FR2081579B1 - - Google Patents

Info

Publication number
FR2081579B1
FR2081579B1 FR707009595A FR7009595A FR2081579B1 FR 2081579 B1 FR2081579 B1 FR 2081579B1 FR 707009595 A FR707009595 A FR 707009595A FR 7009595 A FR7009595 A FR 7009595A FR 2081579 B1 FR2081579 B1 FR 2081579B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR707009595A
Other languages
French (fr)
Other versions
FR2081579A1 (xx
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Delalande SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Delalande SA filed Critical Delalande SA
Priority to FR707009595A priority Critical patent/FR2081579B1/fr
Priority to BE763609A priority patent/BE763609A/xx
Priority to ZA711334A priority patent/ZA711334B/xx
Priority to LU62723D priority patent/LU62723A1/xx
Priority to IL36345A priority patent/IL36345A/xx
Priority to CH351571A priority patent/CH518952A/fr
Priority to DE19712111776 priority patent/DE2111776A1/de
Priority to ES389129A priority patent/ES389129A1/es
Priority to SE7103377A priority patent/SE380022B/xx
Priority to CS1906A priority patent/CS168555B2/cs
Priority to NL7103618A priority patent/NL7103618A/xx
Priority to SU1631976A priority patent/SU433680A3/ru
Priority to GB23880/71A priority patent/GB1280290A/en
Publication of FR2081579A1 publication Critical patent/FR2081579A1/fr
Application granted granted Critical
Publication of FR2081579B1 publication Critical patent/FR2081579B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/092—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings with aromatic radicals attached to the chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FR707009595A 1970-03-18 1970-03-18 Expired FR2081579B1 (xx)

Priority Applications (13)

Application Number Priority Date Filing Date Title
FR707009595A FR2081579B1 (xx) 1970-03-18 1970-03-18
BE763609A BE763609A (fr) 1970-03-18 1971-03-01 Nouveaux derives de la benzhydryl piperazine leur procede de preparation et leur application en therapeutique (
ZA711334A ZA711334B (en) 1970-03-18 1971-03-02 Novel derivatives of benzhydryl piperazine,their process of preparation and their therepeutic application
LU62723D LU62723A1 (xx) 1970-03-18 1971-03-04
IL36345A IL36345A (en) 1970-03-18 1971-03-04 Benzhydryl-piperazine derivatives,their preparation and pharmaceutical compositions containing them
CH351571A CH518952A (fr) 1970-03-18 1971-03-10 Procédé de préparation de nouveaux dérivés de la benzhydryl pipérazine
DE19712111776 DE2111776A1 (de) 1970-03-18 1971-03-11 Benzhydrylpiperazinderivate
ES389129A ES389129A1 (es) 1970-03-18 1971-03-11 Procedimiento de preparacion de nuevos derivados de la ben-zhidrilpiperazina.
SE7103377A SE380022B (xx) 1970-03-18 1971-03-16
CS1906A CS168555B2 (xx) 1970-03-18 1971-03-16
NL7103618A NL7103618A (xx) 1970-03-18 1971-03-18
SU1631976A SU433680A3 (xx) 1970-03-18 1971-03-18
GB23880/71A GB1280290A (en) 1970-03-18 1971-04-19 Novel derivatives of benzhydrylpiperazine, their process of preparation and their therapeutic application

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR707009595A FR2081579B1 (xx) 1970-03-18 1970-03-18

Publications (2)

Publication Number Publication Date
FR2081579A1 FR2081579A1 (xx) 1971-12-10
FR2081579B1 true FR2081579B1 (xx) 1973-04-06

Family

ID=9052424

Family Applications (1)

Application Number Title Priority Date Filing Date
FR707009595A Expired FR2081579B1 (xx) 1970-03-18 1970-03-18

Country Status (13)

Country Link
BE (1) BE763609A (xx)
CH (1) CH518952A (xx)
CS (1) CS168555B2 (xx)
DE (1) DE2111776A1 (xx)
ES (1) ES389129A1 (xx)
FR (1) FR2081579B1 (xx)
GB (1) GB1280290A (xx)
IL (1) IL36345A (xx)
LU (1) LU62723A1 (xx)
NL (1) NL7103618A (xx)
SE (1) SE380022B (xx)
SU (1) SU433680A3 (xx)
ZA (1) ZA711334B (xx)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO155805C (no) * 1981-02-06 1987-06-10 Ucb Sa Analogifremgangsmaate for fremstilling av terapeutisk virksomme 2-(4-(difenylmethyl)-1-piperazinyl)-eddiksyrer og deres amider og ikke-toksiske salter.
DE3318577A1 (de) * 1982-05-25 1983-12-01 Fordonal S.A., Madrid Piperazinderivate
JPS59101475A (ja) * 1982-12-02 1984-06-12 Nippon Chemiphar Co Ltd 新規ピペラジン誘導体およびその製造法ならびにこれを含有する脳循環改善剤
JPS59118765A (ja) * 1982-12-24 1984-07-09 Fujisawa Pharmaceut Co Ltd ピペラジン誘導体
JP2624372B2 (ja) * 1990-11-15 1997-06-25 宇部興産株式会社 ジアリールメトキシピペリジン誘導体
US7355042B2 (en) 2001-10-16 2008-04-08 Hypnion, Inc. Treatment of CNS disorders using CNS target modulators
SI2041088T1 (sl) 2006-06-28 2014-05-30 Amgen Inc. Inhibitorji transporter-1 glicina

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1049383B (de) * 1959-01-29 Forest Brüssel Henri Morren (Belgien) Verfahren zur Herstellung von antihistaminaktiven Pipcrazinderivaten
BE649848A (xx) * 1963-07-03 1964-12-29

Also Published As

Publication number Publication date
LU62723A1 (xx) 1971-10-13
CS168555B2 (xx) 1976-06-29
ES389129A1 (es) 1973-06-01
IL36345A0 (en) 1971-05-26
SE380022B (xx) 1975-10-27
CH518952A (fr) 1972-02-15
DE2111776A1 (de) 1971-10-07
NL7103618A (xx) 1971-09-21
IL36345A (en) 1974-01-14
FR2081579A1 (xx) 1971-12-10
ZA711334B (en) 1971-11-24
GB1280290A (en) 1972-07-05
SU433680A3 (xx) 1974-06-25
BE763609A (fr) 1971-09-01

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Legal Events

Date Code Title Description
ST Notification of lapse