activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7218690A FR2185400A1 (en) 1972-05-25 1972-05-25 1-Pyrrolidinocarbonylmethyl-4-acrylamido piperazines - with antiinflam-matory, analgesic, hypotensive, vasodilator, anticholinergic and respiratory analeptic activity

Publications (2)

Publication Number Publication Date
FR2185400A1 true FR2185400A1 (en) 1974-01-04
FR2185400B1 FR2185400B1 (en) 1975-06-20

Family

ID=9099100

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7218690A Granted FR2185400A1 (en) 1972-05-25 1972-05-25 1-Pyrrolidinocarbonylmethyl-4-acrylamido piperazines - with antiinflam-matory, analgesic, hypotensive, vasodilator, anticholinergic and respiratory analeptic activity

Country Status (1)

Country Link
FR (1) FR2185400A1 (en)

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NEANT *

Also Published As

Publication number Publication date
FR2185400B1 (en) 1975-06-20

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Legal Events

Date Code Title Description
ST Notification of lapse