FR2182914A1 - - Google Patents

Info

Publication number
FR2182914A1
FR2182914A1 FR7311419A FR7311419A FR2182914A1 FR 2182914 A1 FR2182914 A1 FR 2182914A1 FR 7311419 A FR7311419 A FR 7311419A FR 7311419 A FR7311419 A FR 7311419A FR 2182914 A1 FR2182914 A1 FR 2182914A1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7311419A
Other versions
FR2182914B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kyorin Pharmaceutical Co Ltd
Original Assignee
Kyorin Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyorin Pharmaceutical Co Ltd filed Critical Kyorin Pharmaceutical Co Ltd
Publication of FR2182914A1 publication Critical patent/FR2182914A1/fr
Application granted granted Critical
Publication of FR2182914B1 publication Critical patent/FR2182914B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
FR7311419A 1972-03-30 1973-03-29 Expired FR2182914B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP47032033A JPS5229318B2 (fr) 1972-03-30 1972-03-30

Publications (2)

Publication Number Publication Date
FR2182914A1 true FR2182914A1 (fr) 1973-12-14
FR2182914B1 FR2182914B1 (fr) 1976-05-14

Family

ID=12347544

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7311419A Expired FR2182914B1 (fr) 1972-03-30 1973-03-29

Country Status (12)

Country Link
US (1) US3850941A (fr)
JP (1) JPS5229318B2 (fr)
AR (1) AR197709A1 (fr)
BE (1) BE797554A (fr)
BR (1) BR7302268D0 (fr)
CA (1) CA989843A (fr)
DE (1) DE2315801C3 (fr)
ES (1) ES413188A1 (fr)
FR (1) FR2182914B1 (fr)
GB (1) GB1378375A (fr)
HU (1) HU167305B (fr)
SE (1) SE402592B (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2289192A1 (fr) * 1974-11-01 1976-05-28 Kyorin Seiyaku Kk Pyrazolo(1,5-a)pyridines et medicament contenant ces substances
EP0215438A2 (fr) * 1985-09-14 1987-03-25 Kyorin Seiyaku Kabushiki Kaisha Utilisation de la 3-isobutyryl-2-isopropylpyrazolo[1,5-a]pyridine pour préparer un médicament antirhumatismal
EP0319902A3 (en) * 1987-12-10 1990-01-31 Kyorin Seiyaku Kabushiki Kaisha Transdermal absorptive drug formulation
EP0355234A1 (fr) * 1988-08-25 1990-02-28 Merrell Dow Pharmaceuticals Inc. Dérivés de la pyrazolo-pyridine avec activité antiethérosclérotique et hypecholesthérolémique

