FR2081583A1 - Threonine proto-glutamate - as hepatoprotective agent - Google Patents

Threonine proto-glutamate - as hepatoprotective agent

Info

Publication number
FR2081583A1
FR2081583A1 FR7010465A FR7010465A FR2081583A1 FR 2081583 A1 FR2081583 A1 FR 2081583A1 FR 7010465 A FR7010465 A FR 7010465A FR 7010465 A FR7010465 A FR 7010465A FR 2081583 A1 FR2081583 A1 FR 2081583A1
Authority
FR
France
Prior art keywords
threonine
proto
glutamate
hepatoprotective agent
active ingredient
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7010465A
Other languages
French (fr)
Other versions
FR2081583B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to FR7010465A priority Critical patent/FR2081583A1/en
Publication of FR2081583A1 publication Critical patent/FR2081583A1/en
Application granted granted Critical
Publication of FR2081583B1 publication Critical patent/FR2081583B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/557—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. orotic acid

Abstract

Therapentic compns. containing threonine orotoglutamate as active ingredient. Hepatoprotective agents for treating man and animals at a dose of 1g daily of active ingredient. Admin. orally or parenterally. Prepared by adding excess orotic acid to a saturated aqueous solution of threonine and neutralizing excess orotic acid with glutamic acid at 40 degrees C.
FR7010465A 1970-03-24 1970-03-24 Threonine proto-glutamate - as hepatoprotective agent Granted FR2081583A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7010465A FR2081583A1 (en) 1970-03-24 1970-03-24 Threonine proto-glutamate - as hepatoprotective agent

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7010465A FR2081583A1 (en) 1970-03-24 1970-03-24 Threonine proto-glutamate - as hepatoprotective agent

Publications (2)

Publication Number Publication Date
FR2081583A1 true FR2081583A1 (en) 1971-12-10
FR2081583B1 FR2081583B1 (en) 1973-04-06

Family

ID=9052776

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7010465A Granted FR2081583A1 (en) 1970-03-24 1970-03-24 Threonine proto-glutamate - as hepatoprotective agent

Country Status (1)

Country Link
FR (1) FR2081583A1 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2449409A1 (en) * 1979-02-23 1980-09-19 Roberti Andre Acceleration of animal growth - by feeding threonine proto-glutamate plus N-methyl-glucamine
WO1980002372A1 (en) * 1979-05-07 1980-11-13 Massachusetts Inst Technology Process and composition for regulating glycine levels in the brain and spinal cord

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NEANT *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2449409A1 (en) * 1979-02-23 1980-09-19 Roberti Andre Acceleration of animal growth - by feeding threonine proto-glutamate plus N-methyl-glucamine
WO1980002372A1 (en) * 1979-05-07 1980-11-13 Massachusetts Inst Technology Process and composition for regulating glycine levels in the brain and spinal cord
EP0028257A1 (en) * 1979-05-07 1981-05-13 Massachusetts Inst Technology L-threonine for regulating glycine levels in the brain and spinal cord.
EP0028257A4 (en) * 1979-05-07 1981-09-11 Massachusetts Inst Technology L-threonine for regulating glycine levels in the brain and spinal cord.

Also Published As

Publication number Publication date
FR2081583B1 (en) 1973-04-06

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Legal Events

Date Code Title Description
ST Notification of lapse