JPS5587799A - 1-beta-d-arabinofuranosyl-5-vinyluracil and its preparation - Google Patents

1-beta-d-arabinofuranosyl-5-vinyluracil and its preparation

Info

Publication number
JPS5587799A
JPS5587799A JP16008778A JP16008778A JPS5587799A JP S5587799 A JPS5587799 A JP S5587799A JP 16008778 A JP16008778 A JP 16008778A JP 16008778 A JP16008778 A JP 16008778A JP S5587799 A JPS5587799 A JP S5587799A
Authority
JP
Japan
Prior art keywords
formula
vinyluracil
arabinofuranosyl
preparation
react
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP16008778A
Other languages
Japanese (ja)
Other versions
JPS5635680B2 (en
Inventor
Yoshihisa Mizuno
Kazuyoshi Ikeda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yamasa Shoyu KK
Original Assignee
Yamasa Shoyu KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamasa Shoyu KK filed Critical Yamasa Shoyu KK
Priority to JP16008778A priority Critical patent/JPS5587799A/en
Publication of JPS5587799A publication Critical patent/JPS5587799A/en
Publication of JPS5635680B2 publication Critical patent/JPS5635680B2/ja
Granted legal-status Critical Current

Links

Abstract

NEW MATERIAL:1-β-D-Arabinofuranosyl-5-vinyluracil of formula I.
USE: Antiviral agent: it has antiviral activity, but weak activity of suppressing cellular propagation.
PREPARATION: 1-β-D-Aabinofuranosyl-5-hydroxymethyluracil of formula II is made to react with a hydrogen halide preferably in a reaction solvent as ether to form 5-halogenomethyl derivative. A phosphine derivative is made to act on the product to give a phosphonium salt of formula III (R is the residue of phosphonium salt), which is made to react with formaldehyde in the presence of a strong alkali to prepare the objective compound of formula I.
COPYRIGHT: (C)1980,JPO&Japio
JP16008778A 1978-12-27 1978-12-27 1-beta-d-arabinofuranosyl-5-vinyluracil and its preparation Granted JPS5587799A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP16008778A JPS5587799A (en) 1978-12-27 1978-12-27 1-beta-d-arabinofuranosyl-5-vinyluracil and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP16008778A JPS5587799A (en) 1978-12-27 1978-12-27 1-beta-d-arabinofuranosyl-5-vinyluracil and its preparation

Publications (2)

Publication Number Publication Date
JPS5587799A true JPS5587799A (en) 1980-07-02
JPS5635680B2 JPS5635680B2 (en) 1981-08-19

Family

ID=15707574

Family Applications (1)

Application Number Title Priority Date Filing Date
JP16008778A Granted JPS5587799A (en) 1978-12-27 1978-12-27 1-beta-d-arabinofuranosyl-5-vinyluracil and its preparation

Country Status (1)

Country Link
JP (1) JPS5587799A (en)

Also Published As

Publication number Publication date
JPS5635680B2 (en) 1981-08-19

Similar Documents

Publication Publication Date Title
JPS57176982A (en) Dioxolanylazetidinone compound, its preparation and use
JPS5587799A (en) 1-beta-d-arabinofuranosyl-5-vinyluracil and its preparation
JPS5414908A (en) Preparation of ethers
JPS5583791A (en) 7-methoxycephalosporin derivative and its preparation
JPS5430102A (en) Carbon-carbon bond formation
JPS52285A (en) Preparation of n1 *22tetrahydrofuryl**55fluorouracil
JPS54128507A (en) Preparation of ethylene glycol
JPS5410399A (en) Preparation of polyalkylene glycol derivative
JPS53141205A (en) Preparation of 3,7-dimethyl-2,6-octadienylamine derivatives
JPS5742643A (en) 6,10,14,18-tetramethyl-5,9,13,17-nonadecatetraene-2-ol
JPS5436274A (en) Preparation of propiophenone derivative
JPS5536432A (en) 11-methyl-cis-9-12-tridecadienyl acetate
JPS53124221A (en) Preparation of phosphoroamidate having hydroxyalkyl group
JPS52100425A (en) Preparation of thioether derivatives
JPS5721321A (en) Antihyperlipemic agent
JPS549250A (en) Synthesis of n-mono-substituted aminobenzophenone derivatives
JPS57144233A (en) Cyclopentene derivative
JPS5527121A (en) Novel estradiol compound, its preparation and anti-tumor agent containing the same
JPS5481253A (en) 2-methyl-2-hydroxyperhydrotriquinacene
JPS5312830A (en) Preparation of dinitrodiphenyl ether
JPS5253839A (en) Preparation of 2-(2,2-dihalovinyl) cyclopropane crboxylic acids
JPS52148037A (en) Preparation of per-#-toluylic acid
JPS53108983A (en) Preparation of 5-fluorouracil
JPS5353630A (en) Preparation of benzyl alcohol derivatives containing an ether bond at thep-position
JPS54100398A (en) Meso-tetra(p-sulfophenyl)porphine derivative