FR2100745A1 - - Google Patents

Info

Publication number
FR2100745A1
FR2100745A1 FR7121129A FR7121129A FR2100745A1 FR 2100745 A1 FR2100745 A1 FR 2100745A1 FR 7121129 A FR7121129 A FR 7121129A FR 7121129 A FR7121129 A FR 7121129A FR 2100745 A1 FR2100745 A1 FR 2100745A1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7121129A
Other languages
French (fr)
Other versions
FR2100745B1 (US07922777-20110412-C00004.png
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ono Pharmaceutical Co Ltd
Original Assignee
Ono Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ono Pharmaceutical Co Ltd filed Critical Ono Pharmaceutical Co Ltd
Publication of FR2100745A1 publication Critical patent/FR2100745A1/fr
Application granted granted Critical
Publication of FR2100745B1 publication Critical patent/FR2100745B1/fr
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0025Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0012Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
    • C08B37/0015Inclusion compounds, i.e. host-guest compounds, e.g. polyrotaxanes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nanotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FR7121129A 1970-06-10 1971-06-10 Expired FR2100745B1 (US07922777-20110412-C00004.png)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP45050119A JPS503362B1 (US07922777-20110412-C00004.png) 1970-06-10 1970-06-10

Publications (2)

Publication Number Publication Date
FR2100745A1 true FR2100745A1 (US07922777-20110412-C00004.png) 1972-03-24
FR2100745B1 FR2100745B1 (US07922777-20110412-C00004.png) 1974-08-30

Family

ID=12850213

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7121129A Expired FR2100745B1 (US07922777-20110412-C00004.png) 1970-06-10 1971-06-10

Country Status (22)

Country Link
US (1) US3816393A (US07922777-20110412-C00004.png)
JP (1) JPS503362B1 (US07922777-20110412-C00004.png)
AT (1) AT332570B (US07922777-20110412-C00004.png)
BE (1) BE768288A (US07922777-20110412-C00004.png)
CA (1) CA958007A (US07922777-20110412-C00004.png)
CH (1) CH568259A5 (US07922777-20110412-C00004.png)
CS (1) CS170169B2 (US07922777-20110412-C00004.png)
CY (1) CY895A (US07922777-20110412-C00004.png)
DE (1) DE2128674C2 (US07922777-20110412-C00004.png)
DK (1) DK140837B (US07922777-20110412-C00004.png)
ES (1) ES392074A1 (US07922777-20110412-C00004.png)
FR (1) FR2100745B1 (US07922777-20110412-C00004.png)
GB (1) GB1351238A (US07922777-20110412-C00004.png)
HK (1) HK17577A (US07922777-20110412-C00004.png)
HU (1) HU163135B (US07922777-20110412-C00004.png)
IE (1) IE35326B1 (US07922777-20110412-C00004.png)
NL (1) NL162901C (US07922777-20110412-C00004.png)
NO (1) NO134373C (US07922777-20110412-C00004.png)
RO (1) RO62182A (US07922777-20110412-C00004.png)
SE (1) SE390818B (US07922777-20110412-C00004.png)
SU (1) SU404225A3 (US07922777-20110412-C00004.png)
ZA (1) ZA713398B (US07922777-20110412-C00004.png)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2132859A1 (US07922777-20110412-C00004.png) * 1971-04-12 1972-11-24 Upjohn Co
FR2134673A1 (en) * 1971-04-30 1972-12-08 Ono Pharmaceutical Co Novel optically active isomers of prostaglandin analoguesof natural configuration useful as hypotensive agents, diuretics,contraceptives, for treating gastric ulcer and asthma, and forinhibiting platelet aggregation
FR2191900A1 (US07922777-20110412-C00004.png) * 1972-07-06 1974-02-08 Ono Pharmaceutical Co
FR2193609A1 (US07922777-20110412-C00004.png) * 1972-07-24 1974-02-22 Upjohn Co
FR2196812A1 (US07922777-20110412-C00004.png) * 1972-08-24 1974-03-22 Ono Pharmaceutical Co
FR2204421A1 (US07922777-20110412-C00004.png) * 1972-10-27 1974-05-24 Ono Pharmaceutical Co
FR2313019A2 (fr) * 1975-06-04 1976-12-31 Ono Pharmaceutical Co Nouveaux analogues de prostaglandines et leur procede de preparation
FR2398498A1 (fr) * 1977-05-06 1979-02-23 Ono Pharmaceutical Co Compositions stabilisees a usage pharmacologique contenant un analogue de la prostaglandine i2