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4097483A (en) * 1974-11-01 1978-06-27 Kyorin Pharmaceutical Co., Ltd. Pyrazolo 1,5-a!pyridines
US4237300A (en) * 1975-12-09 1980-12-02 Merck & Co., Inc. Certain 6-substituted-2-pyridinamines
JPS5968553A (ja) * 1982-10-13 1984-04-18 Automob Antipollut & Saf Res Center 燃料タンク内蔵式燃料ポンプ
JPS6072975U (ja) * 1983-10-26 1985-05-22 ヤンマーディーゼル株式会社 燃料ポンプのエア抜き装置
JPH0621066B2 (ja) * 1984-03-14 1994-03-23 杏林製薬株式会社 ３―イソブチリル―２―イソプロピルピラゾロ〔１，５―ａ〕ピリジンの徐放性医薬品組成物
US4925849A (en) * 1987-06-15 1990-05-15 Fujisawa Pharmaceutical Company, Ltd. Pharmaceutically useful pyrazolopyridines
JPH085790B2 (ja) * 1988-11-11 1996-01-24 杏林製薬株式会社 記憶障害改善薬
JPH0256853U (fr) * 1989-10-04 1990-04-24
JPH06166687A (ja) * 1990-07-18 1994-06-14 Senju Pharmaceut Co Ltd ピラゾロ〔１，５−ａ〕ピリジン化合物、その製造法および用途
JP5038568B2 (ja) 1999-08-21 2012-10-03 ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング 協力剤の組合せ物
AP2005003232A0 (en) 2002-08-19 2005-03-31 Pfizer Prod Inc Combination therapy for hyperproliferative diseases.
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
BRPI0409229A (pt) 2003-04-01 2006-03-28 Applied Research Systems inibidores das fosfodiesterases na infertilidade
GEP20084406B (en) 2003-05-30 2008-06-25 Ranbaxy Lab Ltd Substituted pyrrole derivatives and their use as hmg-co inhibitors
TW200517114A (en) 2003-10-15 2005-06-01 Combinatorx Inc Methods and reagents for the treatment of immunoinflammatory disorders
DE602004031356D1 (de) 2003-11-21 2011-03-24 Zalicus Inc Verfahren und reagenzien zur behandlung von entzündlichen erkrankungen
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
AU2006313430B2 (en) 2005-11-08 2012-09-06 Ranbaxy Laboratories Limited Process for (3R,5R)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4- [(4-hydroxy methyl phenyl amino) carbonyl]-pyrrol-1-yl]-3, 5-dihydroxy-heptanoic acid hemi calcium salt
NZ568694A (en) 2005-11-09 2011-09-30 Zalicus Inc Method, compositions, and kits for the treatment of medical conditions
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
JP5352452B2 (ja) * 2006-06-06 2013-11-27 メディシノバ， インコーポレイテッド 置換ピラゾロ［１，５−ａ］ピリジン化合物およびその使用方法
US8404896B2 (en) 2006-12-01 2013-03-26 Bristol-Myers Squibb Company N-((3-benzyl)-2,2-(bis-phenyl)-propan-1-amine derivatives as CETP inhibitors for the treatment of atherosclerosis and cardiovascular diseases
US20080181876A1 (en) 2007-01-30 2008-07-31 Johnson Kirk W Methods for treating acute and subchronic pain
US7879802B2 (en) 2007-06-04 2011-02-01 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
US7536799B2 (en) * 2007-06-07 2009-05-26 Keson Industries Chalk line apparatus with strategically located chalk fill opening
EP2176260A1 (fr) * 2007-07-11 2010-04-21 Auckland Uniservices Limited Pyrazolo[1,5-a]pyridines et leur utilisation en cancérothérapie
AU2008287421A1 (en) * 2007-08-10 2009-02-19 Glaxosmithkline Llc Nitrogen containing bicyclic chemical entities for treating viral infections
CA2696041A1 (fr) 2007-08-15 2009-02-19 Kyorin Pharmaceutical Co., Ltd. Agent preventif, inhibiteur ou remede pour l'anevrisme cerebral comportant de l'ibudilast en tant qu'ingredient actif
EP3239170B1 (fr) 2008-06-04 2019-03-20 Synergy Pharmaceuticals Inc. Agonistes de guanylate cyclase utile dans le traitement de troubles gastro-intestinaux, d'une inflammation, d'un cancer et d'autres troubles
WO2010005520A2 (fr) * 2008-06-30 2010-01-14 Concert Pharmaceuticals, Inc. Dérivés de 2-alkyl-3-acylpyrazolo[1,5-a]pyridines
EP3241839B1 (fr) 2008-07-16 2019-09-04 Bausch Health Ireland Limited Agonistes de guanylate cyclase utiles pour le traitement de troubles gastro-intestinaux, inflammatoires, cancéreux et autres
WO2010017047A1 (fr) * 2008-08-05 2010-02-11 Merck & Co., Inc. Composés thérapeutiques
WO2010021681A2 (fr) * 2008-08-18 2010-02-25 Combinatorx (Singapore) Pte. Ltd. Compositions et procédés pour le traitement de maladies virales
KR101701943B1 (ko) 2009-11-13 2017-02-02 도레이 카부시키가이샤 당뇨병의 치료 또는 예방약
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
CN108676076A (zh) 2011-03-01 2018-10-19 辛纳吉制药公司 制备鸟苷酸环化酶c激动剂的方法
ES2395801B1 (es) 2011-06-23 2014-06-06 María Carmen PARDINA PALLEJÀ "pentoxifilina por vía transvaginal para el tratamiento de la infertilidad"
CN102617579A (zh) * 2012-03-28 2012-08-01 黑龙江大学 一种异丁司特的制备方法
US9545446B2 (en) 2013-02-25 2017-01-17 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase and their uses
US9708367B2 (en) 2013-03-15 2017-07-18 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase and their uses
CA2905435A1 (fr) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Compositions utiles pour le traitement de troubles gastro-intestinaux
BR112015026513A2 (pt) 2013-04-17 2017-07-25 Pfizer derivados de n-piperidin-3-ilbenzamida para tratar as doenças cardiovasculares
JP6606491B2 (ja) 2013-06-05 2019-11-13 シナジー ファーマシューティカルズ インコーポレイテッド グアニル酸シクラーゼｃの超高純度アゴニスト、その作成および使用方法
IL280864B2 (en) 2013-08-09 2024-03-01 Ardelyx Inc Compounds and methods for inhibiting phosphate transport
WO2016055901A1 (fr) 2014-10-08 2016-04-14 Pfizer Inc. Composés d'amide substitué
CN108033959A (zh) * 2018-01-29 2018-05-15 山东省药学科学院 一种异丁司特的化学合成方法
MX2021008533A (es) 2019-01-18 2021-08-19 Astrazeneca Ab Inhibidores de la pcsk9 y metodos de uso de los mismos.
WO2020237096A1 (fr) 2019-05-21 2020-11-26 Ardelyx, Inc. Combinaison pour baisser le phosphate sérique chez un patient
CN113387947B (zh) * 2021-07-12 2022-07-01 中国科学院成都生物研究所 调节雌激素受体合成活性的吡唑并吡啶衍生物

