JPS57144233A - Cyclopentene derivative - Google Patents
Cyclopentene derivativeInfo
- Publication number
- JPS57144233A JPS57144233A JP2953681A JP2953681A JPS57144233A JP S57144233 A JPS57144233 A JP S57144233A JP 2953681 A JP2953681 A JP 2953681A JP 2953681 A JP2953681 A JP 2953681A JP S57144233 A JPS57144233 A JP S57144233A
- Authority
- JP
- Japan
- Prior art keywords
- allyl
- cyclopentene
- formulai
- cis
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
NEW MATERIAL:A cyclopentene derivative of formulaI(X is H, Cl, Br, allyl; Y is H, Cl, Br, allyl; Z is H, Cl, Br, methyl, nitro, methoxy).
EXAMPLE: 3,5-cis-Bis(2-allyl-5,6-dichromophenoxy)cyclopentene.
USE: It is used as a synthetic intermediate of 5,6,7-trinor-4,8-inter-m-penylene-PGI2, which has strong hypotensive and platelet coagulation inhibiting activity.
PREPARATION: The reaction of a compound of formula II(M is sodium, potassium) with 3,5-cis-dibromocyclopentene of formula III is carried out in the presence of a phase-transtion catalyst in a solvent such as diethyl ether or tetrahydrofuran to give the compound of formulaI.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2953681A JPS57144233A (en) | 1981-03-02 | 1981-03-02 | Cyclopentene derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2953681A JPS57144233A (en) | 1981-03-02 | 1981-03-02 | Cyclopentene derivative |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS57144233A true JPS57144233A (en) | 1982-09-06 |
JPH0131494B2 JPH0131494B2 (en) | 1989-06-26 |
Family
ID=12278828
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2953681A Granted JPS57144233A (en) | 1981-03-02 | 1981-03-02 | Cyclopentene derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57144233A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1990010003A1 (en) * | 1989-02-27 | 1990-09-07 | Toray Industries, Inc. | PREPARATION OF 5,6,7-TRINOR-4,8-INTER-m-PHENYLENE PGI2 DERIVATIVES |
-
1981
- 1981-03-02 JP JP2953681A patent/JPS57144233A/en active Granted
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1990010003A1 (en) * | 1989-02-27 | 1990-09-07 | Toray Industries, Inc. | PREPARATION OF 5,6,7-TRINOR-4,8-INTER-m-PHENYLENE PGI2 DERIVATIVES |
Also Published As
Publication number | Publication date |
---|---|
JPH0131494B2 (en) | 1989-06-26 |
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