FR2158263A1 - 1-phenyl-2-cinnamylamino-ethanol derivs - with antidepressant props - Google Patents

1-phenyl-2-cinnamylamino-ethanol derivs - with antidepressant props

Info

Publication number
FR2158263A1
FR2158263A1 FR7237749A FR7237749A FR2158263A1 FR 2158263 A1 FR2158263 A1 FR 2158263A1 FR 7237749 A FR7237749 A FR 7237749A FR 7237749 A FR7237749 A FR 7237749A FR 2158263 A1 FR2158263 A1 FR 2158263A1
Authority
FR
France
Prior art keywords
formula
derivs
cinnamylamino
antidepressant
props
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7237749A
Other languages
English (en)
French (fr)
Other versions
FR2158263B1 (xx
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of FR2158263A1 publication Critical patent/FR2158263A1/fr
Application granted granted Critical
Publication of FR2158263B1 publication Critical patent/FR2158263B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/147—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/02—Acyclic alcohols with carbon-to-carbon double bonds
    • C07C33/025—Acyclic alcohols with carbon-to-carbon double bonds with only one double bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/04—Compounds containing oxirane rings containing only hydrogen and carbon atoms in addition to the ring oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/08—Compounds containing oxirane rings with hydrocarbon radicals, substituted by halogen atoms, nitro radicals or nitroso radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FR7237749A 1971-10-28 1972-10-25 1-phenyl-2-cinnamylamino-ethanol derivs - with antidepressant props Granted FR2158263A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1569971 1971-10-28

Publications (2)

Publication Number Publication Date
FR2158263A1 true FR2158263A1 (en) 1973-06-15
FR2158263B1 FR2158263B1 (xx) 1976-03-05

Family

ID=4411190

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7237749A Granted FR2158263A1 (en) 1971-10-28 1972-10-25 1-phenyl-2-cinnamylamino-ethanol derivs - with antidepressant props

Country Status (8)

Country Link
JP (1) JPS4852732A (xx)
AU (1) AU4822172A (xx)
BE (1) BE790604A (xx)
DD (1) DD99777A5 (xx)
DE (1) DE2252080A1 (xx)
FR (1) FR2158263A1 (xx)
HU (1) HU164671B (xx)
NL (1) NL7214315A (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0103830A3 (de) * 1982-09-22 1985-07-31 Bayer Ag Wachstumsfördernde Phenylethylamin-Derivate
FR2796069B3 (fr) * 1999-07-09 2001-08-24 Sanofi Synthelabo Nouveaux procedes de preparation de derives de 2-(2- arylmorpholin-2-yl)ethanol substitues, enantiomeriquement purs, et composes intermediaires utiles dans ces procedes
WO2012172119A2 (en) * 2012-05-08 2012-12-20 Lonza Ltd Method for the preparation of medetomidine
PL2847173T3 (pl) 2012-05-08 2016-06-30 Lonza Ag Sposób wytwarzania medetomidyny
MY165212A (en) 2012-05-08 2018-03-05 Lonza Ag Method for preparation of 2-(2,3-dimethylphenyl)-1- propanal
DK2867195T3 (en) 2012-06-28 2016-04-04 Lonza Ag PROCESS FOR THE PREPARATION OF 2- (2,3-dimethylphenyl) -1-propanal WITH chloroacetone
ES2565066T3 (es) 2012-06-28 2016-03-31 Lonza Ltd Método para la preparación de medetomidina con cloroacetona
CN106518812A (zh) * 2016-10-25 2017-03-22 湖南大学 一种美托咪定及其中间体的制备方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE609151C (de) * 1930-02-01 1935-02-08 I G Farbenindustrie Akt Ges Verfahren zur Darstellung von Aminoalkoholen mit sekundaerer oder tertiaerer Aminogruppe

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE609151C (de) * 1930-02-01 1935-02-08 I G Farbenindustrie Akt Ges Verfahren zur Darstellung von Aminoalkoholen mit sekundaerer oder tertiaerer Aminogruppe

Also Published As

Publication number Publication date
NL7214315A (xx) 1973-05-02
BE790604A (fr) 1973-04-26
DE2252080A1 (de) 1973-05-03
JPS4852732A (xx) 1973-07-24
DD99777A5 (xx) 1973-08-20
AU4822172A (en) 1974-05-02
HU164671B (xx) 1974-03-28
FR2158263B1 (xx) 1976-03-05

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Legal Events

Date Code Title Description
ST Notification of lapse