FR2125203A1 - 4'-disubstd-amino methyl spiro (dibenzo(ad)c - dioxolan (1,3) - Google Patents
4'-disubstd-amino methyl spiro (dibenzo(ad)c - dioxolan (1,3)Info
- Publication number
- FR2125203A1 FR2125203A1 FR7105662A FR7105662A FR2125203A1 FR 2125203 A1 FR2125203 A1 FR 2125203A1 FR 7105662 A FR7105662 A FR 7105662A FR 7105662 A FR7105662 A FR 7105662A FR 2125203 A1 FR2125203 A1 FR 2125203A1
- Authority
- FR
- France
- Prior art keywords
- dioxolan
- dibenzo
- spiro
- disubstd
- amino methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- -1 pyrrolidino, piperidino, hexamethyleneimino Chemical group 0.000 abstract 3
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 abstract 2
- VZGDMQKNWNREIO-UHFFFAOYSA-N tetrachloromethane Chemical compound ClC(Cl)(Cl)Cl VZGDMQKNWNREIO-UHFFFAOYSA-N 0.000 abstract 2
- WNXJIVFYUVYPPR-UHFFFAOYSA-N 1,3-dioxolane Chemical compound C1COCO1 WNXJIVFYUVYPPR-UHFFFAOYSA-N 0.000 abstract 1
- 229910021627 Tin(IV) chloride Inorganic materials 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 230000001773 anti-convulsant effect Effects 0.000 abstract 1
- 230000001430 anti-depressive effect Effects 0.000 abstract 1
- 230000001387 anti-histamine Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 230000000794 anti-serotonin Effects 0.000 abstract 1
- 239000001961 anticonvulsive agent Substances 0.000 abstract 1
- 229960003965 antiepileptics Drugs 0.000 abstract 1
- 239000000739 antihistaminic agent Substances 0.000 abstract 1
- 239000003420 antiserotonin agent Substances 0.000 abstract 1
- 229940124630 bronchodilator Drugs 0.000 abstract 1
- 239000000812 cholinergic antagonist Substances 0.000 abstract 1
- GKIPXFAANLTWBM-UHFFFAOYSA-N epibromohydrin Chemical compound BrCC1CO1 GKIPXFAANLTWBM-UHFFFAOYSA-N 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
- 125000004573 morpholin-4-yl group Chemical group N1(CCOCC1)* 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 125000000467 secondary amino group Chemical class [H]N([*:1])[*:2] 0.000 abstract 1
- 239000000932 sedative agent Substances 0.000 abstract 1
- 230000001624 sedative effect Effects 0.000 abstract 1
- 230000002048 spasmolytic effect Effects 0.000 abstract 1
- HPGGPRDJHPYFRM-UHFFFAOYSA-J tin(iv) chloride Chemical compound Cl[Sn](Cl)(Cl)Cl HPGGPRDJHPYFRM-UHFFFAOYSA-J 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (15)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7105662A FR2125203A1 (en) | 1971-02-19 | 1971-02-19 | 4'-disubstd-amino methyl spiro (dibenzo(ad)c - dioxolan (1,3) |
| SE7104560A SE377936B (cg-RX-API-DMAC10.html) | 1970-04-15 | 1971-04-07 | |
| CH507271A CH522632A (fr) | 1970-04-15 | 1971-04-07 | Procédé de préparation de nouveaux dérivés de l'amino-méthyl-4'-spiro(dibenzo(a-d)cycloheptadi-(ou tri-)ène-5 : 2'- dioxolane (1',3')) |
| BE765516A BE765516A (fr) | 1970-04-15 | 1971-04-08 | Nouveaux derives de l'aminomethyl-4'spiro (dibenzo (a-d) cycloheptadi- (ou tri-) ene-5:2' -dioxolane (1', 3') ), leur procede de preparation et leur application en therapeutique |
| IL36571A IL36571A (en) | 1970-04-15 | 1971-04-08 | Derivatives of 4'-aminomethyl spiro (dibenzo (a-d)cyclohepta di(tri)ene-5,2'-dioxolane),their preparation and pharmaceutical compositions containing them |
| LU62949D LU62949A1 (cg-RX-API-DMAC10.html) | 1970-04-15 | 1971-04-08 | |
| JP2145171A JPS5323304B1 (cg-RX-API-DMAC10.html) | 1970-04-15 | 1971-04-08 | |
| DE2117358A DE2117358C3 (de) | 1970-04-15 | 1971-04-08 | 4'-Aminomethyl-spiro eckige Klammer auf dibenzo eckige Klammer auf a,d eckige Klammer zu cycloheptadi-(oder tri-) en-5,2'-(1 \3'-dioxolan) eckige Klammer zu -Derivate, Verfahren zu deren Herstellung und diese Verbindungen enthaltene Arzneimittel |
| ES390064A ES390064A1 (es) | 1970-04-15 | 1971-04-08 | Procedimiento de preparacion de derivados de aminometil-4'-espiro (dibenzo (a-d) cicloheptadi-z(o tri) eno-5:2'-dioxo- lano (1',3')). |
| CS7100002531A CS180572B2 (en) | 1970-04-15 | 1971-04-08 | Method of preparing derivatives of 4'-aminomethylspiro/dibenzo/a-d/cycloheptadi-/or tri-/ene-5,2-/1,3'-dioxolane// |
| US00133441A US3726900A (en) | 1970-04-15 | 1971-04-12 | Dibenzo(a-d)cycloheptadi(or tri)ene-5:2'-dioxalanes(i,3') |
| CA110,359*7A CA945157A (en) | 1970-04-15 | 1971-04-14 | Derives de l'aminomethyl-4'spiro (dibenzo (a-d) cycloheptatriene-5:2'-dioxolane (1',3')) leur procede de preparation et leur application en therapeutique |
| SU1647378A SU465788A3 (ru) | 1970-04-15 | 1971-04-15 | "Способ получени производных спиро (дибензо (а- ) -циклогептадиили три) ен-5:2" (4"-аминометилдиоксалана 1"3") |
| NL7105014.A NL161449C (nl) | 1970-04-15 | 1971-04-15 | Werkwijze voor de bereiding van 4-alkylaminomethyl-1,3- dioxolanverbindingen met analgetische werking, werkwijze voor de bereiding van farmaceutische pre- paraten onder toepassing van aldus verkregen verbindin- gen, alsmede gevormde farmaceutische preparaten. |
| GB1295815D GB1295815A (cg-RX-API-DMAC10.html) | 1970-04-15 | 1971-04-19 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7105662A FR2125203A1 (en) | 1971-02-19 | 1971-02-19 | 4'-disubstd-amino methyl spiro (dibenzo(ad)c - dioxolan (1,3) |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2125203A1 true FR2125203A1 (en) | 1972-09-29 |
| FR2125203B1 FR2125203B1 (cg-RX-API-DMAC10.html) | 1974-08-02 |
Family
ID=9072149
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7105662A Granted FR2125203A1 (en) | 1970-04-15 | 1971-02-19 | 4'-disubstd-amino methyl spiro (dibenzo(ad)c - dioxolan (1,3) |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2125203A1 (cg-RX-API-DMAC10.html) |
-
1971
- 1971-02-19 FR FR7105662A patent/FR2125203A1/fr active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| FR2125203B1 (cg-RX-API-DMAC10.html) | 1974-08-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |