FR2092639A1 - 10-(1-piperonylpiperazinoalkanoyl) phenothiazines - with specific spasmolytic,antipyretic and antiemetic activity - Google Patents

10-(1-piperonylpiperazinoalkanoyl) phenothiazines - with specific spasmolytic,antipyretic and antiemetic activity

Info

Publication number
FR2092639A1
FR2092639A1 FR7020381A FR7020381A FR2092639A1 FR 2092639 A1 FR2092639 A1 FR 2092639A1 FR 7020381 A FR7020381 A FR 7020381A FR 7020381 A FR7020381 A FR 7020381A FR 2092639 A1 FR2092639 A1 FR 2092639A1
Authority
FR
France
Prior art keywords
specific
spasmolytic
antipyretic
piperonylpiperazinoalkanoyl
phenothiazines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7020381A
Other languages
French (fr)
Other versions
FR2092639B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to FR7020381A priority Critical patent/FR2092639A1/en
Publication of FR2092639A1 publication Critical patent/FR2092639A1/en
Application granted granted Critical
Publication of FR2092639B1 publication Critical patent/FR2092639B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Cpds. of formula:- (where R is 1-5C alkylene, opt. substd) and their acid-addition salts. The cpds. are spasmolytics with antiemetic and antipyretic activity. They are of low toxicity and have no effect on blood pressure, respiratory rate, CNS or gastric secretion. The spasmolytic activity is a little less than that of atropine, but is long-lasting and is more specific. No mydriatic effect is observed. Prepared by treating phenothiazine with a chloroalkanoyl halide, then condensing the 10-chloroalkanoylphenothiazine with 1-piperonylpiperazine.
FR7020381A 1970-06-03 1970-06-03 10-(1-piperonylpiperazinoalkanoyl) phenothiazines - with specific spasmolytic,antipyretic and antiemetic activity Granted FR2092639A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7020381A FR2092639A1 (en) 1970-06-03 1970-06-03 10-(1-piperonylpiperazinoalkanoyl) phenothiazines - with specific spasmolytic,antipyretic and antiemetic activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7020381A FR2092639A1 (en) 1970-06-03 1970-06-03 10-(1-piperonylpiperazinoalkanoyl) phenothiazines - with specific spasmolytic,antipyretic and antiemetic activity

Publications (2)

Publication Number Publication Date
FR2092639A1 true FR2092639A1 (en) 1972-01-28
FR2092639B1 FR2092639B1 (en) 1973-07-13

Family

ID=9056619

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7020381A Granted FR2092639A1 (en) 1970-06-03 1970-06-03 10-(1-piperonylpiperazinoalkanoyl) phenothiazines - with specific spasmolytic,antipyretic and antiemetic activity

Country Status (1)

Country Link
FR (1) FR2092639A1 (en)

Also Published As

Publication number Publication date
FR2092639B1 (en) 1973-07-13

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Legal Events

Date Code Title Description
TP Transmission of property
TP Transmission of property
GC Lien (pledge) constituted
GR Lien (pledge) cancelled due to a court decision