FR2175565A1 - 10-(4-alkoxy-4-alkylpiperidinoalkyl)phenothiazines - - with neuroleptic,antihistaminic,analgesic and spasmolytic activity - Google Patents

10-(4-alkoxy-4-alkylpiperidinoalkyl)phenothiazines - - with neuroleptic,antihistaminic,analgesic and spasmolytic activity

Info

Publication number
FR2175565A1
FR2175565A1 FR7208802A FR7208802A FR2175565A1 FR 2175565 A1 FR2175565 A1 FR 2175565A1 FR 7208802 A FR7208802 A FR 7208802A FR 7208802 A FR7208802 A FR 7208802A FR 2175565 A1 FR2175565 A1 FR 2175565A1
Authority
FR
France
Prior art keywords
alkylpiperidinoalkyl
antihistaminic
neuroleptic
phenothiazines
analgesic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7208802A
Other languages
French (fr)
Other versions
FR2175565B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Priority to FR7208802A priority Critical patent/FR2175565A1/en
Priority to ES412585A priority patent/ES412585A1/en
Publication of FR2175565A1 publication Critical patent/FR2175565A1/en
Application granted granted Critical
Publication of FR2175565B1 publication Critical patent/FR2175565B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/48—Oxygen atoms attached in position 4 having an acyclic carbon atom attached in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

10-(4-Alkoxy-4-alkylpiperidinoalkyl)phenothiazines of formula: and their acid addn salts where X is H, Cl, CF3, -OMe,- -SMe; B, R are H, 1-4C alkyl; Z is 1-10C alkyl, p is 0 or 1; n is 0, 1 or 2; A is H, the group -CO.R' where R' is polymethoxyphenyl or 1-18C alkyl opt. contg. a double bond or interrupted by an O-atom, the group -CO2.R2 where R2 is 1-15C alkyl. The cpds. have neuroleptic, antihistaminic, analgesic, and spasmolytic activity.
FR7208802A 1972-03-14 1972-03-14 10-(4-alkoxy-4-alkylpiperidinoalkyl)phenothiazines - - with neuroleptic,antihistaminic,analgesic and spasmolytic activity Granted FR2175565A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FR7208802A FR2175565A1 (en) 1972-03-14 1972-03-14 10-(4-alkoxy-4-alkylpiperidinoalkyl)phenothiazines - - with neuroleptic,antihistaminic,analgesic and spasmolytic activity
ES412585A ES412585A1 (en) 1972-03-14 1973-03-13 Procedure for the preparation of derivatives of (alcoxy-4-alcohil-4-piperidinoalcohil) -10-phenotyazines. (Machine-translation by Google Translate, not legally binding)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7208802A FR2175565A1 (en) 1972-03-14 1972-03-14 10-(4-alkoxy-4-alkylpiperidinoalkyl)phenothiazines - - with neuroleptic,antihistaminic,analgesic and spasmolytic activity

Publications (2)

Publication Number Publication Date
FR2175565A1 true FR2175565A1 (en) 1973-10-26
FR2175565B1 FR2175565B1 (en) 1975-03-14

Family

ID=9095160

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7208802A Granted FR2175565A1 (en) 1972-03-14 1972-03-14 10-(4-alkoxy-4-alkylpiperidinoalkyl)phenothiazines - - with neuroleptic,antihistaminic,analgesic and spasmolytic activity

Country Status (2)

Country Link
ES (1) ES412585A1 (en)
FR (1) FR2175565A1 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1344593A (en) * 1961-11-25 1963-11-29 Boehringer & Soehne Gmbh Process for the preparation of novel alkoxy-piperidine derivatives and their salts
FR1578731A (en) * 1967-11-24 1969-08-22

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1344593A (en) * 1961-11-25 1963-11-29 Boehringer & Soehne Gmbh Process for the preparation of novel alkoxy-piperidine derivatives and their salts
FR1578731A (en) * 1967-11-24 1969-08-22

Also Published As

Publication number Publication date
ES412585A1 (en) 1976-01-16
FR2175565B1 (en) 1975-03-14

Similar Documents

Publication Publication Date Title
ES453309A1 (en) Bis(2-phenoxyalkane carboxylic acids) and derivatives thereof and their use as medicaments
NO142400C (en) ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE NEW BENZIMIDAZOLINON DERIVATIVES
FR2088019A1 (en) Esters of 2 and 6-substituted nicotinic acids - with vasomotor active
FR2277589A1 (en) AMINO-ALCOHOLS CONTAINING A TRICYCLIC SUBSTITUTE, THEIR NON-TOXIC SALTS AND PROCESS FOR THEIR PREPARATION
FR2175565A1 (en) 10-(4-alkoxy-4-alkylpiperidinoalkyl)phenothiazines - - with neuroleptic,antihistaminic,analgesic and spasmolytic activity
CH283241A (en) Process for the preparation of a new antimalarial derivative of piperazine.
ES432027A1 (en) Pharmacologically active anilinobenzothiazoles
FR2155927A1 (en) 1-phenylcyclo hexane carboxylic acid esters - with antispasmodic and anticholinergic activity
ES345690A1 (en) 2-aminomethyl benzofuran derivatives
FR2166101A1 (en) 1,4-di (morpholino,piperidino or pyrrolidino)-7-substd - -pyrido (3,4-d)-pyridazines - as diuretics
FR2137186A1 (en) Folic acid salts - used as neuro-stimulants and for dynamising muscular function
GB1394756A (en) Pharmaceutically active benzofuran derivatives
FR2231372A1 (en) 2-(3-Aminopropionyl)-benzofuran compns. - for treating spasm and as inhibitors of biosynthesis of uric acid
FR2073427A1 (en) 4-methyl-5-ethyl-n-heterocyclic thiazoles - with antianoxic activity
FR2005291A1 (en) Heterocyclic amines, analgesic, antiinflammatory
FR2143526A1 (en) 3-carboxy-4-salicyloxy-6-sulphamoylquinolines - with analgesic,antiinflammatory, antipyretic, antirheumatic activity
ES385522A1 (en) Azamorphinan compounds
GB1388146A (en) Hydroxycrotonic acid derivatives
FR2092639A1 (en) 10-(1-piperonylpiperazinoalkanoyl) phenothiazines - with specific spasmolytic,antipyretic and antiemetic activity
ES424318A1 (en) 4-{8 N-(2-methyl-3-hydroxy-4-hydroxymethyl-5-pyridylmethyl)-piperazino{9 -p-fluoro-butyrophenone
FR2085651A1 (en) 4-(2-(p-chlorophenoxy)-2-methylpropionyloxymethyloxazolines - with hypolipaemic and hypocholesterolaemic activity
FR2163322A1 (en) Tert aminomethyl pentenyl dioxolanes - vasodilators hypotensives spasmolytics diuretics and analgesics
FR2088020A1 (en) Aminoalkyl esters of diacetylgentisic acid - with analgesic activity
FR2175527A1 (en) N-alkylhyoscines derivs - with spasmolytic activity
FR2192814A1 (en) 2-Isopropyl-5-methyl phenoxy acetamides - with peripheral, cerebral and coronary vasodilatory activity

Legal Events

Date Code Title Description
ST Notification of lapse