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2289192A1 (fr) * 1974-11-01 1976-05-28 Kyorin Seiyaku Kk Pyrazolo(1,5-a)pyridines et medicament contenant ces substances
EP0215438A2 (fr) * 1985-09-14 1987-03-25 Kyorin Seiyaku Kabushiki Kaisha Utilisation de la 3-isobutyryl-2-isopropylpyrazolo[1,5-a]pyridine pour préparer un médicament antirhumatismal
EP0215438A3 (en) * 1985-09-14 1989-05-24 Kyorin Seiyaku Kabushiki Kaisha Use of 3-isobutyryl-2-isopropylpyrazoloû1,5-a¨pyridine as an anti-rheumatic agent
EP0319902A3 (en) * 1987-12-10 1990-01-31 Kyorin Seiyaku Kabushiki Kaisha Transdermal absorptive drug formulation
US5602165A (en) * 1987-12-10 1997-02-11 Kyorin Seiyaku Kabushiki Kaisha Transdermal absorptive drug formulation
EP0355234A1 (fr) * 1988-08-25 1990-02-28 Merrell Dow Pharmaceuticals Inc. Dérivés de la pyrazolo-pyridine avec activité antiethérosclérotique et hypecholesthérolémique

Also Published As

Publication number Publication date
AR197709A1 (es) 1974-04-30
FR2182914B1 (fr) 1976-05-14
BE797554A (fr) 1973-07-16
JPS5229318B2 (fr) 1977-08-01
DE2315801B2 (de) 1978-06-22
BR7302268D0 (pt) 1974-08-29
HU167305B (fr) 1975-09-27
ES413188A1 (es) 1976-01-16
DE2315801C3 (de) 1979-02-22
CA989843A (en) 1976-05-25
JPS4897898A (fr) 1973-12-13
AU5376173A (en) 1974-09-26
GB1378375A (en) 1974-12-27
SE402592B (sv) 1978-07-10
US3850941A (en) 1974-11-26
DE2315801A1 (de) 1973-10-11

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