JPS577481A - Novel benzopyran derivative - Google Patents
Novel benzopyran derivativeInfo
- Publication number
- JPS577481A JPS577481A JP8084180A JP8084180A JPS577481A JP S577481 A JPS577481 A JP S577481A JP 8084180 A JP8084180 A JP 8084180A JP 8084180 A JP8084180 A JP 8084180A JP S577481 A JPS577481 A JP S577481A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- formula
- agent
- nitrated
- dihydro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
Abstract
NEW MATERIAL:A compound of formula I (P is 3,4-dihydro-2H-1-benzopyran ring; A is direct bond or -O-CH2; B is direct bond, alkylene, etc.; R is H, halogen, lower alkyl,alkoxyl,alkyleneoxy, etc.; R1 and R2 are H, alkyl, hydroxyalkyl, etc.; R3 is H or nitro; m and n are 1 or 2).
EXAMPLE: 3,4-Dihydro-8-[ (2-hydroxy-3-isopropylamino)propoxy ]-3-nitratomethyl- 2H-1-benzopyran.
USE: An antistenocaridiac agent, hypotensive agent, ameliorant of cerebral circulation and antiarrhythmic agent.
PROCESS: A compound of formula II (Q is OH, ethoxycarbonyloxy, acetoxy, etc.) is nitrated and converted into an aminoalkanol derivative thereof to give a compound of formula III. The resultant compound is then nitrated at room temperature to 90°C to afford the compound of formula I.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (20)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP8084180A JPS6054317B2 (en) | 1980-06-17 | 1980-06-17 | New benzopyran derivatives |
US06/271,927 US4394382A (en) | 1980-06-17 | 1981-06-09 | Dihydrobenzopyran compounds and pharmaceutical composition comprising said compounds |
AU71652/81A AU543347B2 (en) | 1980-06-17 | 1981-06-11 | Benzopyrans |
IE1312/81A IE52067B1 (en) | 1980-06-17 | 1981-06-12 | Benzopyrans,their production and pharmaceutical compositions containing them |
CA000379656A CA1178598A (en) | 1980-06-17 | 1981-06-12 | Benzopyran compound, process for production thereof, and pharmaceutical composition comprising said compound |
FI811856A FI79307C (en) | 1980-06-17 | 1981-06-15 | FOR EXAMINATION OF THERAPEUTIC ANALYTICAL BAR 3,4-DIHYDRO-8- (2-HYDROXI-3-ALKYLAMINO) PROPOXI-2H-1-BENZOPYRANDERS. |
ZA814042A ZA814042B (en) | 1980-06-17 | 1981-06-16 | Benzopyran compound,process for production thereof,and pharmaceutical composition comprising said compound |
MX10178081U MX6885E (en) | 1980-06-17 | 1981-06-16 | PROCEDURE FOR PREPARING DIHYDROBENZOPYRAN COMPOUNDS |
AT81302700T ATE9582T1 (en) | 1980-06-17 | 1981-06-16 | BENZOPYRANS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. |
EP81302700A EP0042299B1 (en) | 1980-06-17 | 1981-06-16 | Benzopyrans, their production and pharmaceutical compositions containing them |
KR1019810002196A KR850000193B1 (en) | 1980-06-17 | 1981-06-16 | Process for preparing benzopyran compounds |
ES503091A ES503091A0 (en) | 1980-06-17 | 1981-06-16 | A PROCEDURE FOR OBTAINING BENZOPYRAN DERIVATIVES |
DK264181A DK154557C (en) | 1980-06-17 | 1981-06-16 | METHOD OF ANALOGUE FOR THE PREPARATION OF 3,4-DIHYDRO-8 - ((2-HYDROXY-3-ALKYLAMINO) -PROPOXY) -2H-1-BENZOPYRANDER DERIVATIVES OR A PHARMACEUTICAL ACCEPTABLE ACID ADDITIONAL SALT |
DE8181302700T DE3166300D1 (en) | 1980-06-17 | 1981-06-16 | Benzopyrans, their production and pharmaceutical compositions containing them |
NO812042A NO154495C (en) | 1980-06-17 | 1981-06-16 | ANALOGY PROCEDURE FOR PREPARING A BENZOPYRAN COMPOUND. |
SU813300799A SU1212325A3 (en) | 1980-06-17 | 1981-06-16 | Method of producing derivatives of benzopyran |
CS814509A CS226731B2 (en) | 1980-06-17 | 1981-06-16 | Method of preparing benzopyrane compounds |
DD81230894A DD160453A5 (en) | 1980-06-17 | 1981-06-17 | METHOD FOR PRODUCING BENZOPYRANE COMPOUNDS |
PL1981231734A PL130537B1 (en) | 1980-06-17 | 1981-06-17 | Method of manufacture of novel aminoalcohols,derivative of benzopyrane |
HU178481A HU188061B (en) | 1980-06-17 | 1981-06-17 | Process for the preparation of benzopyrane derivatives and pharmaceutical compositions containing said compounds as active ingredients |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP8084180A JPS6054317B2 (en) | 1980-06-17 | 1980-06-17 | New benzopyran derivatives |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS577481A true JPS577481A (en) | 1982-01-14 |
JPS6054317B2 JPS6054317B2 (en) | 1985-11-29 |
Family
ID=13729581
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP8084180A Expired JPS6054317B2 (en) | 1980-06-17 | 1980-06-17 | New benzopyran derivatives |
Country Status (2)
Country | Link |
---|---|
JP (1) | JPS6054317B2 (en) |
HU (1) | HU188061B (en) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS60181083A (en) * | 1984-02-29 | 1985-09-14 | Kowa Co | Novel racemic compound and its conversion |
JPS60208973A (en) * | 1984-03-31 | 1985-10-21 | Kowa Co | Novel optically active compound, its preparation, and drug containing it |
JPWO2004037246A1 (en) * | 2002-10-24 | 2006-02-23 | 興和株式会社 | Nerve fiber regeneration promoter |
JP2006315993A (en) * | 2005-05-12 | 2006-11-24 | Tokuyama Corp | Method for producing dihydrobenzopyran compound |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0160514U (en) * | 1987-10-14 | 1989-04-17 | ||
US7964613B2 (en) | 2007-02-28 | 2011-06-21 | Asahi Kasei Pharma Corporation | Sulfonamide compound |
JP6796351B2 (en) | 2018-04-13 | 2020-12-09 | 有限会社エコ・テクノ | Bone conduction earphone microphone |
-
1980
- 1980-06-17 JP JP8084180A patent/JPS6054317B2/en not_active Expired
-
1981
- 1981-06-17 HU HU178481A patent/HU188061B/en not_active IP Right Cessation
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS60181083A (en) * | 1984-02-29 | 1985-09-14 | Kowa Co | Novel racemic compound and its conversion |
JPS60208973A (en) * | 1984-03-31 | 1985-10-21 | Kowa Co | Novel optically active compound, its preparation, and drug containing it |
JPH0422887B2 (en) * | 1984-03-31 | 1992-04-20 | Kowa Co | |
JPWO2004037246A1 (en) * | 2002-10-24 | 2006-02-23 | 興和株式会社 | Nerve fiber regeneration promoter |
JP4675232B2 (en) * | 2002-10-24 | 2011-04-20 | 興和株式会社 | Nerve fiber regeneration promoter |
JP2006315993A (en) * | 2005-05-12 | 2006-11-24 | Tokuyama Corp | Method for producing dihydrobenzopyran compound |
Also Published As
Publication number | Publication date |
---|---|
JPS6054317B2 (en) | 1985-11-29 |
HU188061B (en) | 1986-03-28 |
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