Families Citing this family (71)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4163108A (en) * 1967-02-16 1979-07-31 Lever Brothers Company Prostaglandins
US4054736A (en) * 1970-06-10 1977-10-18 Ono Pharmaceutical Co., Ltd. Clathrate compounds of prostaglandins or their analogues with cyclodextrin
US3903131A (en) * 1971-04-12 1975-09-02 Upjohn Co 16 and 16,16-dimethyl PGE{HD 2{B
US3954833A (en) * 1971-04-12 1976-05-04 The Upjohn Company 16,16-Methyl and ethyl substituted PGF2.sub.α compounds
US4045467A (en) * 1972-02-18 1977-08-30 May & Baker Limited Cyclopentane derivatives
US4082789A (en) * 1972-03-28 1978-04-04 The University Court Of The University Of Edinburgh Prostaglandins C2
US4141914A (en) * 1972-07-24 1979-02-27 American Cyanamid Company Novel 11-deoxy-11-substituted prostaglandins of the E and F series
US4110368A (en) * 1972-07-24 1978-08-29 American Cyanamid Company Hydro substituted prostanoic acids and esters
US3962312A (en) * 1972-09-21 1976-06-08 Ono Pharmaceutical Company 9,11,15-Trihydroxy prost-5-enoic acid analogues
US3972917A (en) * 1972-10-27 1976-08-03 American Home Products Corporation 11-Deoxy 15-methyl prostaglandin E1
US4092427A (en) * 1973-04-16 1978-05-30 American Home Products Corporation Method of inducing abortion using alkyl derivatives of prostanoic acids
JPS5623984B2 (US07922777-20110412-C00004.png) * 1973-04-19 1981-06-03
US4059576A (en) * 1973-08-06 1977-11-22 Hoffmann-La Roche, Inc. 11-Substituted prostaglandins
US4246426A (en) * 1973-08-06 1981-01-20 Hoffmann-La Roche Inc. 11-Substituted prostaglandins
US4052446A (en) * 1973-08-06 1977-10-04 Hoffmann-La Roche Inc. 11,16-substituted prostaglandins
US4026927A (en) * 1973-09-25 1977-05-31 Yamanouchi Pharmaceutical Co., Ltd. Novel prostaglandin derivatives
US4036954A (en) * 1973-11-02 1977-07-19 Yamanouchi Pharmaceutical Co., Ltd. Stable prostaglandin E group-containing formulation
GB1448268A (en) * 1973-11-13 1976-09-02 May & Baker Ltd Cyclopentane derivatives
US4041066A (en) * 1974-02-07 1977-08-09 The Upjohn Company 4,5-Cis-didehydro-PGE1 compounds
GB1441564A (en) * 1974-02-07 1976-07-07 Upjohn Co Prostaglandins
DE2416193C2 (de) * 1974-04-03 1985-08-14 Hoechst Ag, 6230 Frankfurt Prostaglandin-Analoge, Verfahren zu ihrer Herstellung sowie ihre Verwendung als cytoprotektives Mittel
US4256651A (en) * 1974-10-02 1981-03-17 The Upjohn Company 2a,2b-Dihomo-15-alkyl-PGF1β compounds
US3974195A (en) * 1974-10-02 1976-08-10 The Upjohn Company 2A,2B-Dihomo-15-alkyl-PGF2.sub.α analogs
GB1482010A (en) * 1974-10-28 1977-08-03 Ono Pharmaceutical Co Prostaglandin analogues
DK142235B (da) * 1974-12-20 1980-09-29 Yamanouchi Pharma Co Ltd Analogifremgangsmåde til fremstilling af 20-alkoxy-16-methyl-prostadiensyre-derivater.
US4209637A (en) * 1975-02-24 1980-06-24 The Upjohn Company 2,2-Difluoro-PGF2 analogs
US4207420A (en) * 1975-02-24 1980-06-10 The Upjohn Company 2,2-Difluoro-PGF1 analogs
US4059701A (en) * 1975-04-17 1977-11-22 American Home Products Corporation 15-Substituted prostanoic acids for treating bronchial spasm
US4086269A (en) * 1975-07-07 1978-04-25 American Home Products Corporation 11-Deoxy-15-substituted prostaglandins
US4026909A (en) * 1975-07-14 1977-05-31 The Upjohn Company Cis-13-PGF2.sub.α analogs
US4033989A (en) * 1975-09-17 1977-07-05 The Upjohn Company 9-Deoxy-PGF2 Analogs
US4016184A (en) * 1975-09-17 1977-04-05 The Upjohn Company 9-Deoxy-9,10-didehydro-PGD1 compounds
US4013695A (en) * 1975-10-02 1977-03-22 The Upjohn Company 4,4,5,5-Tetradehydro-PGE1 analogs
US4053502A (en) * 1975-10-02 1977-10-11 The Upjohn Company 4,4,5,5-Tetradehydro-ω-aryl-PGE1 analogs
US4053500A (en) * 1975-10-02 1977-10-11 The Upjohn Company 4,4,5,5-Tetradehydro-ω-aryl-PGF1α analogs
US4026919A (en) * 1975-10-23 1977-05-31 The Upjohn Company PGD2 Substituted esters
US4058665A (en) * 1975-11-06 1977-11-15 Yamanouchi Pharmaceutical Co., Ltd. Novel 3,15-dilower alkyl PGE2 derivatives
US4212986A (en) * 1976-09-17 1980-07-15 The Upjohn Company 2,2-Difluoro-PGE2 analogs
US4212987A (en) * 1976-09-17 1980-07-15 The Upjohn Company 2,2-Difluoro-PGE1 analogs
US4169895A (en) * 1976-09-28 1979-10-02 Pfizer Inc. Antisecretory 16,16-dimethyl-17-oxaprostaglandins
HU179141B (US07922777-20110412-C00004.png) * 1977-09-23 1982-08-28
JPS5577440U (US07922777-20110412-C00004.png) * 1978-11-25 1980-05-28
US4244883A (en) * 1979-09-12 1981-01-13 The Upjohn Company 2a,2b-Dihomo-15-alkyl-PGF2β compounds
ZA831186B (en) * 1982-03-22 1983-11-30 Upjohn Ltd Gelled pge2/triacetin solutions
DE3504044A1 (de) * 1985-02-04 1986-08-07 Schering AG, Berlin und Bergkamen, 1000 Berlin 9-halogenprostaglandin-clathrate und ihre verwendung als arzneimittel
DE3608088C2 (de) * 1986-03-07 1995-11-16 Schering Ag Pharmazeutische Präparate, enthaltend Cyclodextrinclathrate von Carbacyclinderivaten
DE3740838A1 (de) * 1987-11-27 1989-06-08 Schering Ag Cyclodextrinclathrate von 5-cyano-prostacyclinderivaten und ihre verwendung als arzneimittel
US5221695A (en) * 1987-12-22 1993-06-22 Glaxo Group Limited Aqueous formulation containing a piperidinylcyclopentylheptenoic acid derivative and beta-cyclodextrin
GR880100854A (el) * 1987-12-22 1994-03-31 Glaxo Group Ltd Υδατικές διαμορφώσεις που περιέχουν ενα παράγωγο πιπεριδινυλκυκλοπεντυλεπτενοικού οξέος.
US5376645A (en) * 1990-01-23 1994-12-27 University Of Kansas Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof
KR0166088B1 (ko) * 1990-01-23 1999-01-15 . 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도
US5874418A (en) * 1997-05-05 1999-02-23 Cydex, Inc. Sulfoalkyl ether cyclodextrin based solid pharmaceutical formulations and their use
DE19828881A1 (de) * 1998-06-22 1999-12-23 Schering Ag Oxidationsinhibitor bei Prostan-Derivaten
US6287603B1 (en) 1999-09-16 2001-09-11 Nestec S.A. Cyclodextrin flavor delivery systems
ATE500218T1 (de) 2001-07-23 2011-03-15 Ono Pharmaceutical Co Mittel zur behandlung von erkrankungen, die mit knochenschwund einhergehen, mit ep4-agonist als wirkstoff
HUE029417T2 (en) 2002-10-10 2017-02-28 Ono Pharmaceutical Co Microspheres containing ONO-1301
US20070270489A1 (en) 2003-07-25 2007-11-22 Ono Pharmaceutical Co., Ltd. Remedy for Cartilage-Related Diseases
CN100542537C (zh) * 2004-07-27 2009-09-23 中国人民解放军军事医学科学院毒物药物研究所 前列腺素e1口腔制剂
EP1891083A1 (en) * 2005-06-13 2008-02-27 Cargill Incorporated Cyclodextrin inclusion complexes and methods of preparing same
WO2006137959A1 (en) * 2005-06-13 2006-12-28 Cargill, Incorporated Cyclodextrin inclusion complexes and methods of preparing same
KR20090016702A (ko) * 2006-06-13 2009-02-17 카아길, 인코포레이팃드 큰 입자 시클로덱스트린 포접 착물 및 이의 제조 방법
US20100160623A1 (en) * 2006-12-27 2010-06-24 Cargill, Incorporated Cyclodextrin inclusion complexes and methods of preparing same
CN101663034B (zh) 2007-02-16 2014-11-05 小野药品工业株式会社 用于排尿障碍的治疗剂
EP2147672A4 (en) 2007-05-08 2011-11-02 Nat University Corp Hamamatsu University School Of Medicine CYTOTOXIC T CELL ACTIVATOR WITH AN EP4 AGONIST
US20080283693A1 (en) * 2007-05-15 2008-11-20 Evans Michael J F Propulsion apparatus and system
AU2010259585B2 (en) 2009-06-10 2015-11-19 Ono Pharmaceutical Co., Ltd. Compound having detrusor muscle-contracting activity and urethral sphincter muscle-relaxing activity
JP4890657B1 (ja) * 2011-06-03 2012-03-07 小野薬品工業株式会社 リマプロストとβ−シクロデキストリンを含有する錠剤
RU2627842C2 (ru) 2011-08-02 2017-08-14 Оно Фармасьютикал Ко., Лтд. Средство для улучшения диастолической функции левого желудочка
PT2891651T (pt) 2012-08-31 2017-05-08 Ono Pharmaceutical Co Sal de amina e cristais do mesmo
CN109071427A (zh) 2016-05-09 2018-12-21 Agc株式会社 新型的前列腺素衍生物
WO2023037934A1 (ja) * 2021-09-13 2023-03-16 富士フイルム株式会社 ビシクロアルカン化合物の包摂体の製造方法

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2132859A1 (US07922777-20110412-C00004.png) * 1971-04-12 1972-11-24 Upjohn Co
FR2134673A1 (en) * 1971-04-30 1972-12-08 Ono Pharmaceutical Co Novel optically active isomers of prostaglandin analoguesof natural configuration useful as hypotensive agents, diuretics,contraceptives, for treating gastric ulcer and asthma, and forinhibiting platelet aggregation
FR2191900A1 (US07922777-20110412-C00004.png) * 1972-07-06 1974-02-08 Ono Pharmaceutical Co
FR2193609A1 (US07922777-20110412-C00004.png) * 1972-07-24 1974-02-22 Upjohn Co
FR2196812A1 (US07922777-20110412-C00004.png) * 1972-08-24 1974-03-22 Ono Pharmaceutical Co
FR2204421A1 (US07922777-20110412-C00004.png) * 1972-10-27 1974-05-24 Ono Pharmaceutical Co
FR2313019A2 (fr) * 1975-06-04 1976-12-31 Ono Pharmaceutical Co Nouveaux analogues de prostaglandines et leur procede de preparation
FR2398498A1 (fr) * 1977-05-06 1979-02-23 Ono Pharmaceutical Co Compositions stabilisees a usage pharmacologique contenant un analogue de la prostaglandine i2

Also Published As

Publication number Publication date
IE35326B1 (en) 1976-01-07
NO134373C (US07922777-20110412-C00004.png) 1976-09-29
AT332570B (de) 1976-10-11
ZA713398B (en) 1972-01-26
DK140837B (da) 1979-11-26
CA958007A (en) 1974-11-19
CH568259A5 (US07922777-20110412-C00004.png) 1975-10-31
DE2128674A1 (de) 1971-12-16
CS170169B2 (US07922777-20110412-C00004.png) 1976-08-27
IE35326L (en) 1971-12-10
DE2128674C2 (de) 1982-06-24
HK17577A (en) 1977-04-22
SU404225A3 (US07922777-20110412-C00004.png) 1973-10-26
NO134373B (US07922777-20110412-C00004.png) 1976-06-21
DK140837C (US07922777-20110412-C00004.png) 1981-09-07
RO62182A (US07922777-20110412-C00004.png) 1977-07-15
NL7107894A (US07922777-20110412-C00004.png) 1971-12-14
BE768288A (fr) 1971-11-03
HU163135B (US07922777-20110412-C00004.png) 1973-06-28
CY895A (en) 1977-10-07
FR2100745B1 (US07922777-20110412-C00004.png) 1974-08-30
ES392074A1 (es) 1974-08-01
NL162901C (nl) 1980-07-15
SE390818B (sv) 1977-01-24
JPS503362B1 (US07922777-20110412-C00004.png) 1975-02-04
NL162901B (nl) 1980-02-15
GB1351238A (en) 1974-04-24
ATA480371A (de) 1976-01-15
US3816393A (en) 1974-06-11

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Legal Events

Date Code Title Description
ST Notification of lapse